Publications

Click here for a list of our publication documents that we have for download from this site.

1.
J. J. Tao, P. Castel, N. Radosevic-Robin, M. Elkabets, N. Auricchio, N. Aceto, G. Weitsman, P. Barber, B. Vojnovic, H. Ellis, N. Morse, N. T. Viola-Villegas, A. Bosch, D. Juric, S. Hazra, S. Singh, P. Kim, A. Bergamaschi, S. Maheswaran, T. Ng, F. Penault-Llorca, J. S. Lewis, L. A. Carey, C. M. Perou, J. Baselga, and M. Scaltriti, "Antagonism of EGFR and HER3 Enhances the Response to Inhibitors of the PI3K-Akt Pathway in Triple-Negative Breast Cancer," Sci. Signal. 7, ra29 (2014).
2.
P. R. Barber, I. D. C. Tullis, M. I. Rowley, C. D. Martins, G. Weitsman, K. Lawler, M. Coffey, N. Woodman, C. E. Gillett, T. Ng, and B. Vojnovic, "The Gray Institute open microscopes applied to radiobiology and protein interaction studies," Proc. SPIE 8949, 89490D–89490D–17 (2014).
3.
P. A. Young, A. Grislis, P. R. Barber, P. J. Keely, and K. W. Eliceiri, "Data Processing for Time-Domain Fluorescence Lifetime Imaging Microscopy," Microscopy and Microanalysis 19, 758–759 (2013).
4.
K. J. Peach, M. Aslaninejad, R. J. Barlow, C. D. Beard, N. Bliss, J. H. Cobb, M. J. Easton, T. R. Edgecock, R. Fenning, I. S. K. Gardner, M. A. Hill, H. L. Owen, C. J. Johnstone, B. Jones, T. Jones, D. J. Kelliher, A. Khan, S. Machida, P. A. McIntosh, S. Pattalwar, J. Pasternak, J. Pozimski, C. R. Prior, J. Rochford, C. T. Rogers, R. Seviour, S. L. Sheehy, S. L. Smith, J. Strachan, S. Tygier, B. Vojnovic, P. Wilson, H. Witte, and T. Yokoi, "Conceptual design of a nonscaling fixed field alternating gradient accelerator for protons and carbon ions for charged particle therapy," Phys. Rev. ST Accel. Beams 16, 030101 (2013).
5.
J. C. G. Jeynes, M. J. Merchant, L. Barazzuol, M. Barry, D. Guest, V. V. Palitsin, G. W. Grime, I. D. C. Tullis, P. R. Barber, B. Vojnovic, and K. J. Kirkby, "“Broadbeam” irradiation of mammalian cells using a vertical microbeam facility," Radiat Environ Biophys 52, 513–521 (2013).
6.
V. Devauges, E. Ortiz-Zapater, C. Efthymiou, M. Keppler, J. Barbeau, D. R. Matthews, J. M. O. Pitmilly, P. R. Barber, D. Rolfe, T. Ng, and S. M. Ameer-Beg, "Single Molecule FRET using the FRET pair DRONPA/PhotoActivable mCherry," in Single Molecule Spectroscopy and Superresolution Imaging Vi, J. Enderlein, I. Gregor, Z. K. Gryczynski, R. Erdmann, and F. Koberling, eds. (Spie-Int Soc Optical Engineering, 2013), Vol. 8590, p. 85900A.
7.
P. R. Barber, I. D. C. Tullis, G. P. Pierce, R. G. Newman, J. Prentice, M. I. Rowley, D. R. Matthews, S. M. Ameer-Beg, and B. Vojnovic, "The Gray Institute “open” high-content, fluorescence lifetime microscopes," J. Microscopy 251, 154–67 (2013).
8.
S. Akerman, M. Fisher, R. A. Daniel, D. Lefley, C. C. Reyes-Aldasoro, S. J. Lunt, S. Harris, M. Bjorndahl, L. J. Williams, H. Evans, P. R. Barber, V. E. Prise, B. Vojnovic, C. Kanthou, and G. M. Tozer, "Influence of soluble or matrix-bound isoforms of vascular endothelial growth factor-a on tumor response to vascular-targeted strategies," International Journal of Cancer n/a–n/a (2013).
9.
P. Wilson, B. Jones, T. Yokoi, M. Hill, and B. Vojnovic, "Revisiting the Ultra‐High Dose Rate Effect: Implications for Charged Particle Radiotherapy Using Protons and Light Ions," The British Journal of Radiology (2012).
10.
M. R. L. Stratford and L. K. Folkes, "A validated HPLC method with fluorescence detection for the glucuronides of Combretastatin A1 in human plasma, and studies on their cis–trans isomerisation," J. Pharmaceut. Biomed. 62, 114–118 (2012).
11.
M. R. L. Stratford and L. K. Folkes, "Quantitative determination of the anticancer prodrug combretastatin A1 phosphate (OXi4503, CA1P), the active CA1 and its glucuronide metabolites in human urine and of CA1 in plasma by HPLC with mass spectrometric detection," J. Chromatogr. B in press, (2012).
12.
K. Rothkamm, J. C. Crosbie, F. Daley, S. Bourne, P. R. Barber, B. Vojnovic, L. Cann, and P. A. W. Rogers, "In situ Biological Dose Mapping Estimates the Radiation Burden Delivered to “Spared” Tissue between Synchrotron X-Ray Microbeam Radiotherapy Tracks," PLoS ONE 7, e29853 (2012).
13.
D. M. Patterson, M. Zweifel, M. R. Middleton, P. M. Price, L. K. Folkes, M. R. L. Stratford, P. Ross, S. Halford, J. Peters, J. Balkissoon, D. J. Chaplin, A. R. Padhani, and G. J. S. Rustin, "Phase I Clinical and Pharmacokinetic Evaluation of the Vascular-Disrupting Agent OXi4503 in Patients with Advanced Solid Tumors," Clin Cancer Res 18, 1415–1425 (2012).
14.
M. J. Merchant, J. C. G. Jeynes, G. W. Grime, V. Palitsin, I. D. C. Tullis, P. R. Barber, B. Vojnovic, R. P. Webb, and K. J. Kirkby, "A focused scanning vertical beam for charged particle irradiation of living cells with single counted particles," Rad. Res. 178, 182–190 (2012).
15.
D. R. Matthews, G. O. Fruhwirth, G. Weitsman, L. M. Carlin, E. Ofo, M. Keppler, P. R. Barber, I. D. C. Tullis, B. Vojnovic, T. Ng, and S. M. Ameer-Beg, "A Multi-Functional Imaging Approach to High-Content Protein Interaction Screening," PLoS ONE 7, e33231 (2012).
16.
H. C. Mandeville, Q. S. Ng, F. M. Daley, P. R. Barber, G. Pierce, J. Finch, M. Burke, Mb. Bell, E. R. Townsend, R. Kozarski, B. Vojnovic, P. J. Hoskin, and V. Goh, "Operable Non–Small Cell Lung Cancer: Correlation of Volumetric Helical Dynamic Contrast-Enhanced CT Parameters with Immunohistochemical Markers of Tumor Hypoxia," Radiology (2012).
17.
M. Kelleher*, F. Festy*, P. R. Barber*, E. Shamil, K. Lawler, G. Patel, G. Weitsman, J. Barrett, G. Fruhwirth, L. Huang, I. D. C. Tullis, N. Woodman, S. Pinder, E. Ofo, L. Fernandes, M. Beutler, S. M. Ameer-Beg, S. Irshad, L. Holmberg, J. Condeelis, F. Fraternali, C. E. Gillett, P. A. Ellis, B. Vojnovic, A. Coolen, and T. Ng, "Time dependent breast cancer metastasis prediction using protein interaction imaging combined with Bayesian modelling to reduce overfitting and improve on inter-cohort reproducibility," Submitted to PLoS Medicine (2012).
18.
M. Baker, S. D. Robinson, T. Lechertier, P. R. Barber, B. Tavora, G. D’Amico, D. T. Jones, B. Vojnovic, and K. Hodivala-Dilke, "Use of the mouse aortic ring assay to study angiogenesis," Nat. Protocols 7, 89–104 (2012).
19.
B. R. Waterhouse, M. Gijsen, P. R. Barber, I. D. C. Tullis, B. Vojnovic, and A. Kong, "Assessment of EGFR/HER2 dimerization by FRET-FLIM utilizing Alexa-conjugated secondary antibodies in relation to targeted therapies in cancers," Oncotarget 2, 728–736 (2011).
20.
M. R. L. Stratford and L. K. Folkes, "Validation of a method for the determination of the anticancer agent Combretastatin A1 phosphate (CA1P, OXi4503) in human plasma by HPLC with post-column photolysis and fluorescence detection," J. Chromatogr. B 879, 2673–2676 (2011).
21.
M. Rowley, P. R. Barber, A. C. C. Coolen, and B. Vojnovic, "Bayesian analysis of fluorescence lifetime imaging data," Proc. SPIE 7903, 74 (2011).
22.
S. E. Rademakers, P. F. Rijken, W. J. Peeters, M. M. Nijkamp, P. R. Barber, J. Laak, A. J. Kogel, J. Bussink, and J. H. Kaanders, "Parametric mapping of immunohistochemically stained tissue sections; a method to quantify the colocalization of tumor markers," Cell. Oncol. 34, 119–129 (2011).
23.
I. A. Pope, P. R. Barber, S. Horn, E. Ainsbury, K. Rothkamm, and B. Vojnovic, "A portable microfluidic fluorescence spectrometer device for [gamma]-H2AX-based biological dosimetry," Radiat. Meas. 46, 907–911 (2011).
24.
G. S. Patel, T. Kiuchi, K. Lawler, E. Ofo, G. O. Fruhwirth, M. Kelleher, E. Shamil, R. Zhang, P. R. Selvin, G. Santis, J. Spicer, N. Woodman, C. E. Gillett, P. R. Barber, B. Vojnovic, G. Kéri, T. Schaeffter, V. Goh, M. J. O’Doherty, P. A. Ellis, and T. Ng, "The challenges of integrating molecular imaging into the optimization of cancer therapy," Integr. Biol. 3, 603–631 (2011).
25.
H. Milewicz, L. Carlin, L. Fernandes, D. R. Matthews, M. Perani, J. Levitt, M. D. Keppler, T. Coolen, P. R. Barber, B. Vojnovic, K. Suhling, F. Fraternali, S. Ameer-Beg, P. J. Parker, N. S. B. Thomas, and T. Ng, "Application of a new strategy to identify regulators of a signalling pathway in human immune cells," Br. J. Haematol. 153, 19–19 (2011).
26.
G. O. Fruhwirth, L. P. Fernandes, G. Weitsman, G. Patel, M. Kelleher, K. Lawler, A. Brock, S. P. Poland, D. R. Matthews, G. Keri, P. R. Barber, B. Vojnovic, S. M. Ameer-Beg, A. C. C. Coolen, F. Fraternali, and T. Ng, "How Förster Resonance Energy Transfer Imaging Improves the Understanding of Protein Interaction Networks in Cancer Biology," ChemPhysChem 12, 442–461 (2011).
27.
L. K. Folkes, M. Trujillo, S. Bartesaghi, R. Radi, and P. Wardman, "Kinetics of reduction of tyrosine phenoxyl radicals by glutathione," Arch. Biochem. Biophys. 506, 242–249 (2011).
28.
G. Flaccavento, V. Lempitsky, I. Pope, P. R. Barber, A. Zisserman, J. A. Noble, and B. Vojnovic, "Learning to Count Cells: applications to lens-free imaging of large fields," in Proc. MIAAB (2011).
29.
B. Cornelissen, S. Darbar, R. Hernandez, V. Kersemans, I. Tullis, P. R. Barber, S. Smart, B. Vojnovic, R. Reilly, and K. A. Vallis, "ErbB-2 Blockade and Prenyltransferase Inhibition Alter Epidermal Growth Factor and Epidermal Growth Factor Receptor Trafficking and Enhance 111In-DTPA-hEGF Auger Electron Radiation Therapy," J. Nucl. Med. 52, 776 –783 (2011).
30.
L. M. Carlin, R. Evans, H. Milewicz, L. Fernandes, D. R. Matthews, M. Perani, J. Levitt, M. D. Keppler, J. Monypenny, T. Coolen, P. R. Barber, B. Vojnovic, K. Suhling, F. Fraternali, S. Ameer-Beg, P. J. Parker, N. S. B. Thomas, and T. Ng, "A Targeted siRNA Screen Identifies Regulators of Cdc42 Activity at the Natural Killer Cell Immunological Synapse," Sci. Signal. 4, ra81 (2011).
31.
S. Carballal, M. Trujillo, E. Cuevasanta, S. Bartesaghi, M. N. Möller, L. K. Folkes, M. A. García-Bereguiaín, C. Gutiérrez-Merino, P. Wardman, A. Denicola, R. Radi, and B. Alvarez, "Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest," Free Radical Bio. Med. 50, 196–205 (2011).
32.
R. Ali, M. Gooding, T. Szilágyi, B. Vojnovic, M. Christlieb, and M. Brady, "Automatic segmentation of adherent biological cell boundaries and nuclei from brightfield microscopy images," Machine Vision and Applications (2011).
33.
I. M. Pires, Z. Bencokova, M. Milani, L. K. Folkes, J.-L. Li, M. R. Stratford, A. L. Harris, and E. M. Hammond, "Effects of Acute Versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability," Cancer Res 70, 925–935 (2010).
34.
J. Moss, H. Tinline-Purvis, C. A. Walker, L. K. Folkes, M. R. Stratford, J. Hayles, K.-L. Hoe, D.-U. Kim, H.-O. Park, S. E. Kearsey, O. Fleck, C. Holmberg, O. Nielsen, and T. C. Humphrey, "Break-induced ATR and Ddb1–Cul4Cdt2 ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast," Gene. Dev. 24, 2705 –2716 (2010).
35.
D. R. Matthews, L. M. Carlin, E. Ofo, P. R. Barber, B. Vojnovic, M. Irving, T. Ng, and S. M. Ameer-Beg, "Time-lapse FRET microscopy using fluorescence anisotropy," J. Microsc. 237, 51–62 (2010).
36.
E. Favaro, A. Ramachandran, R. McCormick, H. Gee, C. Blancher, M. Crosby, C. Devlin, C. Blick, F. Buffa, J.-L. Li, B. Vojnovic, R. Pires das Neves, P. Glazer, F. Iborra, M. Ivan, J. Ragoussis, and A. Harris, "MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU," PLoS One 5, e10345 (2010).
37.
P. R. Barber, S. M. Ameer-Beg, S. Pathmananthan, M. Rowley, and A. C. C. Coolen, "A Bayesian method for single molecule, fluorescence burst analysis," Biomed. Opt. Express 1, 1148–1158 (2010).
38.
T. Meyer, A. M. Gaya, G. Dancey, M. R. L. Stratford, S. Othman, S. K. Sharma, D. Wellsted, N. J. Taylor, J. J. Stirling, L. Poupard, L. K. Folkes, P.-S. Chan, R. B. Pedley, K. A. Chester, K. Owen, J. A. Violet, A. Malaroda, A. J. Green, J. Buscombe, A. R. Padhani, G. J. Rustin, and R. H. Begent, "A phase I trial of radioimmunotherapy with 131I-A5B7 anti-CEA antibody in combination with combretastatin-A4-phosphate in advanced gastrointestinal carcinomas," Clin. Cancer Res. 15, 4484–4492 (2009).
39.
K. Makrogianneli, L. M. Carlin, M. D. Keppler, D. R. Matthews, E. Ofo, A. Coolen, S. M. Ameer-Beg, P. R. Barber, B. Vojnovic, and T. Ng, "Integrating Receptor Signal Inputs That Influence Small Rho GTPase Activation Dynamics at the Immunological Synapse," Mol Cell Biol 29, 2997–3006 (2009).
40.
M. Kelleher, G. Fruhwirth, G. Patel, E. Ofo, F. Festy, P. Barber, S. Ameer-Beg, B. Vojnovic, C. Gillett, A. Coolen, G. Kéri, P. Ellis, and T. Ng, "The potential of optical proteomic technologies to individualize prognosis and guide rational treatment for cancer patients," Target. Oncol. 4, 235–252 (2009).
41.
L. K. Folkes, K. B. Patel, P. Wardman, and M. Wrona, "Kinetics of reaction of nitrogen dioxide with dihydrorhodamine and the reaction of the dihydrorhodamine radical with oxygen: Implications for quantifying peroxynitrite formation in cells," Arch. Biochem. Biophys. 484, 122–126 (2009).
42.
M. Folkard, K. M. Prise, G. Grime, K. Kirkby, and B. Vojnovic, "The use of microbeams to investigate radiation damage in living cells," Appl. Radiat. Isotopes 67, 436–439 (2009).
43.
G. Flaccavento, M. Folkard, J. A. Noble, K. M. Prise, and B. Vojnovic, "Substrate evaluation for a microbeam endstation using unstained cell imaging," Appl. Radiat. Isotopes 67, 460–463 (2009).
44.
P. R. Barber, S. M. Ameer-Beg, J. Gilbey, L. M. Carlin, M. Keppler, T. C. Ng, and B. Vojnovic, "Multiphoton time-domain FLIM: Practical application to protein-protein interactions using global analysis," J. R. Soc. Interface 6, S93–S105 (2009).
45.
S. Badie, C. Liao, M. Thanasoula, P. Barber, M. A. Hill, and M. Tarsounas, "RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation," J. Cell Biol. 185, 587–600 (2009).
46.
B. Vojnovic, P. R. Barber, I. Pope, P. J. Smith, and R. J. Errington, "Detecting Objects," Patent WO/2008/090330(2008).
47.
G. M. Tozer, S. Akerman, N. A. Cross, P. R. Barber, M. A. Bjorndahl, O. Greco, S. Harris, S. A. Hill, D. J. Honess, C. R. Ireson, K. L. Pettyjohn, V. E. Prise, C. C. Reyes-Aldasoro, C. Ruhrberg, D. T. Shima, and C. Kanthou, "Blood Vessel Maturation and Response to Vascular-Disrupting Therapy in Single Vascular Endothelial Growth Factor-A Isoform-Producing Tumors," Cancer Res. 68, 2301–2311 (2008).
48.
G. M. Tozer, C. Kanthou, G. Lewis, V. E. Prise, B. Vojnovic, and S. A. Hill, "Tumour vascular disrupting agents: combating treatment resistance," Br. J. Radiol. 81, S12–20 (2008).
49.
C. C. Reyes-Aldasoro, I. Wilson, V. E. Prise, P. R. Barber, S. M. Ameer-Beg, B. Vojnovic, V. J. Cunningham, and G. M. Tozer, "Estimation of apparent tumor vascular permeability from multiphoton fluorescence microscopic images of P22 rat sarcomas in vivo," Microcirculation 15, 65 (2008).
50.
D. R. Matthews, S. M. Ameer-Beg, P. Barber, G. P. Pierce, R. G. Newman, B. Vojnovic, L. M. Carlin, M. D. Keppler, T. Ng, K. Suhling, and M. Irving, "A high-content screening platform utilizing polarization anisotropy and FLIM microscopy," Proc. SPIE 6859, (2008).
51.
E. Madej, L. K. Folkes, P. Wardman, G. Czapski, and S. Goldstein, "Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit," Free Radical Bio. Med. 44, 2013–2018 (2008).
52.
J. A. Levitt, N. Sergent, A. Chauveau, M. K. Kuimova, P. R. Barber, D. M. Davis, and K. Suhling, "Multidimensional multiphoton fluorescence lifetime imaging of cells," Proc. SPIE 6860, (2008).
53.
R. J. Errington, J. Fisher, S. Chappell, M. Wiltshire, P. Barber, B. Vojnovic, and P. J. Smith, "Detection Of Gamma-H2ax Foci Using High Content Screening Formats," In ISAC XXIV 350, 248 (2008).
54.
P. R. Barber, G. P. Pierce, S. M. Ameer-Beg, D. R. Matthews, L. M. Carlin, M. Keppler, M. Kelleher, F. Festy, C. Gillett, R. Springall, T. C. Ng, and B. Vojnovic, "Towards high-throughput FLIM for protein-protein interaction screening of live cells and tissue microarrays," in 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI ’08) (2008), pp. 356–359.
55.
P. Wardman, K. Rothkamm, L. K. Folkes, M. Woodcock, and P. J. Johnston, "Radiosensitization by Nitric Oxide at Low Radiation Doses," Radiation Research 167, 475–484 (2007).
56.
S. Prag, M. Parsons, M. D. Keppler, S. M. Ameer-Beg, P. Barber, J. Hunt, A. J. Beavil, R. Calvert, M. Arpin, B. Vojnovic, and T. Ng, "Activated Ezrin Promotes Cell Migration through Recruitment of the GEF Dbl to Lipid Rafts and Preferential Downstream Activation of Cdc42," Mol. Biol. Cell 18, 2935–2948 (2007).
57.
I. A. Pope, "A complete, self-contained, optical biochip with live cell imaging," presented at SPIE Photonics West, San Jose, CA, USA (2007).
58.
K. Njoh, P. J. Smith, S. C. Chappell, H. D. Summers, D. Matthews, D. Morris, A. Goater, J. Burt, I. Pope, B. Vojnovic, S. Ameer-Beg, and R. J. Errington, "Live cell tracking on an optical biochip platform," Proc. SPIE 6441, 9 (2007).
59.
Q.-S. Ng, V. Goh, J. Milner, M. R. Stratford, L. K. Folkes, G. M. Tozer, M. I. Saunders, and P. J. Hoskin, "Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study," Lancet Oncol. 8, 111–118 (2007).
60.
D. Morris, A. Goater, A. Menachery, J. Burt, N. Rizvi, H. Matthews, I. Summers, B. Vojnovic, K. Njoh, S. Chappell, R. J. Errington, and P. Smith, "Development of an Optical Biochip for the Analysis of Cell Environment Sensitivity," Proc. SPIE 6441, 64410V (2007).
61.
A. Michette, T. Button, C. Dunare, C. Feldman, M. Folkard, D. Hart, C. McFaul, G. R. Morrison, W. Parkes, S. Pfauntsch, A. K. Powell, D. Rodriguez-Sanmartin, S. Sahraei, T. Stevenson, B. Vojnovic, R. Willingale, and D. Zhang, "Active microstructured arrays for x-ray optics," Proc. SPIE 6705, 670502–1 – 670502–12 (2007).
62.
G. McConnell, J. M. Girkin, S. M. Ameer-Beg, P. R. Barber, B. Vojnovic, T. Ng, A. Banerjee, T. F. Watson, and R. J. Cook, "Time-correlated single-photon counting fluorescence lifetime confocal imaging of decayed and sound dental structures with a white-light supercontinuum source," J. Microsc. 225, 126–136 (2007).
63.
D. R. Matthews, H. D. Summers, K. Njoh, S. Chappell, R. Errington, P. Smith, I. Pope, P. Barber, B. Vojnovic, and S. Ameer-Beg, "A fluorescence biochip with a plasmon active surface," Proc. SPIE 6450, (2007).
64.
L. K. Folkes, M. Christlieb, E. Madej, M. R. L. Stratford, and P. Wardman, "Oxidative Metabolism of Combretastatin A-1 Produces Quinone Intermediates with the Potential To Bind to Nucleophiles and To Enhance Oxidative Stress via Free Radicals," Chem. Res. Toxicol. 20, 1885–1894 (2007).
65.
M. Folkard, K. M. Prise, A. G. Michette, and B. Vojnovic, "The use of radiation microbeams to investigate the bystander effect in cells and tissues," Nucl. Instrum. Meth. A 580, 446–450 (2007).
66.
S. A. Everett, V. M. McErlane, K. F. McLeod, F. M. Daley, P. R. Barber, B. Vojnovic, P. D. Nathan, P. I. Richman, R. A. Pearl, C. Linge, and R. Grover, "Profiling cytochrome P450 CYP1 enzyme expression in primary melanoma and disseminated disease utilizing spectral imaging microscopy (SIM)," J. Clin. Oncol. (Meeting Abstracts) 25, 8556 (2007).
67.
V. Calleja, D. Alcor, M. Laguerre, J. Park, B. Vojnovic, B. A. Hemmings, J. Downward, P. J. Parker, and B. Larijani, "Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo," PloS Biology 5, 780–791 (2007).
68.
P. R. Barber, R. J. Locke, G. P. Pierce, K. Rothkamm, and B. Vojnovic, "Gamma-H2AX Foci Counting: Image processing and control software for high-content screening," Proc. SPIE 6441, 64411M (2007).
69.
M. N. Alvarez, G. Peluffo, L. Folkes, P. Wardman, and R. Radi, "Reaction of the carbonate radical with the spin-trap 5,5-dimethyl-1-pyrroline-N-oxide in chemical and cellular systems: Pulse radiolysis, electron paramagnetic resonance, and kinetic-competition studies," Free Radical Bio. Med. 43, 1523–1533 (2007).
70.
I. D. C. Tullis, S. M. Ameer-Beg, P. R. Barber, V. Rankov, and B. Vojnovic, "Mapping femtosecond pulse front distortion and group velocity dispersion in multiphoton microscopy," Proc. SPIE 6089, 60890Y (2006).
71.
C. C. Reyes-Aldasoro, S. A. Hill, I. Wilson, V. E. Prise, P. R. Barber, S. M. Ameer-Beg, B. Vojnovic, V. J. Cunningham, and G. M. Tozer, "Multiphoton fluorescence microscopy for assessing vascular permeability in experimental tumours; effects of CA-4-P, VEGF isoforms & ANG-1," in BACR/BMS Special Conference “‘Tumour Vasculature: New Targets & Therapies’” /Angiogenesis (Springer-Netherlands, 2006), Vol. 9, pp. 1–38.
72.
D. R. Matthews, H. D. Summers, K. Njoh, R. J. Errington, P. J. Smith, P. Barber, S. Ameer-Beg, and B. Vojnovic, "Technique for measurement of fluorescence lifetime by use of stroboscopic excitation and continuous-wave detection," Applied Optics 45, 2115–2123 (2006).
73.
L. A. G. Lucas, P. R. Barber, K. Jiang, B. Vojnovic, G. A. Soff, G. M. Tozer, and C. A. Mitchell, "Effect Of Angiostatin4.5 On Tumour Blood Vessels.," Angiogenesis 9, 38 (2006).
74.
K. J. Kirkby, G. W. Grime, R. P. Webb, N. F. Kirkby, M. Folkard, K. Prise, and B. Vojnovic, "A scanning focused vertical ion nanobeam: A new UK facility for cell irradiation and analysis," Radiation Research 166, 654–655 (2006).
75.
S. Ganesan, S. M. Ameer-beg, T. T. C. Ng, B. Vojnovic, and F. S. Wouters, "A dark yellow fluorescent protein (YFP)-based Resonance Energy-Accepting Chromoprotein (REACh) for Förster resonance energy transfer with GFP," Proceedings of the National Academy of Sciences of the United States of America 103, 4089 –4094 (2006).
76.
M. Folkard, K. M. Prise, C. Shao, S. Gilchrist, G. Schettino, A. G. Michette, and B. Vojnovic, "Understanding radiation damage to cells using microbeams," Acta Physica Polonica A 109, 257–264 (2006).
77.
M. Folkard, K. D. Atkinson, G. Flaccavento, P. R. Barber, R. J. Locke, G. Pierce, S. Gilchrist, A. G. Michette, K. M. Prise, and B. Vojnovic, "Development of the GCI multitarget X-ray microprobe," Extended Abstracts of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response published in Radiation Research 166, 659–660 (2006).
78.
G. Flaccavento, K. D. Atkinson, P. R. Barber, R. J. Locke, G. Pierce, S. Gilchrist, A. G. Michette, K. M. Prise, B. Vojnovic, and M. Folkard, "Performance of the GCI multitarget X-ray microprobe," Extended Abstracts of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response published in Radiation Research 166, 660–661 (2006).
79.
P. R. Barber, R. J. Locke, G. P. Pierce, R. G. Newman, M. Folkard, and B. Vojnovic, "The GCI Multitarget X-ray Microprobe: Imaging, Control and Software Automation," Extended Abstracts of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response published in Radiation Research 166, 663–4 (2006).
80.
S. Akerman, C. Kanthou, K. L. Pettyjohn, P. R. Barber, C. Coralli, G. U. Dachs, S. Harris, D. J. Honess, F. Hylands, C. R. Ireson, V. E. Prise, C. Ruhrberg, D. Shima, A. J. Steele, I. Wilson, S. A. Hill, and G. M. Tozer, "Tumour Cells Expressing Only Single Vegf Isoforms (120, 164 Or 188) Form Tumours With Very Different Vascular Maturities And Response To Combretastatin A-4-P.," Angiogenesis 9, 28–9 (2006).
81.
G. M. Tozer, S. M. Ameer-Beg, J. Baker, P. R. Barber, S. A. Hill, R. J. Hodgkiss, R. Locke, V. E. Prise, I. Wilson, and B. Vojnovic, "Intravital imaging of tumour vascular networks using multi-photon fluorescence microscopy," Advanced Drug Delivery Reviews 57, 135–152 (2005).
82.
V. Rankov, R. J. Locke, R. J. Edens, P. R. Barber, and B. Vojnovic, "An algorithm for image stitching and blending," Proc. SPIE 5701, 190–199 (2005).
83.
M. Peter, S. M. Ameer-Beg, M. K. Y. Hughes, M. D. Keppler, S. Prag, M. Marsh, B. Vojnovic, and T. Ng, "Multiphoton-FLIM Quantification of the EGFP-mRFP1 FRET Pair for Localization of Membrane Receptor-Kinase Interactions," Biophysical Journal 88, 1224–1237 (2005).
84.
M. Parsons, J. Monypenny, S. M. Ameer-Beg, T. H. Millard, L. M. Machesky, M. Peter, M. D. Keppler, G. Schiavo, R. Watson, J. Chernoff, D. Zicha, B. Vojnovic, and T. Ng, "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells," Molecular and Cellular Biology 25, 1680–1695 (2005).
85.
D. R. Matthews, H. D. Summers, K. Njoh, R. J. Errington, P. J. Smith, S. Ameer-Beg, and B. Vojnovic, "Time-resolved fluorescence measurements using self-pulsing 650-nm laser diodes," in Nanobiophotonics and Biomedical Applications II (SPIE, 2005), Vol. 5705, pp. 23–31.
86.
M. Folkard, K. Prise, G. Schettino, C. Shao, S. Gilchrist, and B. Vojnovic, "New insights into the cellular response to radiation using microbeams," Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms 231, 189–194 (2005).
87.
R. J. Errington, S. M. Ameer-beg, B. Vojnovic, L. H. Patterson, M. Zloh, and P. J. Smith, "Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells," Advanced Drug Delivery Reviews 57, 153–167 (2005).
88.
P. R. Barber, R. J. Edens, and B. Vojnovic, "Acquisition and analysis of spectral image data by linear un-mixing, cluster computing and a novel spectral imager," Proc. SPIE 5694, 53–61 (2005).
89.
P. R. Barber, S. M. Ameer-Beg, J. Gilbey, R. J. Edens, I. Ezike, and B. Vojnovic, "Global and pixel kinetic data analysis for FRET detection by multi-photon time-domain FLIM," Proc. SPIE 5700, 171–181 (2005).
90.
G. Atkin, P. R. Barber, B. Vojnovic, F. M. Daley, R. Glynne-Jones, and G. D. Wilson, "Correlation of spectral imaging and visual grading for the quantification of thymidylate synthase protein expression in rectal cancer," Human Pathology 36, 1302–1308 (2005).
91.
S. M. Ameer-Beg, M. Peter, M. D. Keppler, S. Prag, P. R. Barber, T. C. Ng, and B. Vojnovic, "Dynamic imaging of protein-protein interactions by MP-FLIM," Proc. SPIE 5700, 152–161 (2005).
92.
B. Vojnovic, R. J. Locke, S. M. Ameer-Beg, P. R. Barber, M. Folkard, K. Prise, and B. D. Michael, "Cell Imaging Techniques for use with Microbeams," Radiation Research 161, 104–105 (2004).
93.
G. Schettino, M. Folkard, K. M. Prise, L. Wu, K. D. Atkinson, B. Vojnovic, A. G. Michette, and B. D. Michael, "Improvement of the GCI X-ray microprobe and bystander studies using V79 cells," Radiation Research 161, 112–113 (2004).
94.
K. M. Prise, M. Folkard, B. Vojnovic, and B. D. Michael, "Targeting radiation at the subcellular, cellular and tissue levels: Future strategies," in Life Sciences and Radiation: Accomplishments and Future Directions (Springer-Verlag Berlin, 2004), Vol. IX, pp. 225–234.
95.
M. Parsons, B. Vojnovic, and S. Ameer-Beg, "Imaging protein-protein interactions in cell motility using fluorescence resonance energy transfer (FRET)," Biochemical Society Transactions 32, 431–433 (2004).
96.
G. Kashino, K. M. Prise, G. Schettino, M. Folkard, B. Vojnovic, B. D. Michael, K. Suzuki, S. Kodama, and M. Watanabe, "Evidence for induction of DNA double strand breaks in the bystander response to targeted soft X-rays in CHO cells," Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis 556, 209–215 (2004).
97.
M. Folkard, B. Vojnovic, K. M. Prise, K. Atkinson, G. Schettino, A. G. Michette, S. Gilchrist, R. Sunderland, and B. D. Michael, "The future of the GCI microbeams," Radiation Research 161, 88–89 (2004).
98.
D. M. Carnell, R. E. Smith, F. M. Daley, P. R. Barber, P. J. Hoskin, G. W. Wilson, G. I. Murray, and S. A. Everett, "Target validation of cytochrome p450 cyp1b1 in prostate carcinoma and protein expression in associated hyperplastic and pre-malignant tissue," International Journal of Radiation Oncology, Biology and Physics 58, 500–509 (2004).
99.
K. D. Atkinson, M. Folkard, B. Vojnovic, G. Schettino, K. M. Prise, B. D. Michael, and A. G. Michette, "Developing a laboratory-based titanium K-alpha X-ray microprobe," Radiation Research 161, 103–104 (2004).
100.
G. Schettino, M. Folkard, B. Vojnovic, K. M. Prise, K. D. Held, and B. D. Michael, "Low-dose studies of bystander cell killing with targeted soft X rays," Radiation Research 160, 505–511 (2003).
101.
G. Schettino, M. Folkard, A. G. Michette, B. Vojnovic, S. J. Pfauntsch, K. Prise, K. Atkinson, J. Holroyd, and B. D. Michael, "The Gray Cancer Institute X-ray microprobe and its radiobiological applications," J. Phys. IV France 104, 301–304 (2003).
102.
P. E. Morton, T. C. Ng, S. A. Roberts, B. Vojnovic, and S. M. Ameer-Beg, "Time resolved multiphoton imaging of the interaction between the PKC and NF kappa B signalling pathways," in Confocal, Multiphoton, and Nonlinear Microscopic Imaging, Proceedings of the Society of Photo-Optical Instrumentation Engineers (Spie) (Spie-Int Society Optical Engineering, 2003), Vol. 5139, pp. 216–222.
103.
C. G. Loukas, G. D. Wilson, B. Vojnovic, and A. Linney, "An image analysis-based approach for automated counting of cancer cell nuclei in tissue sections," Cytometry Part A 55A, 30–42 (2003).
104.
B. Kysela, A. J. Doherty, M. Chovanec, T. Stiff, S. M. Ameer-Beg, B. Vojnovic, P. M. Girard, and P. A. Jeggo, "Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule," Journal of Biological Chemistry 278, 22466–22474 (2003).
105.
M. L. Greer, F. M. Daley, P. Barber, G. I. Murray, L. H. Patterson, and S. A. Everett, "Cytochrome P450CYP1B1 versus GLUT 1 protein expression during the development of head and neck squamous cell carcinomas (HNSCCs)," Br. J. Cancer 88, S33–S33 (2003).
106.
M. Folkard, B. Vojnovic, S. Gilchrist, K. M. Prise, and B. D. Michael, "The design and application of ion microbeams for irradiating living cells and tissues," Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms 210, 302–307 (2003).
107.
D. M. Carnell, R. E. Smith, F. M. Daley, P. R. Barber, P. J. Hoskin, G. W. Wilson, G. I. Murray, and S. A. Everett, "Cytochrome p450 cyp1b1 protein expression in prostate carcinoma and associated hyperplastic and pre-malignant tissue.," The International Joumal of Radiation Oncology, Biology, and Physics (2003).
108.
V. Calleja, S. M. Ameer-Beg, B. Vojnovic, R. Woscholski, J. Downward, and B. Larijani, "Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy (vol 372, pg 33, 2003)," Biochemical Journal 373, 999–999 (2003).
109.
P. R. Barber, B. Vojnovic, S. M. Ameer-Beg, R. J. Hodgkiss, G. M. Tozer, and J. Wilson, "Semi-automated software for the three-dimensional delineation of complex vascular networks," Journal of Microscopy 211, 54–62 (2003).
110.
P. R. Barber, B. Vojnovic, G. Atkin, F. M. Daley, S. A. Everett, G. D. Wilson, and J. D. Gilbey, "Applications of cost-effective spectral imaging microscopy in cancer research," Journal of Physics D: Applied Physics 36, 1729 (2003).
111.
S. M. Ameer-Beg, N. Edme, M. Peter, P. R. Barber, T. Ng, and B. Vojnovic, "Imaging protein-protein interactions by multiphoton FLIM," Proc. SPIE 5139, 180–189 (2003).
112.
P. Wardman, M. J. Burkitt, K. B. Patel, A. Lawrence, C. M. Jones, S. A. Everett, and B. Vojnovic, "Pitfalls in the use of common luminescent probes for oxidative and nitrosative stress," Journal of Fluorescence 12, 65–68 (2002).
113.
L. J. van ’t Veer, H. Dai, M. J. van de Vijver, Y. D. He, A. A. M. Hart, M. Mao, H. L. Peterse, K. van der Kooy, M. J. Marton, A. T. Witteveen, G. J. Schreiber, R. M. Kerkhoven, C. Roberts, P. S. Linsley, R. Bernards, and S. H. Friend, "Gene expression profiling predicts clinical outcome of breast cancer," Nature 415, 530–536 (2002).
114.
G. M. Tozer, D. J. Honess, J. Wilson, S. A. Hill, R. J. Hodgkiss, S. Ameer-Beg, B. Vojnovic, and V. E. Prise, "Efficacy of the tumour vascular targeting agent combretastatin A-4-P at clinically relevant doses," in 22nd Meeting of the European Society for Microcirculation: Microcirculation and Vascular Biology (Monduzzi Editore, 2002), pp. 43–47.
115.
P. J. Smith, M. Wiltshire, G. Feeney, M. Shelley, M. J. Chappell, N. D. Evans, S. Ameer-Beg, B. Vojnovic, and R. J. Errington, "Mapping and modelling of anticancer drug-DNA interactions in live tumour cells using time-lapse two-photon imaging and a two-photon “dark” quenching probe," Cytometry 36–36 (2002).
116.
G. Schettino, M. Folkard, K. M. Prise, B. Vojnovic, and B. D. Michael, "Upgrading of the Gray Laboratory soft X-ray microprobe with aluminum K-shell X rays and measurement of the effect of a carbon K-shell X-ray beam of different size focused into V79 cell nuclei," Radiation Research 158, 374–375 (2002).
117.
S. A. Roberts, S. M. Ameer-Beg, B. Vojnovic, and P. Wardman, "Intracellular signaling in the NF Kappa B activation pathway following oxidative stress measured by fluorescence lifetime imaging of fluorescent proteins," British Journal of Cancer 86, S81 (Poster Presentation) (2002).
118.
K. M. Prise, O. V. Belyakov, M. Folkard, A. Ozols, G. Schettino, B. Vojnovic, and B. D. Michael, "Investigating the cellular effects of isolated radiation tracks using microbeam techniques," in Space Life Sciences: Biological Research and Space Radiation, Advances in Space Research (Pergamon-Elsevier Science Ltd, 2002), Vol. 30, pp. 871–876.
119.
R. J. Maxwell, J. Wilson, V. E. Prise, B. Vojnovic, G. J. Rustin, M. A. Lodge, and G. M. Tozer, "Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI," Nmr in Biomedicine 15, 89–98 (2002).
120.
M. Folkard, B. Vojnovic, K. M. Prise, and B. D. Michael, "The application of charged-particle microbeams in radiobiology," Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms 188, 49–54 (2002).
121.
M. Folkard, B. Vojnovic, S. Gilchrist, K. M. Prise, and B. D. Michael, "Development of the gray laboratory charged-particle microbeam," Radiation Research 158, 366–367 (2002).
122.
S. A. Everett, E. Swann, M. A. Naylor, M. R. L. Stratford, K. B. Patel, N. Tian, R. G. Newman, B. Vojnovic, C. J. Moody, and P. Wardman, "Modifying rates of reductive elimination of leaving groups from indolequinone prodrugs: a key factor in controlling hypoxia-selective drug release," Biochemical Pharmacology 63, 1629–1639 (2002).
123.
P. Wardman, M. J. Burkitt, A. Lawrence, K. B. Patel, M. R. L. Stratford, and B. Vojnovic, "Facts and artefacts in the use of fluorescent and luminescent probes for oxidative and nitrosative stress," Free Radical Biology and Medicine 31, S15–S15 (2001).
124.
G. M. Tozer, V. E. Prise, J. Wilson, M. Cemazar, S. Shan, M. W. Dewhirst, P. R. Barber, B. Vojnovic, and D. J. Chaplin, "Mechanisms Associated with Tumor Vascular Shut-Down Induced by Combretastatin A-4 Phosphate: Intravital Microscopy and Measurement of Vascular Permeability.," Cancer Research 61, 6413–6422 (2001).
125.
E. Swann, C. J. Moody, M. R. L. Stratford, K. B. Patel, M. A. Naylor, B. Vojnovic, P. Wardman, and S. A. Everett, "Rates of reductive elimination of substituted nitrophenols from the (indol-3-yl)methyl position of indolequinones," Journal of the Chemical Society-Perkin Transactions 2 1340–1345 (2001).
126.
B. M. Seddon, D. J. Honess, B. Vojnovic, G. M. Tozer, and P. Workman, "Measurement of tumor oxygenation: In vivo comparison of a luminescence fiber-optic sensor and a polarographic electrode in the P22 tumor," Radiation Research 155, 837–846 (2001).
127.
G. Schettino, M. Folkard, K. M. Prise, B. Vojnovic, A. G. Bowey, and B. D. Michael, "Low-dose hypersensitivity in Chinese hamster V79 cells targeted with counted protons using a charged-particle microbeam," Radiation Research 156, 526–534 (2001).
128.
B. D. Michael, K. D. Held, G. Schettino, M. Folkard, K. M. Prise, and B. Vojnovic, "Charged-particle and focused soft X-ray microbeams for investigating individual and collective radiation responses of cells," Radiation Research 156, 439–440 (2001).
129.
C. G. Loukas, G. D. Wilson, B. Vojnovic, and A. D. Linney, "Image-analysis-based assessment of hypoxia and vasculature in bladder tumors," in Medical Image Acquisition and Processing (Proc. SPIE - Medical Image Processing I, 2001), Vol. 4549, pp. 52–57.
130.
C. G. Loukas, G. D. Wilson, B. Vojnovic, and A. Linney, "Image analysis based assessment of hypoxia and vasculature in bladder tumours," in Medical Image Acquisition and Processing, Proceedings of the Society of Photo-Optical Instrumentation Engineers (Spie) (Spie-Int Society Optical Engineering, 2001), Vol. 4549, pp. 52–57.
131.
C. G. Loukas, G. D. Wilson, B. Vojnovic, and A. Linney, "An image analysis technique for simultaneous tumour hypoxia grading and blood vessel detection in tissue sections," in Metmbs’01: Proceedings of the International Conference on Mathematics and Engineering Techniques in Medicine and Biological Sciences (C S R E a Press, 2001), pp. 439–445.
132.
S. M. Galbraith, D. J. Chaplin, F. Lee, M. R. L. Stratford, R. J. Locke, B. Vojnovic, and G. M. Tozer, "Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo," Anticancer Research 21, 93–102 (2001).
133.
M. Folkard, G. Schettino, B. Vojnovic, A. G. Michette, C. David, S. J. Pfauntsch, K. M. Prise, and B. D. Michael, "Development and application of a focused ultrasoft X-ray probe for radiobiological applications," in X-Ray Micro- and Nano-Focusing: Applications and Techniques Ii, Proceedings of the Society of Photo-Optical Instrumentation Engineers (Spie) (Spie-Int Society Optical Engineering, 2001), Vol. 4499, pp. 10–18.
134.
M. Folkard, G. Schettino, B. Vojnovic, S. Gilchrist, A. G. Michette, S. J. Pfauntsch, K. M. Prise, and B. D. Michael, "A focused ultrasoft X-ray microbeam for targeting cells individually with submicrometer accuracy," Radiation Research 156, 796–804 (2001).
135.
M. Folkard, K. M. Prise, B. Vojnovic, S. Gilchrist, G. Schettino, O. V. Belyakov, A. Ozols, and B. D. Michael, "The impact of microbeams in radiation biology," Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms 181, 426–430 (2001).
136.
S. A. Everett, M. A. Naylor, M. R. L. Stratford, K. B. Patel, E. Ford, A. Mortensen, A. C. Ferguson, B. Vojnovic, and P. Wardman, "Iminoxyl radicals and stable products from the one-electron oxidation of 1-methylindole-3-carbaldehyde oximes," Journal of the Chemical Society-Perkin Transactions 2 2, 1989–1997 (2001).
137.
S. A. Everett, M. A. Naylor, P. Barraja, E. Swann, K. B. Patel, M. R. L. Stratford, A. R. Hudnott, B. Vojnovic, R. J. Locke, P. Wardman, and C. J. Moody, "Controlling the rates of reductively-activated elimination from the (indol-3-yl)methyl position of indolequinones," Journal of the Chemical Society-Perkin Transactions 2 843–860 (2001).
138.
P. R. Barber, B. Vojnovic, J. Kelly, C. R. Mayes, P. Boulton, M. Woodcock, and M. C. Joiner, "Automated Counting of Mammalian Cell Colonies.," Physics in Medicine and Biology 46, 63–76 (2001).
139.
G. Schettino, M. Folkard, B. Vojnovic, A. G. Michette, D. Stekel, S. J. Pfauntsch, K. M. Prise, and B. D. Michael, "The ultrasoft X-ray microbeam: A sub-cellular probe of radiation response," Radiation Research 153, 223 (2000).
140.
K. M. Prise, M. Folkard, B. D. Michael, B. Vojnovic, B. Brocklehurst, A. Hopkirk, and I. H. Munro, "Critical energies for SSB and DSB induction in plasmid DNA by low-energy photons: action spectra for strand-break induction in plasmid DNA irradiated in vacuum," International Journal of Radiation Biology 76, 881–890 (2000).
141.
K. H. Pigott, S. Dische, B. Vojnovic, and M. I. Saunders, "Sweat gland function as a measure of radiation change," Radiotherapy and Oncology 54, 79–85 (2000).
142.
C. G. Loukas, G. D. Wilson, and B. Vojnovic, "Automated segmentation of cancer cell nuclei in complex tissue sections," in Biomonitoring and Endoscopy Technologies (SPIE, 2000), Vol. 4158, pp. 188–198.
143.
M. Folkard, B. Vojnovic, K. J. Hollis, A. G. Bowey, S. J. Watts, I. Saarikivi, and E. Citations, "Proceedings of the 4th International Workshop: Microbeam Probes of Cellular Radiation Response 1 Killiney Bay, Dublin, Ireland, July 17-18, 1999," Radiation Research 153, 220–238 (2000).
144.
M. Folkard, K. M. Prise, B. Vojnovic, B. Brocklehurst, and B. D. Michael, "Critical energies for ssb and dsb induction in plasmid DNA by vacuum-UV photons: an arrangement for irradiating dry or hydrated DNA with monochromatic photons," International Journal of Radiation Biology 76, 763–771 (2000).
145.
M. Folkard, S. X. Peng, B. Vojnovic, S. Gilchrist, K. M. Prise, and B. D. Michael, "The performance of the Gray Laboratory charged-particle microbeam," Radiation Research 153, 220–221 (2000).
146.
P. R. Barber, B. Vojnovic, J. Kelly, C. R. Mayes, P. Boulton, M. Woodcock, and M. C. Joiner, "An automated colony counter utilising a compact Hough transform.," in Medical Image Understanding and Analysis, MIUA2000, S. Arridge and A. Todd-Pokropek, eds. (Communications in Print Plc, UCL, 2000), pp. 41–44.
147.
P. Wardman and B. Vojnovic, "Redox reactions of lucigenin," Free Radical Biology and Medicine 27, Supplement 1, S15 (1999).
148.
B. Vojnovic and R. G. Newman, "Quick-on, delayed-off switching," Electronics World 105, 828–828 (1999).
149.
G. M. Tozer, V. E. Prise, I. Wilson, B. Vojnovic, and D. J. Chaplin, "Therapeutic targeting of the tumour vasculature using the tubulin-binding agent combretastatin A4-P," Journal of Vascular Research 36, 328–329 (1999).
150.
S. M. Galbraith, F. Lee, B. Vojnovic, G. M. Tozer, and D. Chaplin, "Quantitative analysis of endothelial cell shape change after treatment with combretastatin A4 phosphate," Clinical Cancer Research 5, 3809S–3809S (1999).
151.
B. Vojnovic and R. G. Newman, "Wide-band, dc-isolated amplifier," Electronics World 104, 480–481 (1998).
152.
B. Vojnovic and R. G. Newman, "Rapid stop for dc motors," Electronics World 104, 483–483 (1998).
153.
S. A. Hill, D. R. Collingridge, B. Vojnovic, and D. J. Chaplin, "Tumor radiosensitization by high-oxygen-content gases: Influence of the carbon dioxide content of the inspired gas on PO2, microcirculatory function and radiosensitivity," International Journal of Radiation Oncology Biology Physics 40, 943–951 (1998).
154.
G. Schettino, M. Folkard, K. M. Prise, B. Vojnovic, T. English, A. G. Michette, S. J. Pfaunttsch, M. Forsberg, and B. D. Michael, "The soft X ray microprobe: A fine subcellular probe for investigating the spatial aspects of the interaction of ionising radiation with tissue. Microdosimetry: An Interdisciplinary Approach, D.T. Goodhead, P. O’Neill and H.G. Menzel, Proceedings of the 12th Symposium on Microdosimetry: An Interdisciplinary Meeting on Radiation Quality, Molecular Mechanisms, Cellular Effects and Health Consequences of Low Level Ionising Radiation (Oxford, UK).," in Microdosimetry: An Interdisciplinary Approach (1997), pp. 347–350.
155.
M. Folkard, B. Vojnovic, G. Schettino, M. Forsberg, G. Bowey, K. M. Prise, B. D. Michael, A. G. Michette, and S. J. Pfauntsch, "Two approaches for irradiating cells individually: a charged-particle microbeam and a soft X-ray microprobe," Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms 130, 270–274 (1997).
156.
M. Folkard, B. Vojnovic, K. M. Prise, A. G. Bowey, R. J. Locke, G. Schettino, and B. D. Michael, "A charged-particle microbeam .1. Development of an experimental system for targeting cells individually with counted particles," International Journal of Radiation Biology 72, 375–385 (1997).
157.
M. Folkard, K. M. Prise, B. Vojnovic, G. Bowey, C. Pullar, G. Schettino, and B. D. Michael, "Targetting cells individually using a charged particle microbeam: The biological effects of single or multiple traversals of protons and 3He2+ ions. Microdosimetry: An Interdisciplinary Approach, D.T. Goodhead, P. O’Neill and H.G. Menzel, Proceedings of the 12th Symposium on Microdosimetry: An Interdisciplinary Meeting on Radiation Quality, Molecular Mechanisms, Cellular Effects and Health Consequences of Low Level Ionising Radiation (Oxford, UK).," in Proceedings of the 12th Symposium on Microdosimetry (1997), pp. 323–326.
158.
D. R. Collingridge, W. K. Young, B. Vojnovic, P. Wardman, E. M. Lynch, S. A. Hill, and D. J. Chaplin, "Measurement of tumor oxygenation: A comparison between polarographic needle electrodes and a time-resolved luminescence-based optical sensor," Radiation Research 147, 329–334 (1997).
159.
W. K. Young, B. Vojnovic, and P. Wardman, "Measurement of oxygen tension in tumours by time-resolved fluorescence," British Journal of Cancer 74, S256–S259 (1996).
160.
W. K. Young, B. Vojnovic, and P. Wardman, "Fibre optic sensor for oxygen measurement in tumours," in Medical and Fiber Optic Sensors and Delivery Systems, Proceedings Of, Proceedings of the Society of Photo-Optical Instrumentation Engineers (Spie) (Spie - Int Soc Optical Engineering, 1996), Vol. 2631, pp. 56–63.
161.
A. Rojas, B. Vojnovic, H. Johns, M. C. Joiner, C. Martindale, J. F. Fowler, and J. Denekamp, "Radiosensitisation in normal tissues with oxygen, carbogen or nicotinamide: Therapeutic gain comparisons for fractionated x-ray schedules," Radiotherapy and Oncology 39, 53–64 (1996).
162.
M. Folkard, K. M. Prise, B. Vojnovic, H. C. Newman, M. J. Roper, and B. D. Michael, "Inactivation of V79 cells by low-energy protons, deuterons and helium-3 ions," International Journal Of Radaition Biology 69, 729–738 (1996).
163.
B. M. Rogina and B. Vojnovic, "Monitoring of Co-60 radiation source parameters by optoelectronic instrumentation," in Environmental Monitoring and Hazardous Waste Site Remediation, Proceedings of the Society of Photo-Optical Instrumentation Engineers (Spie) (Spie - Int Soc Optical Engineering, 1995), Vol. 2504, pp. 486–491.
164.
B. D. Michael, K. M. Prise, M. Folkard, B. Vojnovic, B. Brocklehurst, I. H. Munro, and A. Hopkirk, "Critical energies for SSB and DSB induction in plasmid DNA: Studies using synchrotron radiation," in Radiation Damage in DNA: Structure/Function Relationships at Early Times (Battelle Press, 1995), pp. 251–258.
165.
M. Folkard, K. M. Prise, B. Vojnovic, H. C. Newman, M. J. Roper, K. J. Hollis, and B. D. Michael, "Conventional and Microbeam Studies Using Low-Energy Charged-Particles Relevant to Risk Assessment and the Mechanisms of Radiation Action," Radiation Protection Dosimetry 61, 215–218 (1995).
166.
M. Folkard, K. M. Prise, B. Vojnovic, B. Brocklehurst, I. H. Munro, A. Hopkirk, and B. D. Michael, "DNA damage by low energy photons and electrons," in Radiation Research 1895-1995, Congress Proceedings (10th Icrr Society (Int Congress Radiation Res), 1995), pp. 204–207.
167.
B. Vojnovic and R. A. Orchard, "Switched-Gain Amplifier Minimizes Dc Shift," Electronics World & Wireless World 332–332 (1994).
168.
B. D. Michael, K. M. Prise, M. Folkard, B. Vojnovic, B. Brocklehurst, I. H. Munro, and A. Hopkirk, "Action Spectra for Single-Strand and Double-Strand Break Induction in Plasmid DNA - Studies Using Synchrotron-Radiation," International Journal of Radiation Biology 66, 569–572 (1994).
169.
B. D. Michael, K. M. Prise, M. Folkard, and B. Vojnovic, "An Investigation of Clustered Radiation-Induced Lesions in DNA," Radiation Protection Dosimetry 52, 277–281 (1994).
170.
M. Folkard, K. M. Prise, B. Vojnovic, S. Davies, M. J. Roper, and B. D. Michael, "Measurement of DNA-Damage by Electrons with Energies between 25 and 4000 Ev," International Journal of Radiation Biology 64, 651–658 (1993).
171.
R. K. Broszkiewicz, B. Vojnovic, and B. D. Michael, "Radiation-Induced Reduction of U(Vi) Ion at 6-Greater-Than-Ph-Greater-Than-4 as Observed by Fast Conductimetry," Radiation Physics and Chemistry 39, 137–140 (1992).
172.
R. K. Broszkiewicz and B. Vojnovic, "Redox Reactions in Aqueous-Solutions of Ptbr4(2-) and Ptbr6(2-)," Radiation Physics and Chemistry 40, 11–16 (1992).
173.
B. Vojnovic and K. J. Visscher, "Anomalous Observations in Dc-Polarized Transient Conductivity Measurements in Aqueous-Solutions Due to Electrode Surface Effects," Radiation Physics and Chemistry 38, 349–352 (1991).
174.
S. G. Martin, B. Vojnovic, and J. C. Murray, "Determination of X-Ray-Induced Damage to the Murine Colon Using Tissue Compliance Measurements," International Journal of Radiation Biology 59, 503–515 (1991).
175.
R. C. Fahey, B. Vojnovic, and B. D. Michael, "The Effects of Counterion Condensation and Co-Ion Depletion Upon the Rates of Chemical Repair of Poly(U) Radicals by Thiols," International Journal of Radiation Biology 59, 885–899 (1991).
176.
R. K. Broszkiewicz, B. Vojnovic, and B. D. Michael, "Reduction of the U(Vi) Ion - a Fast Conductimetry Study," Radiation Physics and Chemistry 37, 443–447 (1991).
177.
R. F. Anderson, K. B. Patel, and B. Vojnovic, "Absorption-Spectra of Radical Forms of 2,4-Dihydroxybenzoic Acid, a Substrate for P-Hydroxybenzoate Hydroxylase," Journal of Biological Chemistry 266, 13086–13090 (1991).
178.
B. Vojnovic, "Analogue Decision Circuit," Electronic Product Design 11, 17 (1990).
179.
B. Vojnovic, "BCD - Binary Converter," Electronic Product Design 19 (1989).
180.
S. G. Martin, J. C. Murray, and B. Vojnovic, "Changes in Colonic Compliance after X-Irradiation," International Journal of Radiation Biology 55, 893–893 (1989).
181.
R. J. Hodgkiss, B. Vojnovic, M. Woodcock, and B. D. Michael, "A Single-Shot Rapid-Mixing Device for Radiobiological Studies with Mammalian-Cells," International Journal of Radiation Biology 55, 705–715 (1989).
182.
M. Folkard, K. M. Prise, B. Vojnovic, S. Davies, M. J. Roper, and B. D. Michael, "The Irradiation of V79 Mammalian-Cells by Protons with Energies Below 2 Mev .1. Experimental Arrangement and Measurements of Cell-Survival," International Journal of Radiation Biology 56, 221–237 (1989).
183.
S. G. Martin, J. C. Murray, B. Vojnovic, and R. A. Orchard, "A New Method for the Investigation of Radiation-Induced Colorectal Damage in the Mouse," British Journal of Radiology 61, 879–880 (1988).
184.
B. Vojnovic, D. S. Sehmi, and R. G. Newman, "A Simple Radiation Beam Position Monitor," Physics in Medicine and Biology 32, 1179–1185 (1987).
185.
B. Vojnovic and B. D. Michael, "Reduction of electromagnetic interference from pulsed radiation sources," International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 30, 225–227 (1987).
186.
B. Vojnovic, "Synchronisaion of transient digitisers to random events," Rev. Sci. Instrum. 58, 878–880 (1987).
187.
B. Vojnovic, "Sensitive Long Pulse Beam Charge Monitor for Use with Charged-Particle Accelerators," Radiation Physics and Chemistry 29, 409–413 (1987).
188.
B. Vojnovic, "Extension of LF Response of Pulse Transformers," Electronic Product Design 8, 22 (1987).
189.
B. Vojnovic, "200 MHz clock synchronisation circuit," Electronic Product Design 8, 22 (1987).
190.
K. J. Visscher, M. P. de Haas, H. Loman, B. Vojnovic, and J. M. Warman, "Fast Protonation of Adenosine and of Its Radical Anion Formed by Hydrated Electron Attack; A Nanosecond Optical and Dc-conductivity Pulse Radiolysis Study," International Journal of Radiation Biology, Vol. 52,, 745–753 (1987).
191.
R. M. J. Palmer, A. G. Ferrige, and S. Moncada, "Nitric Oxide Release Accounts for the Biological Activity of Endothelium-derived Relaxing Factor," Nature 327, 524–526 (1987).
192.
M. Folkard, B. Vojnovic, K. M. Prise, and B. D. Michael, "An Arrangement for Irradiating Cultured-Mammalian-Cells with Aluminum Characteristic Ultrasoft X-Rays," Physics in Medicine and Biology 32, 1615–1626 (1987).
193.
B. Vojnovic, R. F. Anderson, and B. D. Michael, "A Pulse-Radiolysis Dc Conductivity Detection Technique with Nanosecond Time Resolution," Radiation Physics and Chemistry 27, 363–373 (1986).
194.
M. J. Gardner and D. G. Altman, "Confidence intervals rather than P values: estimation rather than hypothesis testing.," Br Med J (Clin Res Ed) 292, 746–750 (1986).
195.
R. F. Anderson, B. Vojnovic, K. B. Patel, and B. D. Michael, "Reaction of Alcohol Radicals with Cyclic Disulfides - an Optical and Conductimetric Pulse-Radiolysis Study," Radiation Physics and Chemistry 28, 219–222 (1986).
196.
B. Vojnovic and M. C. Joiner, "A multiple RF heating system for experimental hyperthermia in small animals," International Journal of Hyperthermia 1, 287–298 (1985).
197.
B. Vojnovic, "High Speed Mosfet Driver," Electronic Product Design 6, (1985).
198.
E. P. Dunphy, S. Dische, R. A. Orchard, B. Vojnovic, and M. Joiner, "Hyperthermia and the Radiation Reaction of Normal Skin," Strahlentherapie 161, 531–531 (1985).
199.
R. F. Anderson, B. Vojnovic, and B. D. Michael, "The Radiation-Chemical Yields of H3o+ and Oh- as Determined by Nanosecond Conductimetric Measurements," Radiation Physics and Chemistry 26, 301–303 (1985).
200.
B. Vojnovic, "A sensitive single-pulse beam charge monitor for use with charged particle accelerators," Radiation Physics and Chemistry (1977) 24, 517–522 (1984).
201.
B. Vojnovic, "A New Lease of Life for the Farmer-Baldwin Dosemeter," Phys. Med. Biol. 29, 301–303 (1984).
202.
M. P. de Haas, J. M. Warman, and B. Vojnovic, "Geminate Ions in Nanosecond Pulse Irradiated Ccl4 Detected by Dc Conductivity," Radiation Physics and Chemistry 23, 61–65 (1984).
203.
M. C. Joiner, J. Bremner, and B. Vojnovic, "Assessment of Thermocouple Probes for Use in Rf Fields," Strahlentherapie 158, 384–384 (1982).
204.
E. L. Travis, J. D. Down, L. Hall, B. Vojnovic, and S. J. Holmes, "Factors Affecting the Breathing Rate of Mice as Used for Studies of Radiation-Damage to Lungs," British Journal of Radiology 54, 50–53 (1981).
205.
M. C. Joiner, B. Vojnovic, and R. Davies, "Radiofrequency Diathermy for Heating Mouse-Tumors," British Journal of Radiology 54, 1119–1119 (1981).
206.
E. L. Travis, B. Vojnovic, E. E. Davies, and D. G. Hirst, "Plethysmographic Method for Measuring Function in Locally Irradiated Mouse Lung," British Journal of Radiology 52, 67–74 (1979).
207.
D. G. Hirst, B. Vojnovic, and B. Hobson, "Changes in Nerve-Conduction Velocity in the Mouse after Acute and Chronic Administration of Nitroimidazoles," British Journal of Cancer 39, 159–167 (1979).