Publications

J Zong, K E Christensen, J Robertson,
Org. Lett. 2024, 26, 1556
Routes to Advanced Intermediates in the Synthesis of Tetracarbocyclic Sesquiterpenoids Daphnenoid A and Artatrovirenols A and B

W J M Lewis, E J Rayment, J Robertson,
Arkivoc 2024, (2), 202312079
Generation and Reversible Cyclisation of Furfurylic Radicals

L A Harwood, Z Xiong, K E Christensen, R Wang, L L Wong, J Robertson,
J. Am. Chem. Soc. 2023, 145, 27767
Selective P450BM3 Hydroxylation of Cyclobutylamine and Bicyclo[1.1.1]pentylamine Derivatives: Underpinning Synthetic Chemistry for Drug Discovery

S Li, J A O'Hanlon, A Mattimoe, H D Pickford, L A Harwood, L L Wong, J Robertson,
Org. Lett. 2023, 25, 7507
Two Total Syntheses of Trigoxyphins K and L

J Robertson, L R M Schrecker,
ChemRxiv 2023 (DOI:10.26434/chemrxiv-2023-rxtk7)
3,3-Bis[1-(trifluoromethylsulfonyl)-1,4-dihydropyridin-4-yl]benzofuran-2(3H)-one

J Zong, J Robertson,
Molecules 2023, 28, 3900
An Enantiospecific Synthesis of 5-epi-α-Bulnesene

A Vogiatzi, K Keklikoglou, K Makris, D S Argyrou, A
Zacharopoulos, V Sotiropoulou, N Parthenios, A Gkikas, M Kokkori, M S W Richardson, A L Fenwick, S Archontidi, C Arvanitidis, J Robertson, J Parthenios, G Zacharakis, S R F Twigg, A O M Wilkie, G Mavrothalassitis, Int. J. Mol. Sci. 2023, 24, 7961
Development of Erf-mediated Craniosynostosis and Pharmacological Amelioration

Y Zhang, Z Xiong, Y Li, M Wilson, K E Christensen, E Jacques, P Hernández-Lladó, J Robertson, L L Wong,
Nat. Synth. 2022, 1, 936
Enantioselective Oxidation of Unactivated C–H Bonds in Cyclic Amines by Iterative Docking-Guided Mutagenesis of P450BM3 (CYP102A1)
See the associated Research Briefing:
Accelerated Enzyme Evolution for Targeted C–H Oxidation in Cyclic Amines on page 921 of the December issue

D J Dearlove, D Holdsworth, T Kirk, L Hodson, E Charidemou, E Kvalheim, B Stubbs, A Beevers, J L Griffin, R Evans, J Robertson, K Clarke, P J Cox,
Front. Med. 2021, 8, 721673
beta-Hydroxybutyrate Oxidation in Exercise is Impaired by Low-Carbohydrate and High-Fat Availability

A W Sobanska, J Robertson, E Brzezinska,
Pharmaceuticals 2021, 14, 600
RP-18 TLC Chromatographic and Computational Study of Skin Permeability of Steroids

V A Palchykov, P C Dale, J Robertson,
New J. Chem. 2021, 45, 9020
Nucleophilic Vinylic Substitution in Bicyclic Methyleneaziridines: SNVpi or SNVsigma?

A W Sobanska, J Robertson, E Brzezinska,
Pharmaceuticals 2021, 14, 147
Application of RP-18 TLC Retention Data to Prediction of Transdermal Absorption of Drugs

W J M Lewis, D M Shaw, J Robertson,
Beilstein J. Org. Chem. 2021, 17, 334
Synthesis of Legonmycins A and B, C(7a)-Hydroxylated Bacterial Pyrrolizidines

L A Harwood, L L Wong, J Robertson,
Angew. Chem. Int. Ed. 2021, 60, 4434
Enzymatic Kinetic Resolution by Addition of Oxygen

K Y Seah, J Robertson,
Tetrahedron Lett. 2020, 61, 152170
Enantioselective Synthesis of C(9) Hydroxy Analogues of Hederacines A and B

Acknowledged structural correction in:
Tetrahedron Lett. 2020, 61, 151497
Corrigendum to "A 6/5/5/7 Heterotetracyclic Indole Derivative Alkaloid Isolated from Typhonium Giganteum"

J Zhou, J-H Feng, J Robertson, L Fang,
Bioorg. Med. Chem. Lett. 2020, 30, 127294
Corrigendum to "A Novel Monoterpenoid Indole Alkaloid with Anticancer Activity from Melodinus Khasianus"

K Y Seah, J Robertson,
Tetrahedron 2019, 75, 130661
Investigation of an Annulation-Fragmentation-Spirocyclisation Approach to Fawcettimine-type Lycopodium Alkaloids

J T R Liddon, P J Lindsay-Scott, J Robertson,
J. Org. Chem. 2019, 84, 13790
Secondary Products from Intramolecular Cycloadditions of Azidoalkyl Enol Ethers and Azidoalkyl Vinyl Bromides. 1-Azadienes, their Reactions with Diphenylketene, and Radical Cyclizations to form Bi- and Tricyclic Lactams

L-D Syntrivanis, L L Wong, J Robertson,
Eur. J. Org. Chem. 2018, 6369
Hydroxylation of Eleuthoside Synthetic Intermediates by P450BM3 (CYP102A1)

L-D Syntrivanis, F J. del Campo, J Robertson,
J. Flow Chem. 2018, 8, 123
An Electrochemical Flow Cell for the Convenient Oxidation of Furfuryl Alcohols

J O'Hanlon, X Ren, M Morris, L L Wong, J Robertson,
Org. Biomol. Chem. 2017, 15, 8780
Hydroxylation of Anilides by Engineered Cytochrome P450BM3

L-D Syntrivanis, J Robertson, Eur. J. Org. Chem. 2017, 4916
Synthesis of (E)-4-Methylhexa-3,5-dienol and its Diels–Alder Reaction with Thioester Dienophiles: a Short Enantioselective Synthesis of Bicyclic Lactones

O Zhurakovskyi, S R Ellis, A L Thompson, J Robertson,
Org. Lett. 2017, 19, 2174
Access to a Guanacastepene and Cortistatin-Related Skeleton via Ethynyl Lactone Ireland–Claisen Rearrangement and Transannular (4+3)-Cycloaddition of an Azatrimethylenemethane Diyl

J Robertson, K Stevens,
Nat. Prod. Rep. 2017, 34, 62
Pyrrolizidine Alkaloids: Occurrence, Biology, and Chemical Synthesis

B Martin, J Sedelmeier, A Bouisseau, P Fernandez-Rodriguez, J Haber, F Kleinbeck, S Kamptmann, F Susanne, P Hoehn, M Lanz, L Pellegatti, F Venturoni, J Robertson, M C Willis, B Schenkel,
Green Chem. 2017, 19, 1439
Toolbox Study for Application of Hydrogen Peroxide as a Versatile, Safe and Industrially-relevant Green Oxidant in Continuous Flow Mode

X Ren, J A O'Hanlon, M Morris, J Robertson, L L Wong,
ACS Catal. 2016, 6, 6833
Imidazolidin-4-ones via a Cytochrome P450-Catalyzed Intramolecular C-H Amination

A J Murray,N S Knight, M A Cole, L E Cochlin, E Carter, K Tchabanenko, T Pichulik, M K Gulston, H J Atherton, M A Schroeder, R M J Deacon, Y Kashiwaya, M T King, R Pawlosky, J N P Rawlins, D J Tyler, J L Griffin, J Robertson, R L Veech, K Clarke,
FASEB J. 2016, 30, 4021
Novel Ketone Diet Enhances Physical and Cognitive Performance

M Liebeke, N Strittmatter, S Fearn, A J Morgan, P Kille, J Fuchser, D Wallis, V Palchykov, J Robertson, E Lahive, D J Spurgeon, D McPhail, Z Takats, J G Bundy,
Nat. Commun. 2015, 6:7869
Unique Metabolites Protect Earthworms Against Plant Polyphenols

V A Pal'chikov, J Robertson,
Russ. J. Org. Chem. 2014, 50, 1369 [Zh. Org. Khim. 2014, 50, 1384]
Efficient Procedure for the Preparation of 2-Bromo-5-ethylfuran and its Unexpected Isomerization

W P Unsworth, N Clark, T O Ronson, K Stevens, A L Thompson, S G Lamont, J Robertson,
Chem. Commun. 2014, 50, 11393
Rhodium(II)-Catalysed Tandem Aziridination and Ring-opening: Stereoselective Synthesis of Functionalised Tetrahydrofurans

J Robertson, K Stevens,
Nat. Prod. Rep. 2014, 31, 1721
Pyrrolizidine Alkaloids

W P Unsworth, S G Lamont, J Robertson,
Tetrahedron 2014, 70, 7388
Substrate Scope and Stereocontrol in the Rh(II)-Catalysed Oxyamination of Allylic Carbamates

K Y Seah, S J Macnaughton, J W P Dallimore, J Robertson,
Org. Lett. 2014, 16, 884
Synthesis of Pandamarilactone-1

B Wu, G C Feast, A L Thompson, J Robertson,
J. Org. Chem. 2012, 77, 10623
Synthesis of Stereoisomers of Artemisia and Chrysanthemum Bis(acetylenic) Enol Ether Spiroacetals

K Clarke, K Tchabanenko, R Pawlowsky, E Carter, M T King, K Musa-Veloso, M Ho, A Roberts, J Robertson, T B VanItallie, R L Veech,
Regul. Toxicol. Pharmacol. 2012, 63, 401
Kinetics, Safety and Tolerability of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate in Healthy Adult Subjects

K Clarke, K Tchabanenko, R Pawlowsky, E Carter, N S Knight, A J Murray, L E Cochlin, M T King, A W Wong, A Roberts, J Robertson, R L Veech, Regul. Toxicol. Pharmacol. 2012, 63, 196
Oral 28-Day and Developmental Toxicity Studies of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate

S Naud, S J Macnaughton, B S Dyson, D J Woollaston, J W P Dallimore, J Robertson,
Org. Biomol. Chem. 2012, 10, 3506
Conformational Preferences of Oxy‐ Substituents in Butenolide‐tetrahydropyran Spiroacetals and Butenolide‐piperidine Spiro‐N,O‐acetals

K Stevens, A J Tyrrell, S Skerratt, J Robertson,
Org. Lett. 2011, 13, 5964
Synthesis of NP25302

W P Unsworth, K Stevens, S G Lamont, J Robertson,
Chem. Commun. 2011, 47, 7659
Stereospecificity in the Au-Catalysed Cyclisation of Monoallylic Diols. Synthesis of (+)-Iso-altholactone

J Robertson, C North, J E R Sadig,
Tetrahedron 2011, 67, 5011
Asymmetric Synthesis of the C(6–18) Bis(tetrahydropyran)spiroacetal Fragment of the Lituarines

J Robertson, K Clarke, R L Veech, WO
2010/120300 also US 9034613 B2 (2015)
Process for the Preparation of (3R)-Hydroxybutyl (3R)-hydroxybutyrate by Enzymatic Enantioselective Reduction Employing Lactobacillus brevis Alcohol Dehydrogenase

J W Levell, J P Gunning, P L Burn, J Robertson, I D W Samuel,
Org. Electron. 2010, 11, 1561
A Phosphorescent Poly(dendrimer) with Increased Viscosity for Solution-Processed OLED Devices

B Wu, A Mallinger, J Robertson,
Org. Lett. 2010, 12, 2818
Synthesis of Taurospongin A

J Robertson, G C Feast, L V White, V A Steadman, T D W Claridge,
Org. Biomol. Chem. 2010, 8, 3060
Structure and Reactivity of Bicyclic Methylene Aziridines Prepared by Intramolecular Aziridination of Allenes

J P Gunning, J W Levell, M F Wyatt, P L Burn, J Robertson, I D W Samuel,
Polymer Chem. 2010, 1, 730
The Development of Poly(dendrimers) for Advanced Processing

G C Feast, L W Page, J Robertson,
Chem. Commun. 2010, 46, 2835
The Intramolecular Amination of Allenes

J Robertson, W P Unsworth, S G Lamont,
Tetrahedron 2010, 66, 2363
Aspects of Stereocontrol in the L-Selectride Reduction of 4-Acyl-1,3-dioxolane Derivatives

J Robertson, P T Chovatia, T G Fowler, J M Withey, D J Woollaston,
Org. Biomol. Chem. 2010, 8, 226
Oxidative Spirocyclisation Routes Towards the Sawaranospirolides. Synthesis of ent-Sawaranospirolides C and D

G C Feast, J Haestier, L W Page, J Robertson, A L Thompson, D J Watkin,
Acta. Cryst. 2009, C65, o635
An Unusual Methylene Aziridine Refined in P21/c and the Nonstandard Setting P21/n

J Robertson, A J Tyrrell, P T Chovatia, S Skerratt,
Tetrahedron Lett. 2009, 50, 7141
Synthesis of Pyrrolidin-3-ones from Dihydropyran Precursors via Spiro-N,O-acetals

J Robertson, E Abdulmalek,
Tetrahedron Lett. 2009, 50, 3516
Concerning Directed Oxidation and Transacylation During a General Approach to Hydroxylated Lactams

J Robertson, M J Hall, S P Green,
Tetrahedron 2009, 65, 5541
Stereospecific α-Methallylation of Hydroxy-aldehydes by Silatropic Ene Cyclisation

J Robertson, S Naud,
Org. Lett. 2008, 10, 5445
Synthesis of Spiroacetal Enol Ethers by Oxidative Activation of Furan Derivatives

J Robertson, M J Palframan, S A Shea, K Tchabanenko, W P Unsworth, C Winters,
Tetrahedron 2008, 64, 11896
Radical 1,4-Aryl Transfer in Arylcarboxamides Leading to Phthalimides, Biaryls, and Enantiomerically Enriched β-Arylethylamines

A J Tyrrell, G C Feast, J Robertson,
Acta. Cryst. 2008, E64, o1261
(1RS, 4SR)-1,4-Dimethyl-3-dichloromethylene-2-oxabicyclo[2.2.2]oct-5-ene

J Robertson, K Stevens, S Naud,
Synlett 2008, 2083
Synthesis of Pyrenolide D Analogues

J Robertson, S P Green, M J Hall, A J Tyrrell, W P Unsworth,
Org. Biomol. Chem. 2008, 6, 2628
Further Studies on Silatropic Carbonyl Ene Cyclisations: β-Crotyl(diphenyl)silyloxy Aldehyde Substrates; Synthesis of 2-Deoxy-2-C-phenylhexoses

J Robertson, T G Fowler,
Org. Biomol. Chem. 2006, 4, 4307
Synthesis and Claisen Rearrangement of Bridged Bicyclic Enol Ethers of Relevance to the Course of Ketene s-cis-Diene Cycloaddition

M J Palframan, K Tchabanenko, J Robertson,
Tetrahedron Lett. 2006, 47, 8423
Aryl Pyrrolidinones via Radical 1,4-Aryl Migration and 5-endo-trig Cyclisation of N-(2-bromoallyl)arylcarboxamides

J Robertson, A J Tyrrell, S Skerratt,
Tetrahedron Lett. 2006, 47, 6285
Oxidation Products of 2-Acyl-4,5-dihydrofurans

J Robertson, S J Bell, A Krivokapic,
Org. Biomol. Chem. 2005, 3, 4246
On the Reaction of Diphenylketene with Isocyanides

J Robertson, J W P Dallimore,
Org. Lett. 2005, 7, 5007
Progress in the Synthesis of the Lituarines: Stereocontrol in Sequential C–C Bond Formation on a Spirobutenolide Template

J Robertson, P M Stafford, S J Bell,
J. Org. Chem. 2005, 70, 7133
Silatropic Carbonyl Ene Cyclisations in the Synthesis of Pseudosugars and Hydroxylated Piperidines

J Robertson, B M Doyle, C Hoarau, P Meo,
Org. Lett. 2004, 6, 3861
Stereoselective Synthesis of the Lituarine Tricyclic Spiroacetal

J Robertson, J W P Dallimore, P Meo,
Org. Lett. 2004, 6, 3857
Syntheses of the C(1–6) and C(19–24) Fragments of Lituarines A, B, and C

J Robertson, M Menard, R Ford,
Synlett 2004, 2788
An Approach to the Tricyclic Lactone Core of Brasoside and Related Natural Products

J Robertson, M Menard, R Ford,
Org. Biomol. Chem. 2004, 2, 2988
Conjugate Addition of Organocopper Reagents to γ-Alkoxybutenolides and Application to the Synthesis of Non-racemic Alkyl Cyclopentenones

J Robertson, M J Hall, P M Stafford, S P Green,
Org. Biomol. Chem. 2003, 1, 3758
Ene Cyclisations of α-(Prenyl)dialkylsilyloxy Aldehydes: Formation and Oxidative Cleavage of Oxasilacyclohexanols

J Robertson, M J Hall, S P Green,
Org. Biomol. Chem. 2003, 1, 3635
Stereospecificity in the Silicon Tethered α-(Methyl)allylation of Aldehydes

J Robertson and P M Stafford, In
Carbohydrates, Academic Press, Place, 2003, H M I Osborn (ed), Chapter 1, Selective Hydroxyl Protection and Deprotection [book]

J Robertson, Times Higher Education Supplement, January 4th 2002
Watch Out for Bearded Geezer [book review]

J Robertson, J Pillai, R K Lush,
Chem. Soc. Rev. 2001, 30, 94
Radical Translocation Reactions in Synthesis

J Robertson, H-W Lam, S Abazi, S L Roseblade, R K Lush,
Tetrahedron 2000, 56, 8959
Radical Cascade Processes Leading to Fused- and Spiro-bicyclic Ring Systems

J Robertson, R J D Hatley, D J Watkin,
J. Chem. Soc., Perkin Trans. 1 2000, 3389
Preparation of the Tricyclic Ketopyrrole Core of Roseophilin by Radical Macrocyclisation and Paal–Knorr Condensation

J Robertson, G O’Connor, C L Ringrose, D S Middleton,
Tetrahedron 200056, 8321
Silicon Tethered Alkenyl Transfer and Type I Ene Cyclisations

J Robertson, G O’Connor, T Sardharwala, D S Middleton,
Tetrahedron 2000, 56, 8309
Stereoselective Synthesis of Silacyclohexanols by Silicon Tethered Type II Ene Cyclisation

J Robertson, N Kuhnert, Y Zhao,
Heterocycles 2000, 53, 2415
Synthesis of 3-Chloro-2-formylpyrrole Derivatives

J Robertson,
Protecting Group Chemistry, Oxford University Press, Oxford, 2000 [book]

J Robertson, In
The Chemical Synthesis of Natural Products, Sheffield Academic Press, Sheffield, 2000, K J Hale (ed.), Chapter 4, Important Developments in the Total Synthesis of Alkaloids [book]

J Robertson, R J D Hatley,
J. Chem. Soc., Chem. Commun. 1999, 1455
Formal Synthesis of Roseophilin

N Kuhnert, J Peverley, J Robertson,
Tetrahedron Lett. 1998, 39, 3215
Bistrifluoromethanesulfonimide in the Catalytic Conjugate Allylation of α,β-Unsaturated Carbonyl Compounds

J Robertson, D S Middleton, G O’Connor, T Sardharwala,
Tetrahedron Lett. 1998, 39, 669
Oxasilacyclopentanes as Intermediates for Silicon Tethered Ene Cyclisations

J Robertson, J N Burrows,
Synthesis 1998, 63
Preparation and Reactivity of 2-Cyclodecynone

J Robertson, J N Burrows, P A Stupple,
Tetrahedron 1997, 53, 14807
Bicyclo[10.2.1]pentadecenone Derivatives by Free Radical Macrocyclisation

J Robertson, M A Peplow, J Pillai,
Tetrahedron Lett. 1996, 37, 5825
The Synthesis of (±)-Heliotridane and (6S,7S)-Dihydroxyheliotridane via Sequential Hydrogen Atom Abstraction and Cyclisation

J Robertson, G O’Connor, D S Middleton,
Tetrahedron Lett. 1996, 37, 3411
Silicon Tethered Type II Ene Cyclisations

J Robertson, J N Burrows,
Tetrahedron Lett. 1994, 35, 3777
Free Radical Rearrangement of Alkenyl Epoxy Silanes. Isolation of α-Trimethylsilyl Aldehydes

T Doi, J Robertson, G Stork, A Yamashita,
Tetrahedron Lett. 1994, 35, 1481
Regiospecificity in the Cyclization of 6-(1-Hydroxyalkyl) Geraniol Derivatives. A Simple Route to the Taxol A-ring System

J E Baldwin, R M Adlington, J Robertson,
Tetrahedron 1991, 47, 6795
Carbocyclic Ring Expansion Reactions via Radical Chain Processes. Part II

J E Baldwin, R M Adlington, M B Mitchell, J Robertson,
Tetrahedron 1991, 47, 5901
Intramolecular SH2’ Macrocyclisations

J E Baldwin, R M Adlington, M B Mitchell, J Robertson,
J. Chem. Soc., Chem. Commun. 1990, 1574
Radical Reactions in Organic Synthesis: Intramolecular SH2’ Macrocyclisations

J E Baldwin, R M Adlington, J Robertson,
Tetrahedron 1989, 45, 909
Carbocyclic Ring Expansion Reactions via Radical Chain Processes

J E Baldwin, R M Adlington, J Robertson,
J. Chem. Soc., Chem. Commun. 1988, 1404
Carbocyclic Ring Expansion Reactions via Radical Chain Processes

L M Harwood, J Robertson,
Tetrahedron Lett. 1987, 28, 5175
Preparation of Cyclic Ethers via Oxidative Cyclisation of 2-(4-Hydroxyalkyl)- and (5-Hydroxyalkyl)furans with DDQ


Published abstracts

LD Syntrivanis, F J del Campo, L L Wong, J Robertson, Abstr. Pap. Am. Chem. Soc. 2016, 251, 213
Studies Toward a Streamlined Total Synthesis of Eleutherobin and Analogues

O Zhurakovskyi, J Robertson,
Abstr. Pap. Am. Chem. Soc. 2012, 243, 578-ORGN
Pericyclic Rearrangements of Tethered Allene Azides

K Stevens, J Robertson,
Abstr. Pap. Am. Chem. Soc. 2011, 241, 255-ORGN
Total Synthesis of the Pyrrolizidine Alkaloid Natural Product NP25302

S Macnaughton, J Robertson, J Dallimore,
Abstr. Pap. Am. Chem. Soc. 2010, 239, 1066-ORGN
Development of an Extended Aza-Achmatowicz Cyclisation: Progress Towards the Total Synthesis of Pandamarilactone-1

G C Feast, J Robertson, L W Page,
Abstr. Pap. Am. Chem. Soc. 2010, 239, 389-ORGN
Aziridination of Tethered Allenes

C North, J Robertson,
Abstr. Pap. Am. Chem. Soc. 2009, 237, 523-ORGN
Studies on the Total Synthesis of the Lituarines

W P Unsworth, J Robertson, S Lamont,
Abstr. Pap. Am. Chem. Soc. 2009, 237, 75-ORGN
Rhodium(II) Catalyzed Oxyamination Reactions in the Synthesis of Malayamycin A

D Woollaston, J Robertson,
Abstr. Pap. Am. Chem. Soc. 2006, 232, 913-ORGN
Natural Product Synthesis via the Oxidation of Furan Derivatives

M Menard, J Robertson, R Ford, Abstr. Pap. Am. Chem. Soc. 2003, 225, 434-ORGN
Asymmetric Synthesis of Substituted Cyclopentenone Derivatives

J Robertson, J Pillai, Abstr. Pap. Am. Chem. Soc. 1998, 215(2), 310-ORGN
Heterocycle Synthesis by Hydrogen Atom Abstraction and Cyclisation

J Robertson, G O’Connor, Abstr. Pap. Am. Chem. Soc. 1997, 213(2), 461-ORGN
Silicon Tethered Ene Cyclisations

K Tchabanenko, J Robertson,
Abstr. Pap. Am. Chem. Soc. 1997, 213(2), 113-ORGN
Studies Towards the Total Synthesis of Nagstatin

J Robertson, J N Burrows, Abstr. Pap. Am. Chem. Soc. 1996, 211(2), 448-ORGN
Studies Towards the Total Synthesis of Roseophilin