In 2008 we were asked by Pearson Education to contribute towards a schools education programme.
They interviewed Dr Deborah Gill about the work we do and gene therapy in general. For CF week 2011 we have decided to make some this material available on our website.
An Introduction to the GeneMedicine Group^Top
In this video Dr Gill introduces the group and talks about why she became involved in this area of research.
Deborah explains how the work we do tries to use the knowledge that we have gained from human genetics to develop new treatments for Cystic Fibrosis and potentially other diseases too.
Current Strategies for Cystic Fibrosis Care^Top
In this video, Dr Gill explains how improvements in conventional treatments for CF have greatly improved the level of care available for people with the disease.
Developments in antibiotics, better diagnostics and nutrition mean that the current average life expectancy is 30-40 years.
However, for people born with CF today, the prospects are improving all the time as new therapies are developed.
What is Gene Therapy?^Top
CF gene therapy aims to insert a fully functional CFTR gene into the lung airway cells of people with the condition.
Two main types of vector are used to deliver this new copy of the gene. A viral vector, engineered from viral particles or non-viral vectors, plasmid DNA molecules condensed by other chemical entities (eg a lipid).
Prof Eric Alton talks about the progress we have made^Top
Prof Eric Alton (Imperial) gave this interview to the CF Trust following a public meeting on our work in late 2009.
BBC Horizon: Miracule Cure? October 2010^Top
In October 2010 the BBC aired a Horizon special to mark the 10th anniversary of the completion of the Human Genome Project.
CF and the work of the Consortium featured heavily in this programme. In this clip you (from 1 min 25 in) there is an interview with one of the patients on our current clinical trial and Eric Alton.