Selected Front Covers

172 Synthesis and Reactivity of 18F-Labeled α,α-Difluoro-α-Aryloxyacetic Acids
T. Khotavivattana, S. Calderwood, S. Verhoog, L. Pfeifer, S. Preshlock, N. Vasdev, T. Collier, V. Gouverneur
Org. Lett. 2017, (Accepted)

171 Bridging the gaps in 18F PET tracer development
M. G. Campbell, J. Mercier, C. Genicot, V. Gouverneur, J. M. Hooker, T. Ritter
Nat. Chem. 2017, 9, 1-3

170 Twisting the Ethano-Tröger’s Base: The Bisamide
J. Cvengros, R. Pereira, L. Pfeifer, J. Fournier, V. Gouverneur
Org. Biomol. Chem. 2017, DOI: 10.1039/C6OB02359B (In Print)

169 Radiosynthesis of SPECT tracers via a copper mediated 123I iodination of (hetero)aryl boron reagents
T. C. Wilson, G. McSweeney, S. Preshlock, S. Verhoog, M. Tredwell, T. Cailly, V. Gouverneur
Chem. Commun. 2016, 52, 13277-13280

168 The Dual Role of Thiourea in the Thiotrifluoromethylation of Alkenes
P. Ricci, T. Khotavivattana, L. Pfeifer, M. Médebielle, J. R. Morphy, V. Gouverneur
Chem. Sci. 2016, DOI: 10.1039/C6SC02790C (In Print)

167 On the Reactivity of α-Trifluoromethylstyrene in Radical Copolymerizations with Various Fluoroalkenes
J. Walkowiak-Kulikowska, F. Boschet, G. Kostov, V. Gouverneur, B. Ameduri
Eur. Polym. J. 2016, 84, 612-621

166 Targeting telomerase with radiolabeled inhibitors
P. A. Waghorna, M. R. Jackson, V. Gouverneur, K. A. Vallis
Eur. J. Med. Chem. 2017, 125, 117-129

165 Hydrogen-Bonded Homoleptic Fluoride–Diarylurea Complexes: Structure, Reactivity and Coordinating Power
L. Pfeifer, K. M. Engle, G. W. Pidgeon, H. A. Sparkes, A. L. Thompson, J. M. Brown, V. E. Gouverneur
J. Am. Chem. Soc., 2016, 138 (40), 13314-13325

164 Ultrafast Click Chemistry with Fluorosydnones
H. Liu, D. Audisio, L. Plougastel, E. Decuypere, D. A. Buisson, O. Koniev, S. Kolodych, A. Wagner, M. Elhabiri, A. Krzyczmonik, S. Forsback, O. Solin, V. Gouverneur, F. Taran
Angew. Chem. Int. Ed. 2016, 55 (39), 12073-12077

163 Enhanced Copper-Mediated 18F-Fluorination of Aryl Boronic Esters provides Eight Radiotracers for PET Applications
S. Preshlock, S. Calderwood, S. Verhoog, M. Tredwell, M. Huiban, A. Hienzsch, S. Gruber, T. C. Wilson, N. J. Taylor, T. Cailly, M. Schedler, T. L. Collier, J. Passchier, R. Smits, J. Mollitor, A. Hoepping, M. Mueller, C. Genicot, J. Mercier, V. Gouverneur
Chem. Commun. 2016, 52, 8361-8364

162 Asymmetric 18F-Fluorination for Applications in Positron Emission Tomography
F. Buckingham, V. Gouverneur
Chem. Sci. 2016, 7, 1645-1652

161 18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography
S. Preshlock, M. Tredwell, V. Gouverneur
Chem. Rev. 2016, 116 (2), 719–766

160 Cu-Catalyzed Heteroatom-H Bond Insertions with Trifluorodiazoalkanes
S. Hyde, J. Veliks, B. Liégault, D. Grassi, M. Taillefer, V. Gouverneur
Angew. Chem. Int. Ed. 2016, 55 (11), 3785-3789

159 Synthesis and Characterization of a Novel N-F Reagent derived from the Ethano-Tröger’s Base: 1JFN Coupling Constant as Signature for the N-F Bond
R. Pereira, J. Wolstenhulme, G. Sandford, T. D. W. Claridge, V. Gouverneur, J. Cvengroš
Chem. Commun. 2016, 52, 1606-1609

158 Ag-Mediated 18F-Labeling of Aryl-CF3 and Aryl-CHF2 with 18F-Fluoride
S. Verhoog, L. Pfeifer, T. Khotavivattana, S. Calderwood, T. L. Collier, K. Wheelhouse, M. Tredwell, V. Gouverneur
Synlett 2016, 27, 25-28. In celebration of Prof. Steven Ley's 70th birthday.

157 Synthesis of 18F-Arenes from Spirocyclic Iodonium(III) Ylides via Continuous-Flow Microfluidics
S. Calderwood, T. L. Collier, V. Gouverneur, S. H. Liang, N. Vasdev
J. Fluorine Chem. 2015, 178, 249-253

156 Organomediated Enantioselective 18F-Fluorination for PET Applications
F. Buckingham, A. K. Kirjavainen, S. Forsback, A. Krzyczmonik, T. Keller, I. M. Newington, M. Glaser, S. K. Luthra, O. Solin, V. Gouverneur
Angew. Chem. Int. Ed. 2015, 54 (45), 13366-13369

155 Oxidative Fluorination of N-Arylsulfonamides
F. Buckingham, S. Calderwood, B. Checa, T. Keller, M. Tredwell, T. L. Collier, I. M. Newington, R. Bhalla, M. Glaser, V. Gouverneur
J. Fluorine Chem. 2015, 180, 33-39

154 Cross-Coupling of [2-Aryl-1,1,2,2-tetrafluoroethyl]trimethylsilanes with Aryl Halides
M. O'Duill, E. Dubost, L. Pfeifer, V. Gouverneur
Organic Letters 2015, 17 (14), 3466-3469

153 Coordination Diversity in Hydrogen-Bonded Homoleptic Fluoride–Alcohol Complexes Modulates Reactivity
K. M. Engle, L. Pfeifer, G. W. Pidgeon, G. T. Giuffredi, A. L. Thompson, R. S. Paton, J. M. Brown, V. Gouverneur
Chem. Sci. 2015, 6, 5293-5302 (Edge Article)

152 [18F]Labeling of Aryl-SCF3, -OCF3 and -OCHF2 with [18F]Fluoride
T. Khotavivattana, S. Verhoog, M. Tredwell, L. Pfeifer, S. Calderwood, K. Wheelhouse, T. L. Collier, V. Gouverneur
Angew. Chem. Int. Ed. 2015, 54 (34), 9991-9995

151 Recruitment and Immobilization of a Fluorinated Biomarker Across an Interfacial Phospholipid Film using a Fluorocarbon Gas
G. Yang, M. O'Duill, V. Gouverneur, M. P. Krafft
Angew. Chem. Int. Ed. 2015, 54 (29), 8402-8406

150 A dual radiolabelling approach for tracking metal complexes: investigating the speciation of copper bis(thiosemicarbazonates) in vitro and in vivo
R. Hueting, V. Kersemans, M. Tredwell, B. Cornelissen, M. Christlieb, A. D. Gee, J. Passchier, S. C. Smart, V. Gouverneur, R. J. Muschel, J. R. Dilworth
Metallomics 2015, 7, 795-804

149 Iodine Transfer Copolymerization of Fluorinated α-Methylstyrenes with Styrene using 1-iodoperfluorohexane as the Chain Transfer Agent
J. Walkowiak, A. Szwajca, F. Boschet, V. Gouverneur, B. Ameduri
Macromolecules 2014, 47(24), 8634–8644

148 A Diversity Oriented Approach to CF3CHF-, CF3CFBr-, CF3CF2-, (CF3)2CH- and CF3(SCF3)CH-Substituted Arenes from 1-(Diazo-2,2,2-trifluoroethyl)arenes
E. Emer, J. Twilton, M. Tredwell, S. Calderwood, T. Collier, B. Liégault, M. Taillefer, V. Gouverneur
Org. Lett. 2014, 16(22), 6004-6007

147 Asymmetric Fluorocyclizations of Alkenes
J. Wolstenhulme, V. Gouverneur
Account of Chemical Research 2014, 47(12), 3560-3570

146 Anti-CD20 inhibits T cell-mediated pathology and microgliosis in the rat brain
D. C. Anthony, A. M. Dickens, N. Seneca, Y. Couch, S. Campbell, B. Checa, V. Kersemans, E. A. Warren, M. Tredwell, N. R. Sibson, V. Gouverneur, D. Leppert
Annals of Clinical and Translational Neurology 2014, 1 (9), 659–669

145 A General Copper-Mediated Nucleophilic 18F Fluorination of Arenes
M. Tredwell, S. M. Preshlock, N. J. Taylor, S. Gruber, M. Huiban, J. Passchier, J. Mercier, C. Génicot, V. Gouverneur
Angew. Chem. Int. Ed. 2014, 53 (30), 7751-7755

144 cis-Specific Hydrofluorination of Alkenylarenes under Palladium Catalysis by an Ionic Pathway
E. Emer, L. Pfeifer, J. M. Brown, V. Gouverneur
Angew. Chem. Int. Ed. 2014, 53 (16), 4181–4185

143 Glial Activation in the Early Stages of Brain Metastasis: TSPO as a Diagnostic Biomarker
E. R. O’Brien, V. Kersemans, M. Tredwell, B. Checa , S. Serres, M. S. Soto, V. Gouverneur, D. Leppert, D. C. Anthony, N. R. Sibson
J. Nucl. Med. 2014, 55 (2), 1-6

142 A Comparison of the Behaviour of 64Cu-acetate and 64Cu-ATSM in vitro and in vivo
R. Hueting, V. Kersemans, B. Cornelissen, M. Tredwell, K. Hussien, M. Christlieb, A. D. Gee, J. Passchier, S. C Smart, J. R Dilworth, V. Gouverneur, R. J. Muschel
J. Nucl. Med. 2014, 55 (1), 128-134

141 A Broadly Applicable [18F]Trifluoromethylation of Aryl and Heteroaryl Iodides for PET Imaging
M. Huiban, M. Tredwell, S. Mizuta, Z. Wan, X. Zhang, T. L. Collier, V. Gouverneur, J. Passchier
Nature Chemistry 2013, 5, 941-944

140 Enhanced Aqueous Suzuki-Miyaura Coupling Allows Site specific Polypeptide [18F]labeling
M. Gao, V. Gouverneur, B. Davis
J. Am. Chem. Soc., 2013, 135 (37), 13612–13615

139 Intramolecular OH...FC Hydrogen Bonding in Fluorinated Carbohydrates: CHF is a Better Hydrogen Bond Acceptor than CF2
G. T. Giuffredi, V. Gouverneur, B. Bernet
Angew. Chem. Int. Ed. 2013, 52 (40), 10524-10528

138 Asymmetric Electrophilic Fluorocarbocyclization with Carbon Nucleophiles
J. R. Woltenshulme, J. Rosenqvist, O. Lozano, J. Ilupeju, K. M. Engle, G. Pidgeon, P. R. Moore, G. Sandford, V. Gouverneur
Angew. Chem. Int. Ed. 2013, 52 (37), 9796–9800

137 Redox chemistry of trifluoromethyl sulfonium salts as CF3 radical sources
S. Mizuta, S. Verhoog, X. Wang, N. Shibata, V. Gouverneur, M. Médebielle
J. Fluorine Chem. 2013, 155, 124-131 (Special Issue in honor of Professor Ojima ACS Fluorine Award)

136 Catalytic Decarboxylative Fluorination for the Synthesis of Tri- and Difluoromethyl Arenes
S. Mizuta, I. Stenhagen, M. O'Duill, J. Wolstenhulme, A. Kirjavainen, S. Forsback, M. Tredwell, G. Sandford, P. Moore, M. Huiban, S. Luthra, J. Passchier, O. Solin, V. Gouverneur
Org. Lett. 2013, 15 (11), 2648-2651

135 Trifluoromethylation of Allylsilanes under Photoredox Catalysis
S. Mizuta, K. M. Engle, S. Verhoog, O. Galicia-Lopez, M. O’Duill, M. Medebielle, K. Wheelhouse, G. Rassias, A. Thompson, V. Gouverneur
Org. Lett. 2013, 15 (6), 1250-1253

134 Catalytic Hydrotrifluoromethylation of Unactivated Alkenes
S. Mizuta, S. Verhoog, K. M. Engle, T. Khotavivattana M. O’Duill, K. Wheelhouse, G. Rassias, M. Medebielle, V. Gouverneur
J. Am. Chem. Soc. 2013, 135 (7), 2505-2508

133 [18F]Fluorination of Arylboronic Ester using [18F]Selectfluor bis(triflate): Application to 6-[18F]Fluoro-L-DOPA
I. S. R. Stenhagen, A. K. Kirjavainen, S. J. Forsback, C. G. Jørgensen, E. G. Robins, S. K. Luthra, O. Solin, V. Gouverneur
Chem. Commun. 2013, 49, 1386-1388

132 Regio- and Stereoretentive Synthesis of Branched, Linear (E)- and (Z)-Allyl Fluorides from Allyl Carbonates under Ir-Catalysis
E. Benedetto, M. Tredwell, C. Hollingworth, T. Khotavivattana, J. M. Brown and V. Gouverneur
Chem. Sci., 2013, 4, 89-96 [Back Cover]

131 [18F]Labeling of Arenes
M. Tredwell, V. Gouverneur
Angew. Chem. Int. Ed., 2012, 51 (46), 11426-11437

130 Synthesis of 3-Fluoropyrrolidines and 4-Fluoropyrrolidin-2-ones from Allylic Fluorides
L. E. Combettes, M. Schuler, R. Patel, B. Bonillo, B. Odell, A. L. Thompson, T. D. W. Claridge, V. Gouverneur
Chemistry A European Journal, 2012, 18 (41), 13126-13132

129 Conformational Analysis of Fluorinated Pyrrolidines using 19F-1H Scalar Couplings and Heteronuclear nOes
L. E. Combettes, P. Clausen-Thue, M. King, B. Odell, A. L. Thompson, V. Gouverneur, T. D. W. Claridge
Chemistry A European Journal, 2012, 18(41), 13133-13141

128 Trifluoromethylation of Allylsilanes under Copper Catalysis
Satoshi Mizuta, Oscar Galicia-López, Keary M. Engle, Stefan Verhoog, Katherine Wheelhouse, Gerasimos Rassias, Véronique Gouverneur
Chemistry A European Journal, 2012, 18 (28), 8583-8587

127 Metal-Free Oxidative Fluorination of Phenols with [18F]Fluoride
Zhanghua Gao, Yee Hwee Lim, Matthew Tredwell, Lei Li, Stefan Verhoog, Matthew Hopkinson, Wojciech Kaluza, Thomas Lee Collier, Jan Passchier, Mickael Huiban, and Veronique Gouverneur
Angew. Chem. Int. Ed. 2012, 51 (27), 6733-6737

126 Metal Free Fluoroamination of Allylsilanes: a Route to 3-Fluoropyrrolidines
Lorraine E. Combettes, Oscar Lozano and Véronique Gouverneur
J. Fluorine Chem., 2012, 143, 167-176 (Special issue of the Journal of Fluorine Chemistry to honor Professor David O'Hagan)

125 Palladium-Catalyzed Substitution and Cross-Coupling of Benzylic Fluorides
George Blessley, Patrick Holden, Matthew Walker, John M. Brown and Véronique Gouverneur
Org. Lett., 2012, 14 (11), 2754-2757

124 Radiochemistry: Flipping fluoride's reactivity
Véronique Gouverneur
Nature Chemistry, 2012, 4, 152-154

123 A fluorous and click approach for screening potential PET probes: evaluation of potential hypoxia biomarkers
Romain Bejot, Laurence Carroll, Kishore Bhakoo and Véronique Gouverneur
Bioorganic & Medicinal Chemistry 2012, 20, 324-329

122 Platinum-Catalyzed Substitution of Allylic Fluorides
Elena Benedetto, Massaba Keita, Matthew Tredwell, Charlotte Hollingworth, John M. Brown and Véronique Gouverneur
Organometallics, 2012, 31 (4), 1408-1416

121 Transition Metal Catalysis and Nucleophilic Fluorination
Charlotte Hollingworth and Véronique Gouverneur
Chem. Commun. 2012, 48, 2929-2942

120 Supported Synthesis of Halogenated Organic Compounds
Sophie Boldon, Ida S. R. Stenhagen, Jane E. Moore, Sajinder K. Luthra, Véronique Gouverneur
Synthesis 2011, 24, 3929-3953

119 Organocatalyzed Enantioselective Fluorocyclization
Oscar Lozano, George Blessley, Teresa Martinez del Campo, Amber L. Thompson, Guy T. Giuffredi, Michela Bettati, Matthew Walker, Richard Borman, Véronique Gouverneur
Angew. Chem. Int. Ed. 2011, 50, 8105-8109

118 Facile Synthesis of 4-Deoxy-4-fluoro-<alpha>-D-talopyranoside, 4-Deoxy-4-fluoro-<alpha>-D-idopyranoside and 2,4-Dideoxy-2,4-difluoro-alpha-D-talopyranoside
Guy T. Giuffredi, Laura E. Jennings, Bruno Bernet and Véronique Gouverneur
J. Fluorine Chem. 2011, 132, 772-778 (Special Issue in honor of Alain Tressaud)

117 De Novo Synthesis of 4-Deoxy-4,4-Difluoro- and 2,4-Dideoxy-2,4,4-Trifluoro-Hexosides
Guy T. Giuffredi, Bruno Bernet and Véronique Gouverneur
Eur. J. Org. Chem. 2011, 3825-3836 (Special Issue Women in Chemistry)

116 AuI/AuIII Catalysis: An Alternative Approach for C-C Oxidative Coupling
Matthew N. Hopkinson, Antony D. Gee, Véronique. Gouverneur
Chem. Eur. J. 2011, 17, 8248-8262

115 Palladium-Catalyzed Allylic Fluorination
C. Hollingworth, A. Hazari, M. N. Hopkinson, M. Tredwell, E. Benedetto, M. Huiban, A. D. Gee, J. M. Brown and V. Gouverneur
Angew. Chem. Int. Ed. 2011, 50, 2613-2617. HOT Paper

114 Convergent 18F radiosynthesis: A new dimension for radiolabeling
Lei Li, M. N. Hopkinson, R. Leuma Yona, R. Bejot, A. D. Gee and V. Gouverneur
Chem. Sci. 2011, 2, 123-131

113 The Chemoselective One-Step Alkylation and Isolation of Thiophosphorylated Cdk2 Substrates in the Presence of Native Cysteine
S. E. Lee, L. M. Elphick, H. B. Kramer, A. M.E. Jones, E. S. Child, A.a A. Anderson, L. Bonnac, N. Suwaki, B. M. Kessler, V. Gouverneur, D. J. Mann
ChemBioChem. 2011, 12, 633-640

112 The Traceless Staudinger Ligation for Indirect 18F-Radiolabelling
L. Carroll, S. Boldon, R. Bejot, J. E. Moore, J. Declerck and V. Gouverneur
Org. Biomol. Chem. 2011, 9 (1), 136-140 HOT paper

111 Batch-mode microfluidic radiosynthesis of N-succinimidyl-4-[18F] fluorobenzoate for protein labeling
Romain Bejot, Akradij M. Elizarov, Carroll Ball, Jianzhong Zhang, Reza Miraghaie, Hartmuth C. Kolb, Véronique Gouverneur
J. Labelled Compounds and Radiopharmaceuticals 2011, 54, 117-122

110 Hypoxia Imaging Using PET and SPECT; The Effects of Anesthetic and Carrier Gas on [Cu-64]-ATSM, [(99)mTc-HL91 and [F-18]-FMISO Tumor Hypoxia Accumulation
V. Keersemans, B. cornelissen, R. Hueting, M. Tredwell, J. Dilworth, V. Gouverneur, R. J. Muschel, S. C. Smart
PLOS One 2011, 6, Article Number: e25911 DOI: 10.1371/journal.pone.0025911

109 Hypoxia imaging Agents – bis(thiosemicarbazones) beyond the parent Cu(ATSM)
R. Huting, V. Keersemans, M. Tredwell, M. Christlieb, V. Gouverneur, J. Dilworth
Nuclear Medicine and Biology 2010, 37(6), 695-696

108 Gold Catalysis and Fluorine
M. N. Hopkinson, A. D. Gee and V. Gouverneur
Isr. J. Chem. 2010, 50, 675-690

107 Gold-Catalyzed Cascade Cyclization-Oxidative Alkynylation of Allenoates
M. Hopkinson, J. Ross, G. Giuffredi, A. D. Gee and V. Gouverneur
Org. Lett. 2010, 12 (21), 4904-4907

106 Catalytic Enantioselective Synthesis of P-Stereogenic Compounds
J. S. Harvey, V. Gouverneur
Chem. Comm. 2010, 46, 7477-7485 (Feature Article)

105 Radiosynthesis and Evaluation of [18F]Selectfluor bis(triflate)
H. Teare, E.G. Robins, A. Kirjavainen, S. Forsback, G. Sandford, O. Solin, S. K. Luthra, V. Gouverneur
Angew. Chem. Int. Ed. 2010, 49, 6821-6824 HOT Paper

104 Gold-Catalyzed Diastereoselective Synthesis of α-Fluoroenones from Propargyl Acetates
Matthew N. Hopkinson, Guy T. Giuffredi, Antony D. Gee and Véronique Gouverneur
Synlett 2010, 18, 2737-2742

103 Bis(thiosemicarbazones) as bifunctional chelators for the room temperature labelling of peptides and proteins
R. Hueting, M. Christlieb, J. R Dilworth, E. García Garayoa, V. Gouverneur, M. W. Jones, V. Maes, R.Schibli, X. Sun, and D. A. Tourwé
Dalton Transactions 2010, 39, 3620-3632 HOT Paper

102 Synthesis and O-Phosphorylation of 3,3,4,4-Tetrafluoro-Aryl-C-Nucleoside Analogues
Laurent Bonnac, Sarah E. Lee, Guy T. Giuffredi, Lucy M. Elphick, Alexandra A. Anderson, Emma S. Child, David J. Mann and Véronique Gouverneur
Org. Biomol. Chem. 2010, 8, 1445-1454

101 Diastereoselective Synthesis of P-Stereogenic Heterocycles via Enyne Ring-Closing Metathesis
James Stephen Harvey, Guy T. Giuffredi and Veronique Gouverneur
Org. Lett. 2010, 12, 1236-1239

100 Catalytic activation of hydrogen, silicon, and fluorine by transition-metal complexes
Rauf W, Hazari A, Gouverneur V.
Pure and Applied Chemistry 2010, 82, 1415-1428

99 Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [F-18]FMISO as hypoxia-selective tracer for PET
Bejot R, Kersemans V, Kelly C, Carroll L, King R. C., Gouverneur, V.
Nuclear Medicine and Biology 2010 37, 565-575

98 Syntheses of Mono-, Di-, and Trifluorinated Styrenic Monomers
Walkowiak J, del Campo TM, Ameduri B, Gouverneur, V.
Synthesis 2010 11, 1883-1890

97 Orthogonal F-18 and Cu-64 labelling of functionalised bis(thiosemicarbazonato) complexes
L. Carroll, R. Bejot, R. Hueting, V. Gouverneur
Chem. Commun. 2010 46, 4052-4054 Cover

96 Gold-Catalyzed Intramolecular Oxidative Cross-Coupling of Nonactivated Arenes
M. N. Hopkinson, A. Tessier,A. Salisbury, V. Gouverneur
Chem. A Eur. Journal 2010 16, 4739-4743

95 Transition-Metal-Mediated Reactions for C(sp2)–F Bond Construction: the State of Play
J. M. Brown, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 8610-8614

94 A New departure in Fluorination Chemistry
V. Gouverneur
Science 2009 325, 1630-1631

93 Recent Progress in the use of Fluoroorganic Compounds in Pericyclic Reactions
Y-h. Lam, S. J. Stanway, V. Gouverneur
Tetrahedron 2009, 65 9905-9933

92 Electrophilic Fluorocyclization of Allyl Silanes
S. C. Wilkinson, O. Lozano, M. Schuler, M. Pacheco, R. Salmon, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 7083-7086

91 Oxidative Detagging of Fluorous Organosilanes
S. Boldon, J. E. Moore, V. Gouverneur
J. Fluor. Chem. 2009, 130, 1151-1156 (By Invitation - Issue to celebrate the International Conference on Fluorine Chemistry ’09, Kyoto)

90 Developments in Fluorocyclization Methodologies
S. C. Wilkinson, R. Salmon, V. Gouverneur
Future Med. Chem. 2009, 1 (5), 847-863 (Special Focus: Fluorine in Medicinal Chemistry - By Invitation)

89 Exploring the Roles of Protein Kinases Using Chemical Genetics
L. M. Elphick, S. E. Lee, A. A. Anderson, E. S. Child, L. Bonnac, V. Gouverneur, D. J. Mann
Future Med. Chem. 2009, 1 (7), 1233 (By Invitation)

88 A Quantitative Comparison of Wild Type and Gatekeeper Mutant Cdk2 for Chemical Genetic Studies with ATP Analogues
L. M. Elphick, S. E. Lee, E. S. Child, A. Prasad, C. Pignocchi, S. Thibaudeau, A. A. Anderson, L. Bonnac, V. Gouverneur, D. J. Mann
ChemBioChem. 2009, 10, 1519-1526

87 Synthesis and Reactivity of Novel g-Phosphate Modified ATP Analogues
S. E. Lee, L. M. Elphick, A. A. Anderson, E. S. Child, D. J. Mann, V. Gouverneur
Bio. Med. Chem. Lett.2009, 19, 3804-3807 (By Invitation)

86 Asymmetric de novo Synthesis of Fluorinated D-Glucitol and D-Mannitol Analogues
G. T. Giuffredi, S. Purser, M. Sawicki, A. L. Thompson, V. Gouverneur
Tetrahedron Asym. 2009, 20, 910-920 (By Invitation)

85 Phosphine-Catalysed Cyclisation of b-Hydroxy-,-Difluoroynones
M. Schuler, A. Monney, V. Gouverneur
Synlett 2009, 11, 1733-1736; highlighted in SYNFACTS (Issue 9, 964)

84 Palladium-Catalyzed Substitution of Allylic Fluorides
A. Hazari, V. Gouverneur, J. M. Brown
Angew. Chem. Int. Ed. 2009, 48, 1296-1299

83 Diels–Alder Exo-Selectivity in Terminal-Substituted Dienes and Dienophiles: Experimental Discoveries and Computational Explanations
Y-h. Lam, P. H-Y. Cheong, J. M. Blasco Mata, S. J. Stanway, V. Gouverneur, K. N. Houk
J. Am. Chem. Soc. 2009, 131, 1947-1957

82 Enantioselective Synthesis of P-Stereogenic Phosphinates and Phosphine Oxides by Mo-Catalyzed Asymmetric Ring-Closing Metathesis
J. S. Harvey, S. J. Malcolmson, K. S. Dunne, S. J. Meek, A. L. Thompson, R. R. Schrock, A. H. Hoveyda, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 762-766; highlighted in SYNFACTS (Issue 4, 397)

81 Fluorous Synthesis of 18F-Radiotracers with [18F] Fluoride ion: Nucleophilic Fluorination as the Detagging Process
R. Bejot, T. Fowler, L. Carroll, S. Boldon, J. E. Moore, J. Declerck, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 586-589

80 A Two-Directional Approach to Enantiopure 1,4-Difluoro-Cyclohexenes: Synthesis of Difluorinated Cyclitol Analogues
S. Purser, T. D. W. Claridge, B. Odell, P. R. Moore, V. Gouverneur
Org. Lett. 2008, 10, 4263-4266

79 Gold(I)-Catalyzed Alkoxyhalogenation of b-Hydroxy-a,a-Difluoroynones
M. Schuler, F. Silva, C. Bobbio, A. Tessier, V. Gouverneur
Angew. Chem. Int. Ed. 2008, 47, 7927-7930

78 Fluorous Synthesis of Allylic Fluorides: C–F bond Formation as the Detagging Process
S. Boldon, J. E. Moore, V. Gouverneur
Chem. Commun. 2008, 31, 3622-3624

77 The Chemistry of Propargylic and Allylic Fluorides
M. Pacheco, S.Purser, V. Gouverneur
Chem. Rev. 2008, 108, 1943-1981

76 First Examples of Molecularly Imprinted Nanogels with Aldolase Type I Activity 

D. Carboni, K. Flavin, A. Servant, V. Gouverneur, M. Resmini
Chem. Eur. J. 2008, 14, 7059-7065

75 Stereospecific anti SE2' Fluorination of Allenylsilanes: Synthesis of Enantioenriched Propargylic Fluorides

L. Carroll, S. McCullough, T. Rees, T. D. W. Claridge, V. Gouverneur
Org. Biomol. Chem. 2008, 6, 1731-1733

74 Fluorine-Directed Diastereoselective Iodocyclisations

M. Tredwell, J. A. R. Luft, M. Schuler, K. Tenza, K. N. Houk, V. Gouverneur
Angew. Chem. Int. Ed. 2008, 47(2), 357-360 Selected by the Editor as a Hot Article.

73 Fluorine in Medicinal Chemistry
S. Purser, P. R. Moore, S. Swallow and V. Gouverneur
Chem. Soc. Rev. 2008 37, 320-330 (Tutorial Review)

72 Diastereoselective Fluorination of Silylated 1,2-Oxazines to Access Fluorinated N,O-Heterocycles
. Y.-h. Lam, M. N. Hopkinson, S. J. Stanway and V. Gouverneur
Synlett 2007, 19, 3022-3027

71 Single and Double Stereoselective Fluorination of (E)-Allylsilanes
M. Sawicki, A. Kwok, M. Tredwell and V. Gouverneur
Beilstein Journal of Organic Chemistry 2007, 3:34 . [Thematic Issue on Contemporary Organosilicon Chemistry] By Invitation.

70 A Concise Synthesis of Enantioenriched Fluorinated Carbocycles
Y.-h. Lam, C. Bobbio, I. R. Cooper, V. Gouverneur
Angew. Chem. Int. Ed. 2007, 46(27), 5106-5110. Highlighted as a Frontispiece and selected as a SYNFORM story.

69 Kinetics of Radical Copolymerisation of [1-(Fluoromethyl)vinyl]benzene with Chlorotrifluoroethylene 

G. Kostov, M. Tredwell, V. Gouverneur, B. Ameduri
J. Poly. Sci. Part A: Polymer Chem., 2007, 45, 3843-3850

68 Using chemical genetics and ATP analogues to dissect protein kinase function
L. M. Elphick, S. E. Lee, V. Gouverneur, D. J. Mann
ACS Chem. Biol. 2007, 2(5), 299-314

67 Synthesis and Reactivity of [18F] N-Fluorobenzenesulfonimide
H. Teare, E. G. Robins, E. Årstad, S. K. Luthra and V. Gouverneur
Chem. Commun. 2007, 23, 2330-2332 [Front Cover]

66 Highly Diastereoselective Electrophilic Fluorination of Cyclic Syn b-Hydroxysilanes
S. Purser, C. Wilson, P. R. Moore, V. Gouverneur
Synlett 2007, 7, 1166-1168

65 A Convergent Approach for the Synthesis of fluorinated Sphingosine Analogues
H. Teare, F. Huguet, M. Tredwell, S. Thibaudeau, S. K. Luthra, V. Gouverneur
Arkivoc 10, 232-244 2007 [commemorative Issue for Professor A. Krief] By Invitation.

64 Enantioselective Organocatalytic Aldol reaction of Ynones and its Synthetic Applications
F. Silva, M. Sawicki, V. Gouverneur
Org. Lett. 2006, 8(23) 5417-5419

63 Pd(II)-Catalysed CascadeWacker-Heck Reaction: Chemoselective Coupling of Two Electron Deficient Reactants
F. Silva, M. Reiter, R. Mills-Webb, M. Sawicki, D. Klär, N. Bensel, A. Wagner, V. Gouverneur
J. Org. Chem. 2006, 71, 8390-8394

62 Homometathesis and Cross-Metathesis Coupling of Phosphino-Borane Templates with Electron-rich and electron-Poor Olefins
K. S. Dunne, S. E. Lee, V. Gouverneur
J. Organometal. Chem. 2006, 691 (24-25), 5246-5259

61 Enantioselective Synthesis of a Key “A Ring” Intermediate for the preparation of 1-alpha-Fluoro Vitamin D3 Analogues
G. Giuffredi, C. Bobbio, V. Gouverneur
J. Org. Chem. 2006, 5361-5364

60 Synthesis and Synthetic Applications of Allylic monofluorides
M. Pacheco, V. Gouverneur
Chemistry Today 2006, 24, 12-16

59 Catalytic Asymmetric Fluorination
C. Bobbio and V. Gouverneur
Org. Biomol. Chem. 2006, 2065-2075 [Inside Cover]

58 Synthesis of Propargylic Fluorides from Allenylsilanes
L. Carroll, L. Garcia, M. C. Pacheco and V. Gouverneur
Chem. Commun. 2006, 39, 4113-4115

57 Sequential Desymmetrization-Fluorination: Enantioselective synthesis of fluorinated Cyclitols
S. Purser, P. Moore and V. Gouverneur
Chemistry A European Journal 2006, 12(36), 9176-9185

56 Intramolecular Hetero-Michael Addition of -Hydroxyenones for the Preparation of Highly Substituted Tetrahydropyranones
M. Reiter, H. Turner, V. Gouverneur
Chemistry A European Journal 2006, 12(27), 7190-7203

55 Electrophilic Fluorination of Organosilanes
M. Tredwell, V. Gouverneur
Org. Biomol. Chem., 2006, 26-32 [Featured in Chemical Science]

54 Diastereoselective Ring-Closing Metathesis: Synthesis of P-Stereogenic Phosphinates from Prochiral Phosphinic Acid Derivatives
K. S. Dunne, F. Bisaro, B. Odell, J-M, Paris, V. Gouverneur
J. Org. Chem. 2005, 10803-10809

53 Elongation of -Hydroxyenones by Cross-Metathesis
F. Silva, V. Gouverneur
Tetrahedron Lett. 2005, 8705-8709

52 Synthesis of Novel Enantiopure Fluorinated Building Blocks from Acyclic Chiral Allylsilanes
M. Tredwell, K. Tenza, M. Pacheco, V. Gouverneur
Org. Lett., 2005, 4495-4497

51 Palladium-Catalyzed Oxidative Cyclizations: Synthesis of Dihydropyranones and Furanones
M. Reiter, H. Turner, R. Mills-Webb, V. Gouverneur
J. Org Chem. 2005, 8478-8485

50 Biocatalytic Approaches to Hetero Diels-Alder Adducts of Carbonyl Compounds
V. Gouverneur, M. Reiter
Chem. Eur. J, 2005, 5806-5815 [Frontispiece]

49 Electrophilic Fluorodesilylation of Allenylmethylsilanes: a Novel Entry to 2-Fluoro-1,3-dienes
M. Pacheco, V. Gouverneur
Org. Lett., 2005, 1267-1270

48 Desymmetrization by Direct Cross-metathesis Producing Hitherto Unreachable P-stereogenic phosphine oxides
Fabrice Bisaro, Veronique Gouverneur
Tetrahedron, 2005, 2395-2400

47 A Catalytic Asymmetric Bioorganic Route to Enantioenriched Tetrahydro- and Dihydropyranones
C. Baker-Glenn, N. Hodnett, M. Reiter, S. Ropp, R. Ancliff, V. Gouverneur
J. Am. Chem. Soc., 2005, 1481-1486

46 A Biocatalytic Route to Enantioenriched Sulfanyl Aldol Products
C. Baker-Glenn, R. Ancliff, V. Gouverneur
Tetrahedron, 2004, 7607-7619

45 Oxidative Cyclization of -Hydroxyenones with Palladium(II): A Novel Entry to 2,3-Dihydro-4H-pyran-4-ones
Maud Reiter, Sandrine Ropp, and Véronique Gouverneur
Org. Lett., 2004, 91 -94

44 Stereoselective Synthesis of Internal Allylic Fluorides
S. Thibaudeau, R. Fuller, V. Gouverneur
Org. Biomol. Chem., 2004, 1110-1112

43 Unusual Reversal of Regioselectivity in Antibody-Mediated Aldol Additions with Unsymmetrical Methyl Ketones
V. Maggiotti, S. Bahmanyar, M. Reiter, M. Resmini, K. N. Houk, V. E. Gouverneur
Tetrahedron, 2004, 619-632

42 Sequential Cross-Metathesis/Electrophilic Fluorodesilylation: a Novel Entry to Functionalized Allylic Fluorides
S. Thibaudeau, V. Gouverneur
Org. Lett., 2003, 4891-4893

41 Synthesis of Unprotected and Borane-Protected Cyclic Phosphines using Ru and Mo based Olefin Metathesis Catalysts
C.A. Slinn, A.J. Redgrave, S.L. Hind, C. Edlin, S.P. Nolan, V.E. Gouverneur
Org. Biomol. Chem., 2003, 3820 - 3825

40 Cross-metathesis, a Versatile Synthetic Methodology for the Construction of Alkenyl Phosphine Oxides and Bis-phosphine Oxides
F. Bisaro, V.E. Gouverneur
Tetrahedron Letters, 2003, 44, 7133-7135

39 Regio- and Enantioselective Synthesis of Allylic Fluorides by Electrophilic Fluorodesilylation of Allylsilanes
B. Greedy, J.-M. Paris, T. Vidal, V. Gouverneur
Angew. Chem. Int. Ed., 2003, 3291-3294

38 Asymmetric Synthesis of Aldol Products Derived from Unsymmetrical Ketones: Assignment of the Absolute Configuration of Antibody Aldol Products
V. Maggiotti, J.-B. Wong, R. Razet, A.R. Cowley, V. Gouverneur
Tetrahedron: Asymmetry, 2002, 13, 1789-1798

37 A New Access to Various Functionalized Trimethylsilyl Substituted Carbo- and Heterocycles
M. Schuman, V. Gouverneur
Tetrahedron Lett., 2002, 43, 3513-3516

36 Unprecedented Regiocontrol using an Aldolase I Antibody
V. Maggiotti, M. Resmini, V. Gouverneur
Angew. Chem. Int. Ed. Engl, 2002, 41, 1012-1015

35 Synthetic Applications of Electrophilic Fluorodesilylation
V. Gouverneur, B. Greedy
Chem. Eur. J., 2002, 8, 766-772 [Frontispiece]

34 Design and Synthesis of Haptens for the Dynamic Kinetic Resolution of Oxazolin-5-ones
A. Briot, M. Bujard, V. Gouverneur, C. Mioskowski
Eur. J. Org. Chem., 2002, 1, 139-144

33 Synthesis of a Novel Diarylphosphinic Acid: a Distorted Ground State Mimic and Transition State Analogue for Amide Hydrolysis
M. Schuman, X. Lopez, M. Karplus, V. Gouverneur
Tetrahedron, 2001, 57, 10299-10307

32 Synthesis of a Novel fused alpha,beta-Bispyrone
M. Smietana, V. Gouverneur, C. Mioskowski
Synlett, 2001, 10, 1547-1649

31 Fluorodesilylation of Alkenyltrimethylsilanes: a New Route to Fluoroalkenes and Difluoromethyl-substituted Amides, Alcohols or Ethers
B. Greedy, V. Gouverneur
Chem. Commun., 2001, 3, 233-234

30 Novel Synthesis of Borane Complexes of Cyclic Phosphine Using Ruthenium-Catalysed Olefin Metathesis
M. Schuman, M. Trevitt, A. Redd, V. Gouverneur
Angew. Chem. Int. Ed. 2000, 2491-2493

29 Improvement in Olefin Metathesis using a New Generation of Ruthenium Catalyst Bearing a Imidazolydene Ligand: Synthesis of Heterocycles
M. Bujard, A. Briot, V. Gouverneur, S. Nolan, C. Mioskowski
Org. Lett., 2000, 11, 1517-1519

28 Ring-Closing Metathesis for the Synthesis of Phosphorus Containing Heterocycles
L. Hetherington, B. Greedy, V. Gouverneur
Tetrahedron, 2000, 56, 2053-2060

27 Nozaki-Hiyama Reactions on Halogenated Allylchromium Reagents, a New Entry for the Preparation of Quaternary Halogenated Carbons
R. Baati, V. Gouverneur, C. Mioskowski
J. Org. Chem., 2000, 65, 1235-1238

26 An Improved Synthesis of Iodohydrins from Alkenes
M. Smietana, V. Gouverneur, C. Mioskowski
Tetrahedron Lett., 2000, 41, 193-196

25 Ring Closing Metathesis of Phenyl-Substituted Dienes
M. Bujard, A. Briot, V. Gouverneur, C. Mioskowski
Tetrahedron Lett., 1999, 40, 8785-8788

24 A New Approach to the Synthesis of Efaroxan
K. Couture, V. Gouverneur, C. Mioskowski
Bioorganic & Medicinal Chemistry, 1999, 9, 3023-3026

23 A Novel Access to Alicyclic Phosphine Oxides via Ring Closing Metathesis
M. Trevitt, V. Gouverneur
Tetrahedron Lett., 1999, 41, 7333-7336

22 An Improved Methodology for the Synthesis of Amidines using Thioimidic Esters
R. Baati, V. Gouverneur, C. Mioskowski
Synthesis, 1999, 6, 927-929

21 A Highly Efficient and Practical Synthesis of Cyclic Phosphinates using Ring-Closing Metathesis
M. Bujard, V. Gouverneur, C. Mioskowski
J. Org. Chem., 1999, 64, 2119-2123

20 A New Approach to the Synthesis of Spirooxazolinones
M. Smietana, V. Gouverneur, C. Mioskowski
Tetrahedron Lett., 1999, 40, 1291-1294

19 New Acylnitroso Compounds for the Asymmetric Oxyamination of Dienes
V. Gouverneur, S. J. McCarthy, D. Belotti, C. Mineur, L. Ghosez
Tetrahedron, 1998, 54, 10537-10554

18 Total Synthesis of Halomon
T. Schlama, R. Baati, V. Gouverneur, A. Valleix, C. Mioskowski, J.P. Falck
Angew. Chem. Int. Ed., 1998, 37, 2085-2087

17 Tetraethylammonium Trichloride, a New and Versatile Reagent for Chlorination and Oxidation
T. Schlama, K. Gabriel, V. Gouverneur, C. Mioskowski
Angew. Chem. Int. Ed., 1997, 36, 2342-2344

16 One-Step Synthesis of Chiral Guanidinium Salts from Phosgeniminium Salts
T. Schlama, V. Gouverneur, A. Valleix, A. Greiner, L. Toupet, C. Mioskowski
J. Org. Chem., 1997, 62, 4200-4202

15 One-Step Conversion of Protected Alcohols into Alkyl Halides using Dimethylphosgeniminium Salt
T. Schlama, V. Gouverneur, C. Mioskowski
Tetrahedron Lett., 1997, 38, 3517-3520

14 A new and Efficient Preparation of Carbodiimides from Ureas Using Dimethylphosgeniminium Chloride as a Dehydrating Agent
T. Schlama, V. Gouverneur, C. Mioskowski
Tetrahedron Lett., 1996, 37, 7047-7048

13 N-Hydroxy-Amino Phosphonate Derivatives as Potential Haptens For Eliciting Catalytic Antibodies
V. Gouverneur, M-N. Lalloz
Tetrahedron Lett., 1996, 37 , 6331-6334

12 X-Ray Structure of N-(1'S-hydroxy-4'R-cyclohex-2'-en)-2,5-bis(methoxymethyl)-pyrrolidino carboxamide
J. P. Declercq, V. Gouverneur
Bull. Soc. Chim. Belg., 1996, 6, 359

11 X-Ray Structure of trans-(2,5)-bis(methoxymethyl)pyrrolidinocarbohydroxamic acid
B. Tinant, J. P. Declercq, V. Gouverneur
Bull. Soc. Chim. Belg., 1996, 4, 185

10 X-Ray Structure of 3-(3',4'-dimethoxy)-2,6-triphenyl-1-oxa-2,5-diaza-4-oxo-cyclohexane
B. Tinant, J. Feneau-Dupont, J. P. Declercq, V. Gouverneur
Bull. Soc. Chim. Belg., 1996, 4, 215

9 Electrophilic Amination of 2-Aza-1,3-Dienes
V. Gouverneur, L. Ghosez
Tetrahedron, 1996, 7585-7598

8 Synthesis and Structural Studies of 2-Aza-1,3-Dienes
L. Ghosez, P. Bayard, P. Nshimyumukiza, V. Gouverneur, F. Sainte, R. Beaudegnies, A. M. Frisque-Hesbain, C. Wynants
Tetrahedron, 1995, 51, 11021

7 Antibody Catalysis of Disfavored Diels-Alder Reaction, Control of the Exo and Endo Pathways of the Diels-Alder Reaction by Antibody Catalysis
V.E. Gouverneur, K.N. Houk, B.D. Pascual-Teresa, B. Beno, K.D. Janda, R.A. Lerner; Condensation and Commentary by Carlo Scolastico and Anna Bernardi
Chemtracts -Organic Chemistry 1993, 6, 292-295

6 Control of the exo and endo Pathways of the Diels-Alder Reaction by Antibody Catalysis
V.E. Gouverneur, K.N. Houk, B. de Pascual-Teresa, B. Beno, K.D. Janda, R.A. Lerner
Science, 1993, 262, 204-208

5 Chiral Amides in Asymmetric Synthesis
L. Ghosez, C. Genicot, V. Gouverneur
Pure&Appl. Chem., 1992, 64, 1849-1856

4 Asymmetric Diels-Alder Reactions of a Nitroso Compound derived from D-Bornane-10,2-Sultam
V. Gouverneur, G. Dive, L. Ghosez, Tetrahedron Asymmetry, 1991, 2, 1173-1176

3 Asymmetric Amination of Carboxylic Acids via a Diels-Alder Strategy
V. Gouverneur, L. Ghosez
Tetrahedron Lett., 1991, 32, 5349-5352

2 Stereoselective Diels-Alder Reactions of a new Chiral Carbamoyl Nitroso Compound
V. Gouverneur, L. Ghosez
Tetrahedron Asymmetry, 1990, 1, 363-366

1 Synthesis and Reactions of 3-Alkoxy-2H-Azirines
L. Ghosez, F. Sainte, M. Rivera, C. Bernard-Henriet, V. Gouverneur
Recl. Trav. Chim. Pays-Bas 1986, 456-460