Matthew Lloyd

Personal photo - Matthew Lloyd

Matthew Lloyd

iCASE Student at the Doctoral Training Centre
Rex Richards Building, South Parks Road, Oxford OX1 3QU

Ashcroft Group
Department of Physiology, Anatomy and Genetics, Sherrington Building, Parks Road, Oxford OX1 3PT

Background and Interests

My current research interest is in the regulation of insulin secretion and its failure in diabetes, with a focus on the effects of glycogen accumulation on beta-cell function. Why beta-cells eventually fail in type II diabetes remains unresolved, and a detailed mechanistic understanding of this process has the potential to transform therapy and reduce the huge global health burden of this disease.

Beyond my research, I am actively involved in scientific outreach and public engagement. In my free time, I enjoy a range of outdoor pursuits including wildlife and landscape photography, hiking and kayaking, as well as drawing/painting and baking.


Interdisciplinary Bioscience BBSRC DTP (iCASE)
Hertford College, University of Oxford

MBiochem Molecular and Cellular Biochemistry (first class)
Hertford College, University of Oxford


DPhil project in the Ashcroft Group (DPAG) in partnership with Novo Nordisk
Impact of Glycogen Accumulation on Pancreatic Beta-cell Metabolism and the Regulation of Insulin Secretion

Part II project in the Vasudevan group (Department of Pharmacology, Oxford)
Modulation of Circadian Rhythms in Glucose Metabolism in Mammalian Cell Culture

Summer project in the Handford group (Department of Biochemistry, Oxford)
Characterising Interactions of the Notch Receptor Lin-12 and its Ligand Apx-1

Conferences and Courses

I have attended the EASD Scientists Training Course (Montpellier, France, November 2018), the 3rd Joint Meeting of the EASD Islet Study Group & Beta-cell Workshop (Oxford, April 2019) and the 55th EASD Annual Meeting (Barcelona, September 2019)