Selected publications (most recent first)
Norbury, C. J. 2013. Cytoplasmic RNA: a case of the tail wagging the dog. Nature Reviews Molecular Cell Biology 14, 643-653.
Yates, L., C. J. Norbury and R. J. C. Gilbert. 2013. The long and short of microRNA. Cell 153, 516-519.
Scott, D. D., and C. J. Norbury. 2013. RNA decay via 3' uridylation. Biochimica et Biophysica Acta 1829, 654-665.
Yates, L., S. Fleurdépine, O. S. Rissland, L. de Colibus, K. Harlos, C. J. Norbury and R. J. C. Gilbert. 2012. Structural basis for the activity of a cytoplasmic RNA terminal U-transferase. Nature Structural & Molecular Biology 19, 782-787.
Norbury, C. J. 2011. Regional specialization: the NEXT big thing in nuclear RNA turnover. Mol Cell 43: 502-504.
Schmidt, M-J., West, S. and C. J. Norbury. 2011. The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation. RNA 17: 39-44.
Grzmil, M., T. Rzymski, M. Milani, A. L. Harris, R. G. Capper, N. J. Saunders, A. Salhan, J. Ragoussis, and C. J. Norbury. 2010. An oncogenic role of eIF3e/INT6 in human breast cancer. Oncogene 29:4080-4089.
Norbury, C. J. 2010. 3' Uridylation and the regulation of RNA function in the cytoplasm. Biochem Soc Trans 38:1150-1153.
Schmidt, M-J., and C. J. Norbury. 2010. Polyadenylation and beyond: emerging roles for non-canonical poly(A) polymerases. WIREs RNA doi:10.1002/wrna.16.
Pellagatti, A., M. Cazzola, A. Giagounidis, J. Perry, L. Malcovati, M. G. Della Porta, M. Jadersten, S. Killick, A. Verma, C. J. Norbury, E. Hellstrom-Lindberg, J. S. Wainscoat and J. Boultwood. 2010. Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells. Leukemia 24: 756-764 .
Rissland, O. S., and C. J. Norbury. 2009. Decapping is preceded by 3' uridylation in a novel pathway of bulk mRNA turnover. Nature Structural & Molecular Biology 16: 616-623.
Liew, L. P., and C. J. Norbury. 2009. Telomere maintenance: all's well that ends well. Arch Toxicol 83: 407-416.
Rissland, O. S., and C. J. Norbury. 2008. The Cid1 poly(U) polymerase. BBA Gene Regulatory Mechanisms 1779: 286-294.
Grzmil, M., D. Whiting, J. Maule, C. Anastasaki, J. F. Amatruda, R.N. Kelsh, C. J. Norbury and E. E. Patton. 2007. The INT6 cancer gene and MEK signaling pathways converge during zebrafish development. PLoS One 2:e959.
Rissland, O. S., A. Mikulasova and C. J. Norbury. 2007. Efficient RNA polyuridylation by non-canonical poly(A) polymerases. Mol Cell Biol 27: 3612-3624.
Talbot D. C., J. von Pawel, E. Cattell, S. M. Yule, C. Johnston, A. S. Zandvliet, A. D. Huitema, C. J. Norbury, P. Ellis, L. Bosquee and M. Reck. 2007. A randomized phase II pharmacokinetic and pharmacodynamic study of indisulam as second-line therapy in patients with advanced non-small cell lung cancer. Clin Cancer Res 13:1816-22.
West, S., N. Gromak, C. J. Norbury and N. J. Proudfoot. 2006. Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cells. Mol Cell 21: 437-43.
Win, T. Z., S. Draper, R. L. Read, J. Pearce, C. J. Norbury and S. W. Wang. 2006. Requirement of fission yeast Cid14 in polyadenylation of rRNAs. Mol Cell Biol 26: 1710-1721.
Jenkins, C. C. L., J. Mata, R. F. Crane, B. Thomas, A. Akoulitchev, J. Bähler and C. J. Norbury. 2005. Activation of AP-1-dependent transcription by a truncated translation initiation factor. Euk. Cell 4: 1840-1850.
Norbury, C. J. 2005. The cancer cell cycle. pp 156-169 In M. Knowles and P. Selby (eds), Cellular & Molecular Biology of Cancer. Oxford University Press.
Wang, S. W., K. Asakawa, T. Z. Win, T. Toda and C. J. Norbury. 2005. Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defects. Mol. Cell. Biol. 25: 2288-2296.
Win, T. Z., A. Goodwin, I. D. Hickson, C. J. Norbury and S. W. Wang. 2004. Requirement for Schizosaccharomyces pombe Top3 in the maintenance of chromosome integrity. J. Cell Sci. 117: 4769-4778.
Watkins, S. J. and C. J. Norbury. 2004. Cell cycle-related variation in sub-cellular localization of eIF3e/INT6 in human fibroblasts. Cell Prolif. 37:149-160.
Norbury, C. J. and B. Zhivotovsky. 2004. DNA damage-induced apoptosis. Oncogene 23:2797-808.
Kranc, K. R., S. D. Bamforth, J. Braganca, C. J. Norbury M. van Lohuizen and S. Bhattacharya. 2003. Transcriptional co-activator Cited2 induces Bmi1 and Mel18 to repress Cdkn2a and enhance cell proliferation. Mol. Cell. Biol. 23:7658-7666.
Winters, Z. E., R. D. Leek, M. J. Bradburn, C. J. Norbury and A. L. Harris. 2003. Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/neu in breast cancer and is an independent predictor of prognosis. Breast Cancer Res. 5:R242-R249.
Read, R. L., R. Martinho, S. W. Wang, A. M. Carr, and C. J. Norbury. 2002. Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest. Proc. Natl Acad. Sci. USA 99:12079-12084.
Watkins, S. J., and C. J. Norbury. 2002. Translation initiation and its deregulation during tumorigenesis. Br. J. Cancer 86:1023-7.
Wang, S. W., R. L. Read, and C. J. Norbury. 2002. Fission yeast Pds5 is required for accurate chromosome segregation and for survival after DNA damage or metaphase arrest. J. Cell Sci. 115:587-98.
Read, R. L., and C. J. Norbury. 2002. Roles for cytoplasmic polyadenylation in cell cycle regulation. J. Cell. Biochem. 87:258-265.
Dunand-Sauthier, I., C. Walker, C. Wilkinson, C. Gordon, R. Crane, C. J. Norbury, and T. Humphrey. 2002. Sum1, a component of the fission yeast eIF3 translation initiation complex, is rapidly relocalized during environmental stress, and interacts with components of the 26S proteasome. Mol. Biol. Cell 13:1626-1640.
Dixon, H., and C. J. Norbury. 2002. Therapeutic exploitation of checkpoint defects in cancer cells lacking p53 function. Cell Cycle 1:362-368.
Norbury, C. J., and I. D. Hickson. 2001. Cellular responses to DNA damage. Annu. Rev. Pharmacol. Toxicol. 41:367-401.
Wang, S. W., A. Goodwin, I. D. Hickson, and C. J. Norbury. 2001. Involvement of Schizosaccharomyces pombe Srs2 in cellular responses to DNA damage. Nucleic Acids Res. 29:2963-2972.
Winters, Z. E., N. C. Hunt, M. J. Bradburn, J. A. Royds, H. Turley, A. L. Harris, and C. J. Norbury. 2001. Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer: association with prognosis. Eur. J. Cancer 37:2405-2412.
Wang, S. W., T. Toda, R. MacCallum, A. L. Harris, and C. J. Norbury. 2000. Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated. Mol. Cell. Biol. 20:3234-3244.
Crane, R., R. Craig, R. Murray, I. Dunand-Sauthier, T. Humphrey, and C. J. Norbury. 2000. A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed. Mol. Biol. Cell 11:3993-4003.
Wang, S. W., C. J. Norbury, A. L. Harris, and T. Toda. 1999. Caffeine can override the S-M checkpoint in fission yeast. J. Cell Sci. 112:927-937.
Winters, Z. E., W. M. Ongkeko, A. L. Harris, and C. J. Norbury. 1998. p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells. Oncogene 17:673-684.
Spataro, V., T. Toda, R. Craig, M. Seeger, W. Dubiel, A. L. Harris, and C. J. Norbury. 1997. Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit. J. Biol. Chem. 272:30470-30475.
Ongkeko, W., D. J. Ferguson, A. L. Harris, and C. J. Norbury. 1995. Inactivation of Cdc2 increases the level of apoptosis induced by DNA damage. J. Cell Sci. 108:2897-904.
Enoch, T., and C. J. Norbury. 1995. Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM. Trends Biochem. Sci. 20:426-430.
O'Connell, M. J., C. J. Norbury, and P. Nurse. 1994. Premature chromatin condensation upon accumulation of NIMA. EMBO J. 13:4926-4937.
Norbury, C. J., and P. Nurse. 1992. Animal cell cycles and their control. Annu. Rev. Biochem. 61:441-470.
Norbury, C. J., J. Blow, and P. Nurse. 1991. Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. EMBO J. 10:3321-3329.
Th'ng, J. P., P. S. Wright, J. Hamaguchi, M. G. Lee, C. J. Norbury, P. Nurse, and E. M. Bradbury. 1990. The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product. Cell 63:313-324.
Lee, M. G., C. J. Norbury, N. K. Spurr, and P. Nurse. 1988. Regulated expression and phosphorylation of a possible mammalian cell- cycle control protein. Nature 333:676-679.
Gautier, J., C. J. Norbury, M. Lohka, P. Nurse, and J. Maller. 1988. Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+. Cell 54:433-439.