Oxford University Gene Medicine : Gene Therapy for Lung Diseases


Welcome to the website of the Oxford University Gene Medicine Research Group. We are a University of Oxford research group based in the Radcliffe Department of Medicine at the John Radcliffe Hospital.

We are focused on the development of clinical gene therapies for the treatment of lung diseases. Our primary focus has been Cystic Fibrosis (CF) lung disease.

Together with colleagues at the University of Edinburgh and Imperial College London we form the UK Cystic Fibrosis Gene Therapy Consortium, funded by the Medical Research Council, the National Institute for Health Research and the UK Cystic Fibrosis Trust.

The Consortium is currently undertaking one of the world's largest ever gene therapy clinical trials in CF patients based on our gene therapy research.

Patient Recruitment for the Muti-Dose Clinical Trial

 

justgenetherapy.org

Just Gene Therapy Charity Launches to Support CF Gene Therapy.

We are pleased to announce the launch of new charity Just Gene Therapy with the specific aim of raising funds for gene therapy research for CF. The charity has been established by Rosie Barnes in conjunction with Professor Eric Alton, and is the only way in which donations can directly support the work of the Consortium.

Learn about Cystic Fibrosis

Research Highlights

Recent Publications from our Group

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UK CFGTC

How the Consortium works/FAQs

Consortium Website

Centre for Molecular Medicine, Edinburgh
The Roslin Institute
Dep of Gene Therapy, Imperial

Milestones

GL67A/pGM169

The Run-in Study

Single Dose Clinical Trial

Multi Dose Clinical Trial

 

Our Research

Non-viral Vector Development

Aerosol Mediated Gene Delivery

Viral Vector Development

Taqman Core Facility

Cystic Fibrosis

History of CF

Discovery of the CFTR Gene

CFTR Protein Structure

CFTR Function

CF Links

 

Gene Therapy

Introduction to Gene Therapy

Other CF Gene Therapy Groups

Why use Gene Therapy for CF

Target Cells for CF Gene Therapy

Barriers for CF Gene Therapy

Clinical Trials

Gene Therapy Successes

Gene Therapy Links

 

 

Publications

Papers in Journals

Conference Posters & Presentations

Book Chapters

D.Phil Theses

Lectures

 

Gene Therapy Seminars

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Directions & Venue