Introductory Videos to our Group and the UK CF Gene Therapy Consortium

In 2008 we were asked by Pearson Education to contribute towards a schools education programme.

They interviewed Dr Deborah Gill about the work we do and gene therapy in general. For CF week 2011 we have decided to make some this material available on our website.

Please email us or use the feedback form to let us know what you think of these videos as we have a lot of other video content that we could potentially put online.

An Introduction to the GeneMedicine Group
Current Strategies for Cystic Fibrosis Care
What is Gene Therapy?
Prof Eric Alton talks about the progress we have made
BBC Horizon, 2010


Introduction to the GeneMedicine Group.

An Introduction to the GeneMedicine Group^Top

In this video Dr Gill introduces the group and talks about why she became involved in this area of research.

Deborah explains how the work we do tries to use the knowledge that we have gained from human genetics to develop new treatments for Cystic Fibrosis and potentially other diseases too.


What is the current state of CF care?

Current Strategies for Cystic Fibrosis Care^Top

In this video, Dr Gill explains how improvements in conventional treatments for CF have greatly improved the level of care available for people with the disease.

Developments in antibiotics, better diagnostics and nutrition mean that the current average life expectancy is 30-40 years.

However, for people born with CF today, the prospects are improving all the time as new therapies are developed.


Gene therapy for CF Lung disease

What is Gene Therapy?^Top

CF gene therapy aims to insert a fully functional CFTR gene into the lung airway cells of people with the condition.

Two main types of vector are used to deliver this new copy of the gene. A viral vector, engineered from viral particles or non-viral vectors, plasmid DNA molecules condensed by other chemical entities (eg a lipid).

Professor Eric Alton (Imperial) explain how the consortium works and the progress that has been made.

Prof Eric Alton talks about the progress we have made^Top

Prof Eric Alton (Imperial) gave this interview to the CF Trust following a public meeting on our work in late 2009.


BBC Horizon, 2010.

BBC Horizon: Miracule Cure? October 2010^Top

In October 2010 the BBC aired a Horizon special to mark the 10th anniversary of the completion of the Human Genome Project.

CF and the work of the Consortium featured heavily in this programme. In this clip you (from 1 min 25 in) there is an interview with one of the patients on our current clinical trial and Eric Alton.

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