Tutorials in Cell Biology and Anatomy

 

Essay

To what extent is cell polarity: a) a unique property of epithelial cells, and b) the most important property (amongst the whole range of specializations) of these cells.

 

References

1.       Trends in Cell Biology 1997, Volume 7, page 393

2.       The origins of cell polarity. Cell, 1996, 84, 335-344

3.       Protein trafficking in the exocytotic pathway of polarized epithelial cells. Trends in cell biology, 2001, 11, 483-486 http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCX-44FBS2J-R&_coverDate=12%2F01%2F2001&_alid=61551117&_rdoc=1&_fmt=summary&_orig=search&_qd=1&_cdi=5182&_sort=d&_acct=C000010360&_version=1&_urlVersion=0&_userid=126524&md5=041bdd31b310d5ffbd752f1938040ee4

4.       New perspectives on mechanisms involved in generating epithelial cell polarity. Physiological Reviews, 1999, 79, 73-98 http://physrev.physiology.org/cgi/content/full/79/1/73

5.       Genetic control of epithelial cell polarity: lessons from Drosophila. Developmental Dynamics 2000, 218:52-67. Also available on line at:  http://www3.interscience.wiley.com/cgi-bin/fulltext/72502442/FILE?TPL=ftx_start

6.       Regulation of gene expression in developing epidermal epithelia. Bioessays. 1997;19:691-8

7.       Epithelial cell polarity and disease. Am J Physiol. 1997; 272:F434-42

8.       Epithelial sodium channels: function, structure, and regulation. Physiol Rev. 1997; 77:359-96

 

 

Web resources

Nature focus on membrane traffic at: http://www.nature.com/ncb/focus/membrane/

Nature focus on signaling and adhesion at: http://www.nature.com/ncb/focus/signallingadhesion/

 

 

mjaw

25.x.2005