Part II Students

Samantha D. McCullough (New College) who worked under the supervision of Dr V Gouverneur [Synthesis of Enantioenriched Propargylic Fluorides] was the winner [joint prize] of "The Bannister Trust Prize" for the best Part II thesis in June 2007.

Part II projects are available in the following areas:

Fluorine Chemistry {synthesis, drug discovery and imaging}

If you have any further queries, contact Veronique by email


Selected recent publications and Abstracts of Papers (ACS meetings) co-authored by Part II students:

Fluorous Synthesis of 18F-Radiotracers with [18F] Fluoride ion: Nucleophilic Fluorination as the Detagging Process
R. Bejot, T. Fowler, L. Carroll, S. Boldon, J. E. Moore, J. Declerck, V. Gouverneur
Angew. Chem. Int. Ed. 2008, 48, 586-589

Stereospecific anti SE2' Fluorination of Allenylsilanes: Synthesis of Enantioenriched Propargylic Fluorides
L. Carroll, S. McCullough, T. Rees, T. D. W. Claridge, V. Gouverneur
Org. Biomol. Chem. 2008, 6, 1731-1733

Single and Double Stereoselective Fluorination of (E)-Allylsilanes
M. Sawichi, A. Kwok, M. Tredwell, V. Gouverneur
Beil. J. Org. Chem. 2007, Accepted for publication

Diastereoselective Fluorination of Silylated 1,2-Oxazines to Access Fluorinated N.O-Heterocycles
Y.-h. Lam, M. N. Hopkinson, S. J. Stanway, V. Gouverneur
Synlett 2007, 19, 3022-3026

Highly Diastereoselective Electrophilic Fluorination of Cyclic Syn b-Hydroxysilanes
S. Purser, C. Wilson, P. R. Moore, V. Gouverneur
Synlett. 2007, 7,1166-1168

Pd(II)-Catalyzed Cascade Wacker-Heck Reaction: Chemoselective Coupling of Two Electron Deficient Reactants
F. Silva, M. Reiter, R. Mills-Webb, M. Sawicki, D. Klär, N. Bensel, A. Wagner, V. Gouverneur
J. Org. Chem. 2006, 71, 8390-8394

Synthesis of Propargylic Fluorides from Allenylsilanes
L. Carroll, M. Pacheco, L. Garcia, V. Gouverneur
Chem. Commun, 2006, 4113-4115

Intramolecular Hetero-Michael Addition of b-Hydroxyenones for the Preparation of Highly Substituted Tetrahydropyranones
M. Reiter, H. Turner, V. Gouverneur
Chem. Eur. J, 2006, 7190-7203

Palladium-Catalyzed Oxidative Cyclizations: Synthesis of Dihydropyranones and Furanones
M. Reiter, H. Turner, R. Mills-Webb, V. Gouverneur,
J. Org Chem. 2005, 8478-8485

Silylated allenes as percusors of fluorinated dienes and propargylic fluorides
M. Carmen Pacheco, L. Garcia, V. Gouverneur,
Abstracts of Papers, 230th ACS National Meeting, August 28-September 1, 2005

Electrophilic fluorocyclization vs. electrophilic fluorodesilylation
M. Carmen Pacheco, S. Wilkinson, V. Gouverneur,
Abstracts of Papers, 230th ACS National Meeting, August 28-September 1, 2005

Stereoselective Synthesis of Internal Allylic Fluorides
S. Thibaudeau, R. Fuller, V. Gouverneur,
Org. Biomol. Chem, 2004, 1110-1112

Asymmetric synthesis of aldol products derived from unsymmetrical ketones: assignment of the absolute configuration of antibody aldol products
V. Maggiotti, J.-B. Wong, R. Razet, A.R. Cowley, V. Gouverneur,
Tetrahedron: Asym, 2002, 13, 1789-1798

Novel Synthesis of Borane Complexes of Cyclic Phosphine Using Ruthenium-Catalysed Olefin Metathesis
M. Schuman, M. Trevitt, A. Redd, V. Gouverneur,
Angew. Chem. Int. Engl. 2000, 2491-2493

Ring-Closing Metathesis for the Synthesis of Phosphorus Containing Heterocycles
L. Hetherington, B. Greedy, V. Gouverneur,
Tetrahedron2000, 56, 2053-2060

A Novel Access to Alicyclic Phosphine Oxides via Ring Closing Metathesis
M. Trevitt, V. Gouverneur,
Tetrahedron Lett, 1999, 41, 7333-7336