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Dr. Folorunsho Bright Omage

Computational Biologist & Visiting Researcher · University of Oxford

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Visiting Researcher
University of Oxford · Dept. of Computer Science, UK
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Post-doctoral Researcher
University of Campinas · UNICAMP, Brazil
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Research Fellow
EMBRAPA Digital Agriculture, Brazil
Dr. Folorunsho Bright Omage
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Bridging Computation
and Molecular Biology

I am a Visiting Researcher at the University of Oxford, Department of Computer Science, hosted by Prof. Peter Minary (Wolfson Building, Parks Road). Concurrently, I hold a position as Post-doctoral Research Scientist at UNICAMP (University of Campinas), Instituto de Química, Brazil, under Prof. Ljubica Tasic, and serve as a Research Fellow at EMBRAPA Digital Agriculture under Prof. Goran Neshich.

My research sits at the convergence of computational biology, machine learning, and structural bioinformatics. I develop deep learning and graph neural network frameworks to tackle fundamental problems in genomic medicine — chief among them the accurate prediction of CRISPR-Cas9 off-target cleavage, a critical bottleneck in the safe clinical application of gene editing.

My work spans allosteric site prediction (STINGAllo), metabolomics, drug discovery, and global burden of disease studies — all unified by a single philosophy: rigorous methodology, domain depth, and results that are reproducible and clinically meaningful.

Oxford
Visiting Researcher
University of Oxford
Dept. of Computer Science · UK
Host: Prof. Peter Minary
UNICAMP
Post-doctoral Researcher
University of Campinas (UNICAMP)
Instituto de Química · Brazil
Supervisor: Prof. Ljubica Tasic
EMBRAPA
Research Fellow
EMBRAPA Digital Agriculture
Digital Agriculture · Brazil
Supervisor: Prof. Goran Neshich

Six Research Themes,
One Mission

Making computational tools that translate directly into biological insight and clinical impact.

01

CRISPR-Cas9 Off-Target Prediction

Deep learning and GNN models predicting unintended cleavage sites — enabling safer gene editing therapeutics.

02

Structural Bioinformatics & STINGAllo

STING descriptors, STINGAllo web server, and MRND — characterising protein allosteric sites and structure-function relationships at atomic resolution.

03

Graph Neural Networks

GNN architectures for molecular graphs — representation learning over atoms, bonds, and residue interaction networks for property prediction.

04

Computational Drug Discovery

ML-driven virtual screening, molecular docking, and ADMET prediction — from SARS-CoV-2 protease inhibitors to antifungal and antiretroviral compounds.

05

Metabolomics & NMR

NMR-based metabolomic profiling with ML for biomarker discovery — including mercury-selenium interactions, obesity lipid markers, and diabetes metabolic signatures.

06

Global Burden of Disease

Systematic analyses of disease burden across 204 countries — cardiovascular disease, cancer, childhood vaccination, and cause-of-death data in collaboration with international consortia.

Selected Works

38 peer-reviewed publications · 942 citations · h-index 13 · i10-index 13. Full list: Google Scholar · ORCID

2026
Artificial Intelligence in the Life Sciences · Elsevier

Protein family membership governs exosite predictability across the structural proteome

IH Yano, I Mazoni, JH Yano, G Neshich — 2026
View →
2025
Computational and Structural Biotechnology Journal · Elsevier

Protein allosteric site identification using machine learning and per amino acid residue reported internal protein nanoenvironment descriptors

FB Omage, JA Salim, I Mazoni, IH Yano, L Borro, JEH González — 8 citations
View →
2025
Briefings in Bioinformatics · Oxford Academic

STINGAllo: a web server for high-throughput prediction of allosteric site-forming residues using internal protein nanoenvironment descriptors

FB Omage, JA Salim, I Mazoni, IH Yano, JEH Hernández González — 3 citations
View →
2025
Scientific Reports · Nature

Experimental and computational insights into the therapeutic mechanisms of resveratrol in a Drosophila α-synuclein model of Parkinson's disease

AO Abolaji, AO Adedara, JC Madu, OT Owalude, OM Ogunyemi, FB Omage — 6 citations
View →
2025
Environmental Pollution · Elsevier

Unraveling mercury-selenium interactions through metabolomics: Impacts on riverside communities in the Amazon

JG de Moraes Pontes, BA Rocha, JC Cruz, GN Cezarette, FB Omage — 3 citations
View →
2023
Journal of Chemical Information and Modeling · ACS

Diphenyl Diselenide and SARS-CoV-2: in silico Exploration of the Mechanisms of Inhibition of Main Protease (Mpro) and Papain-like Protease (PLpro)

FB Omage, A Madabeni, AR Tucci — DOI: 10.1021/acs.jcim.3c00168 · 26 citations
View →
2023
Scientific Reports · Nature

Plasma lipid metabolites as potential biomarkers for identifying individuals at risk of obesity-induced metabolic complications

PENR Bellot, ES Braga, FB Omage — 16 citations
View →
2021
Molecular · Wiley Online Library

In silico Studies on the Interaction between Mpro and PLpro From SARS-CoV-2 and Ebselen, its Metabolites and Derivatives

PA Nogara, FB Omage, GR Bolzan — 46 citations
View →
2021
Applied Sciences · MDPI

Mechanistic Insight into SARS-CoV-2 Mpro Inhibition by Organoselenides: The Ebselen Case Study

A Madabeni, PA Nogara, FB Omage, JBT Rocha — 25 citations
View →
+29

29 additional publications including Global Burden of Disease studies (The Lancet), chalcogenium chemistry, NMR metabolomics, and antifungal/antiretroviral drug design. View all 38 on Google Scholar →

Technical Arsenal

Machine Learning & AI

PyTorch / Deep Learning
Graph Neural Networks (GNN)
Transformers / Attention Models
Scikit-learn / XGBoost / Random Forest
CNN / RNN / LSTM

Structural Bioinformatics

Protein Structure Analysis (PDB)
STING / STINGAllo / MRND Descriptors
Allosteric Site Prediction
CRISPR-Cas9 Off-Target Analysis
Sequence Alignment / Biopython

Computational Chemistry

Molecular Docking (AutoDock, Glide)
Virtual Screening Pipelines
ADMET Property Prediction
RDKit / Cheminformatics
MD Simulations (GROMACS/AMBER)

Programming & HPC

Python (NumPy, Pandas, SciPy)
R / MATLAB / Julia
Bash / Linux / SLURM / HPC
Git / Docker / Singularity
Jupyter / Streamlit / Flask

Metabolomics & NMR

¹H-NMR Metabolomics
Multivariate Statistical Analysis (PCA, PLS-DA)
Biomarker Discovery
MetaboAnalyst / HMDB Annotation
LC-MS / GC-MS Data Analysis

Scientific Communication

Peer-reviewed Publication Writing
Grant & Research Proposal Writing
International Conference Presentation
Data Visualisation (Matplotlib, Seaborn, ggplot)
LaTeX / Overleaf

Let's Collaborate

Open to research collaborations, academic enquiries, and scientific discussions.

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Oxford Office

Wolfson Building, Parks Road
Oxford OX1 3QD, UK

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ORCID

0000-0002-9750-5034
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Google Scholar

942 citations · h-index 13