Matthew Lloyd

Matthew Lloyd matthew.lloyd@dpag.ox.ac.uk ORCID iCASE Student at the Doctoral Training Centre Rex Richards Building, South Parks Road, Oxford OX1 3QU Ashcroft Group Department of Physiology, Anatomy and Genetics, Sherrington Building, Parks Road, Oxford OX1 3PT

Background and Interests

My current research interest is in the regulation of insulin secretion and its failure in diabetes, with a focus on the effects of glycogen accumulation on beta-cell function. Why beta-cells eventually fail in type II diabetes remains unresolved, and a detailed mechanistic understanding of this process has the potential to transform therapy and reduce the huge global health burden of this disease.

Beyond my research, I am actively involved in scientific outreach and public engagement. In my free time, I enjoy a range of outdoor pursuits including wildlife and landscape photography, hiking and kayaking, as well as drawing/painting and baking.

Education

Interdisciplinary Bioscience BBSRC DTP (iCASE)
Hertford College, University of Oxford
2018-present

MBiochem Molecular and Cellular Biochemistry (first class)
Hertford College, University of Oxford
2014-2018

Research

DPhil project in the Ashcroft Group (DPAG) in partnership with Novo Nordisk
Impact of Glycogen Accumulation on Pancreatic Beta-cell Metabolism and the Regulation of Insulin Secretion

Part II project in the Vasudevan group (Department of Pharmacology, Oxford)
Modulation of Circadian Rhythms in Glucose Metabolism in Mammalian Cell Culture

Summer project in the Handford group (Department of Biochemistry, Oxford)
Characterising Interactions of the Notch Receptor Lin-12 and its Ligand Apx-1

Conferences and Courses