The UK Cystic Fibrosis Gene Therapy Consortium

The UKCFGTC is nade up of three groups, based in Edinburgh, London and ourselves in Oxford.
The UKCFGTC is nade up of three groups, based in Edinburgh, London and ourselves in Oxford.

In 2001, we were invited by the UK CF Trust to form a consortium with two competing research groups at Imperial College, London and the University of Edinburgh.

The aim was that by bringing the three groups together we could share funding and develop a clinically relevant treatment for CF much faster than either group could on its own

Nine years on with a combined staff of over 50, the Consortium is the largest gene therapy group focussed on a single disease anywhere in the world.

We are currently progressing with our first clinical trial programme and are aiming to complete a multi-dose study by the end of 2012.

The UK CFGTC Website


University of Edinburgh

Centre for Molecular Medicine

The Roslin Institute


Imperial College London

National Heart & Lung Institute


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How the Consortium works/FAQs

Consortium Website

Centre for Molecular Medicine, Edinburgh
The Roslin Institute
Dep of Gene Therapy, Imperial



The Run-in Study

Single Dose Clinical Trial

Multi Dose Clinical Trial


Our Research

Non-viral Vector Development

Aerosol Mediated Gene Delivery

Viral Vector Development

Taqman Core Facility

Cystic Fibrosis

History of CF

Discovery of the CFTR Gene

CFTR Protein Structure

CFTR Function

CF Links


Gene Therapy

Introduction to Gene Therapy

Other CF Gene Therapy Groups

Why use Gene Therapy for CF

Target Cells for CF Gene Therapy

Barriers for CF Gene Therapy

Clinical Trials

Gene Therapy Successes

Gene Therapy Links




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