Independent publications
100) Y Zhang, Z Xiong, Y Li, M Wilson, K E Christensen, E Jacques, P Hernández-Lladó, J Robertson, L L Wong, Nat. Synth. 2022, 1, 936
Enantioselective Oxidation of Unactivated C–H Bonds in Cyclic Amines by Iterative Docking-Guided Mutagenesis of P450BM3 (CYP102A1)
See the associated Research Briefing: Accelerated Enzyme Evolution for Targeted C–H Oxidation in Cyclic Amines on page 921 of the December issue
99) D J Dearlove, D Holdsworth, T Kirk, L Hodson, E Charidemou, E Kvalheim, B Stubbs, A Beevers, J L Griffin, R Evans, J Robertson, K Clarke, P J Cox, Front. Med. 2021, 8, 721673
beta-Hydroxybutyrate Oxidation in Exercise is Impaired by Low-Carbohydrate and High-Fat Availability
98) A W Sobanska, J Robertson, E Brzezinska, Pharmaceuticals 2021, 14, 600
RP-18 TLC Chromatographic and Computational Study of Skin Permeability of Steroids
97) V A Palchykov, P C Dale, J Robertson, New J. Chem. 2021, 45, 9020
Nucleophilic Vinylic Substitution in Bicyclic Methyleneaziridines: SNVpi or SNVsigma?
96) A W Sobanska, J Robertson, E Brzezinska, Pharmaceuticals 2021, 14, 147
Application of RP-18 TLC Retention Data to Prediction of Transdermal Absorption of Drugs
95) W J M Lewis, D M Shaw, J Robertson, Beilstein J. Org. Chem. 2021, 17, 334
Synthesis of Legonmycins A and B, C(7a)-Hydroxylated Bacterial Pyrrolizidines
94) L A Harwood, L L Wong, J Robertson, Angew. Chem. Int. Ed. 2021, 60, 4434
Enzymatic Kinetic Resolution by Addition of Oxygen
93) K Y Seah, J Robertson, Tetrahedron Lett. 2020, 61, 152170
Enantioselective Synthesis of C(9) Hydroxy Analogues of Hederacines A and B
92a) Structural correction in: Tetrahedron Lett. 2020, 61, 151497
Corrigendum to "A 6/5/5/7 Heterotetracyclic Indole Derivative Alkaloid Isolated from Typhonium Giganteum"
92) J Zhou, J-H Feng, J Robertson, L Fang, Bioorg. Med. Chem. Lett. 2020, 30, 127294
Corrigendum to "A Novel Monoterpenoid Indole Alkaloid with Anticancer Activity from Melodinus Khasianus"
91) K Y Seah, J Robertson, Tetrahedron 2019, 75, 130661
Investigation of an Annulation-Fragmentation-Spirocyclisation Approach to Fawcettimine-type Lycopodium Alkaloids
90) J T R Liddon, P J Lindsay-Scott, J Robertson, J. Org. Chem. 2019, 84, 13790
Secondary Products from Intramolecular Cycloadditions of Azidoalkyl Enol Ethers and Azidoalkyl Vinyl Bromides. 1-Azadienes, their Reactions with Diphenylketene, and Radical Cyclizations to form Bi- and Tricyclic Lactams
89) L-D Syntrivanis, L L Wong, J Robertson, Eur. J. Org. Chem. 2018, 6369
Hydroxylation of Eleuthoside Synthetic Intermediates by P450BM3 (CYP102A1)
88) L-D Syntrivanis, F J. del Campo, J Robertson, J. Flow Chem. 2018, 8, 123
An Electrochemical Flow Cell for the Convenient Oxidation of Furfuryl Alcohols
87) J O'Hanlon, X Ren, M Morris, L L Wong, J Robertson, Org. Biomol. Chem. 2017, 15, 8780
Hydroxylation of Anilides by Engineered Cytochrome P450BM3
86) L-D Syntrivanis, J Robertson, Eur. J. Org. Chem. 2017, 4916
Synthesis of (E)-4-Methylhexa-3,5-dienol and its Diels–Alder Reaction with Thioester Dienophiles: a Short Enantioselective Synthesis of Bicyclic Lactones
85) O Zhurakovskyi, S R Ellis, A L Thompson, J Robertson, Org. Lett. 2017, 19, 2174
Access to a Guanacastepene and Cortistatin-Related Skeleton via Ethynyl Lactone Ireland–Claisen Rearrangement and Transannular (4+3)-Cycloaddition of an Azatrimethylenemethane Diyl
84) J Robertson, K Stevens, Nat. Prod. Rep. 2017, 34, 62
Pyrrolizidine Alkaloids: Occurrence, Biology, and Chemical Synthesis
83) B Martin, J Sedelmeier, A Bouisseau, P Fernandez-Rodriguez, J Haber, F Kleinbeck, S Kamptmann, F Susanne, P Hoehn, M Lanz, L Pellegatti, F Venturoni, J Robertson, M C Willis, B Schenkel, Green Chem. 2017, 19, 1439
Toolbox Study for Application of Hydrogen Peroxide as a Versatile, Safe and Industrially-relevant Green Oxidant in Continuous Flow Mode
82) X Ren, J A O'Hanlon, M Morris, J Robertson, L L Wong, ACS Catal. 2016, 6, 6833
Imidazolidin-4-ones via a Cytochrome P450-Catalyzed Intramolecular C-H Amination
81) A J Murray,N S Knight, M A Cole, L E Cochlin, E Carter, K Tchabanenko, T Pichulik, M K Gulston, H J Atherton, M A Schroeder, R M J Deacon, Y Kashiwaya, M T King, R Pawlosky, J N P Rawlins, D J Tyler, J L Griffin, J Robertson, R L Veech, K Clarke, FASEB J. 2016, 30, 4021
Novel Ketone Diet Enhances Physical and Cognitive Performance
80) M Liebeke, N Strittmatter, S Fearn, A J Morgan, P Kille, J Fuchser, D Wallis, V Palchykov, J Robertson, E Lahive, D J Spurgeon, D McPhail, Z Takats, J G Bundy, Nat. Commun. 2015, 6:7869
Unique Metabolites Protect Earthworms Against Plant Polyphenols
79) V A Pal'chikov, J Robertson, Russ. J. Org. Chem. 2014, 50, 1369 [Zh. Org. Khim. 2014, 50, 1384]
Efficient Procedure for the Preparation of 2-Bromo-5-ethylfuran and its Unexpected Isomerization
78) W P Unsworth, N Clark, T O Ronson, K Stevens, A L Thompson, S G Lamont, J Robertson, Chem. Commun. 2014, 50, 11393
Rhodium(II)-Catalysed Tandem Aziridination and Ring-opening: Stereoselective Synthesis of Functionalised Tetrahydrofurans
77) J Robertson, K Stevens, Nat. Prod. Rep. 2014, 31, 1721
Pyrrolizidine Alkaloids
76) W P Unsworth, S G Lamont, J Robertson, Tetrahedron 2014, 70, 7388
Substrate Scope and Stereocontrol in the Rh(II)-Catalysed Oxyamination of Allylic Carbamates
75) K Y Seah, S J Macnaughton, J W P Dallimore, J Robertson, Org. Lett. 2014, 16, 884
Synthesis of Pandamarilactone-1
74) B Wu, G C Feast, A L Thompson, J Robertson, J. Org. Chem. 2012, 77, 10623
Synthesis of Stereoisomers of Artemisia and Chrysanthemum Bis(acetylenic) Enol Ether Spiroacetals
73) K Clarke, K Tchabanenko, R Pawlowsky, E Carter, M T King, K Musa-Veloso, M Ho, A Roberts, J Robertson, T B VanItallie, R L Veech, Regul. Toxicol. Pharmacol. 2012, 63, 401
Kinetics, Safety and Tolerability of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate in Healthy Adult Subjects
72) K Clarke, K Tchabanenko, R Pawlowsky, E Carter, N S Knight, A J Murray, L E Cochlin, M T King, A W Wong, A Roberts, J Robertson, R L Veech, Regul. Toxicol. Pharmacol. 2012, 63, 196
Oral 28-Day and Developmental Toxicity Studies of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate
71) O Zhurakovskyi, J Robertson, Abstr. Pap. Am. Chem. Soc. 2012, 243, 578-ORGN
Pericyclic Rearrangements of Tethered Allene Azides [abstract]
70) S Naud, S J Macnaughton, B S Dyson, D J Woollaston, J W P Dallimore, J Robertson, Org. Biomol. Chem. 2012, 10, 3506
Conformational Preferences of Oxy‐ Substituents in Butenolide‐tetrahydropyran Spiroacetals and Butenolide‐piperidine Spiro‐N,O‐acetals
69) K Stevens, A J Tyrrell, S Skerratt, J Robertson, Org. Lett. 2011, 13, 5964
Synthesis of NP25302
68) W P Unsworth, K Stevens, S G Lamont, J Robertson, Chem. Commun. 2011, 47, 7659
Stereospecificity in the Au-Catalysed Cyclisation of Monoallylic Diols. Synthesis of (+)-Iso-altholactone
67) K Stevens, J Robertson, Abstr. Pap. Am. Chem. Soc. 2011, 241, 255-ORGN
Total Synthesis of the Pyrrolizidine Alkaloid Natural Product NP25302 [abstract]
66) J Robertson, C North, J E R Sadig, Tetrahedron 2011, 67, 5011
Asymmetric Synthesis of the C(6–18) Bis(tetrahydropyran)spiroacetal Fragment of the Lituarines
65) J Robertson, K Clarke, R L Veech, WO 2010/120300 also US 9034613 B2 (2015)
Process for the Preparation of (3R)-Hydroxybutyl (3R)-hydroxybutyrate by Enzymatic Enantioselective Reduction Employing Lactobacillus brevis Alcohol Dehydrogenase
64) J W Levell, J P Gunning, P L Burn, J Robertson, I D W Samuel, Org. Electron. 2010, 11, 1561
A Phosphorescent Poly(dendrimer) with Increased Viscosity for Solution-Processed OLED Devices
63) B Wu, A Mallinger, J Robertson, Org. Lett. 2010, 12, 2818
Synthesis of Taurospongin A
62) S Macnaughton, J Robertson, J Dallimore, Abstr. Pap. Am. Chem. Soc. 2010, 239, 1066-ORGN
Development of an Extended Aza-Achmatowicz Cyclisation: Progress Towards the Total Synthesis of Pandamarilactone-1 [abstract]
61) G C Feast, J Robertson, L W Page, Abstr. Pap. Am. Chem. Soc. 2010, 239, 389-ORGN
Aziridination of Tethered Allenes [abstract]
60) J Robertson, G C Feast, L V White, V A Steadman, T D W Claridge, Org. Biomol. Chem. 2010, 8, 3060
Structure and Reactivity of Bicyclic Methylene Aziridines Prepared by Intramolecular Aziridination of Allenes
59) J P Gunning, J W Levell, M F Wyatt, P L Burn, J Robertson, I D W Samuel, Polymer Chem. 2010, 1, 730
The Development of Poly(dendrimers) for Advanced Processing
58) G C Feast, L W Page, J Robertson, Chem. Commun. 2010, 46, 2835
The Intramolecular Amination of Allenes
57) J Robertson, W P Unsworth, S G Lamont, Tetrahedron 2010, 66, 2363
Aspects of Stereocontrol in the L-Selectride Reduction of 4-Acyl-1,3-dioxolane Derivatives
56) J Robertson, P T Chovatia, T G Fowler, J M Withey, D J Woollaston, Org. Biomol. Chem. 2010, 8, 226
Oxidative Spirocyclisation Routes Towards the Sawaranospirolides. Synthesis of ent-Sawaranospirolides C and D
55) G C Feast, J Haestier, L W Page, J Robertson, A L Thompson, D J Watkin, Acta. Cryst. 2009, C65, o635
An Unusual Methylene Aziridine Refined in P21/c and the Nonstandard Setting P21/n
54) J Robertson, A J Tyrrell, P T Chovatia, S Skerratt, Tetrahedron Lett. 2009, 50, 7141
Synthesis of Pyrrolidin-3-ones from Dihydropyran Precursors via Spiro-N,O-acetals
53) C North, J Robertson, Abstr. Pap. Am. Chem. Soc. 2009, 237, 523-ORGN
Studies on the Total Synthesis of the Lituarines [abstract]
52) W P Unsworth, J Robertson, S Lamont, Abstr. Pap. Am. Chem. Soc. 2009, 237, 75-ORGN
Rhodium(II) Catalyzed Oxyamination Reactions in the Synthesis of Malayamycin A [abstract]
51) J Robertson, E Abdulmalek, Tetrahedron Lett. 2009, 50, 3516
Concerning Directed Oxidation and Transacylation During a General Approach to Hydroxylated Lactams
50) J Robertson, M J Hall, S P Green, Tetrahedron 2009, 65, 5541
Stereospecific α-Methallylation of Hydroxy-aldehydes by Silatropic Ene Cyclisation
49) J Robertson, In Elegant Total Synthesis, Wiley-VCH, Weinheim, 2009, K J Hale (ed.)
Chapter 9, Saturated Alkaloid Synthesis [book chapter, under review]
48) J Robertson, S Naud, Org. Lett. 2008, 10, 5445
Synthesis of Spiroacetal Enol Ethers by Oxidative Activation of Furan Derivatives
47) J Robertson, M J Palframan, S A Shea, K Tchabanenko, W P Unsworth, C Winters, Tetrahedron 2008, 64, 11896
Radical 1,4-Aryl Transfer in Arylcarboxamides Leading to Phthalimides, Biaryls, and Enantiomerically Enriched β-Arylethylamines
46) A J Tyrrell, G C Feast, J Robertson, Acta. Cryst. 2008, E64, o1261
(1RS, 4SR)-1,4-Dimethyl-3-dichloromethylene-2-oxabicyclo[2.2.2]oct-5-ene
45) J Robertson, K Stevens, S Naud, Synlett 2008, 2083
Synthesis of Pyrenolide D Analogues
44) J Robertson, S P Green, M J Hall, A J Tyrrell, W P Unsworth, Org. Biomol. Chem. 2008, 6, 2628
Further Studies on Silatropic Carbonyl Ene Cyclisations: β-Crotyl(diphenyl)silyloxy Aldehyde Substrates; Synthesis of 2-Deoxy-2-C-phenylhexoses
43) J Robertson, T G Fowler, Org. Biomol. Chem. 2006, 4, 4307
Synthesis and Claisen Rearrangement of Bridged Bicyclic Enol Ethers of Relevance to the Course of Ketene s-cis-Diene Cycloaddition
42) M J Palframan, K Tchabanenko, J Robertson, Tetrahedron Lett. 2006, 47, 8423
Aryl Pyrrolidinones via Radical 1,4-Aryl Migration and 5-endo-trig Cyclisation of N-(2-bromoallyl)arylcarboxamides
41) D Woollaston, J Robertson, Abstr. Pap. Am. Chem. Soc. 2006, 232, 913-ORGN
Natural Product Synthesis via the Oxidation of Furan Derivatives [abstract]
40) J Robertson, A J Tyrrell, S Skerratt, Tetrahedron Lett. 2006, 47, 6285
Oxidation Products of 2-Acyl-4,5-dihydrofurans
39) J Robertson, S J Bell, A Krivokapic, Org. Biomol. Chem. 2005, 3, 4246
On the Reaction of Diphenylketene with Isocyanides
38) J Robertson, J W P Dallimore, Org. Lett. 2005, 7, 5007
Progress in the Synthesis of the Lituarines: Stereocontrol in Sequential C–C Bond Formation on a Spirobutenolide Template
37) J Robertson, P M Stafford, S J Bell, J. Org. Chem. 2005, 70, 7133
Silatropic Carbonyl Ene Cyclisations in the Synthesis of Pseudosugars and Hydroxylated Piperidines
36) J Robertson, B M Doyle, C Hoarau, P Meo, Org. Lett. 2004, 6, 3861
Stereoselective Synthesis of the Lituarine Tricyclic Spiroacetal
35) J Robertson, J W P Dallimore, P Meo, Org. Lett. 2004, 6, 3857
Syntheses of the C(1–6) and C(19–24) Fragments of Lituarines A, B, and C
34) J Robertson, M Menard, R Ford, Synlett 2004, 2788
An Approach to the Tricyclic Lactone Core of Brasoside and Related Natural Products
33) J Robertson, M Menard, R Ford, Org. Biomol. Chem. 2004, 2, 2988
Conjugate Addition of Organocopper Reagents to γ-Alkoxybutenolides and Application to the Synthesis of Non-racemic Alkyl Cyclopentenones
32) J Robertson, M J Hall, P M Stafford, S P Green, Org. Biomol. Chem. 2003, 1, 3758
Ene Cyclisations of α-(Prenyl)dialkylsilyloxy Aldehydes: Formation and Oxidative Cleavage of Oxasilacyclohexanols
31) J Robertson, M J Hall, S P Green, Org. Biomol. Chem. 2003, 1, 3635
Stereospecificity in the Silicon Tethered α-(Methyl)allylation of Aldehydes
30) J Robertson and P M Stafford, In Carbohydrates, Academic Press, Place, 2003, H M I Osborn (ed), Chapter 1, Selective Hydroxyl Protection and Deprotection [book]
29) M Menard, J Robertson, R Ford, Abstr. Pap. Am. Chem. Soc. 2003, 225, 434-ORGN
Asymmetric Synthesis of Substituted Cyclopentenone Derivatives [abstract]
28) J Robertson, Times Higher Education Supplement, January 4th 2002
Watch Out for Bearded Geezer [book review]
27) J Robertson, J Pillai, R K Lush, Chem. Soc. Rev. 2001, 30, 94
Radical Translocation Reactions in Synthesis
26) J Robertson, H-W Lam, S Abazi, S L Roseblade, R K Lush, Tetrahedron 2000, 56, 8959
Radical Cascade Processes Leading to Fused- and Spiro-bicyclic Ring Systems
25) J Robertson, R J D Hatley, D J Watkin, J. Chem. Soc., Perkin Trans. 1 2000, 3389
Preparation of the Tricyclic Ketopyrrole Core of Roseophilin by Radical Macrocyclisation and Paal–Knorr Condensation
24) J Robertson, G O’Connor, C L Ringrose, D S Middleton, Tetrahedron 2000, 56, 8321
Silicon Tethered Alkenyl Transfer and Type I Ene Cyclisations
23) J Robertson, G O’Connor, T Sardharwala, D S Middleton, Tetrahedron 2000, 56, 8309
Stereoselective Synthesis of Silacyclohexanols by Silicon Tethered Type II Ene Cyclisation
22) J Robertson, N Kuhnert, Y Zhao, Heterocycles 2000, 53, 2415
Synthesis of 3-Chloro-2-formylpyrrole Derivatives
21) J Robertson, Protecting Group Chemistry, Oxford University Press, Oxford, 2000 [book]
20) J Robertson, In The Chemical Synthesis of Natural Products, Sheffield Academic Press, Sheffield, 2000, K J Hale (ed.), Chapter 4, Important Developments in the Total Synthesis of Alkaloids [book]
19) J Robertson, R J D Hatley, J. Chem. Soc., Chem. Commun. 1999, 1455
Formal Synthesis of Roseophilin
18) N Kuhnert, J Peverley, J Robertson, Tetrahedron Lett. 1998, 39, 3215
Bistrifluoromethanesulfonimide in the Catalytic Conjugate Allylation of α,β-Unsaturated Carbonyl Compounds
17) J Robertson, D S Middleton, G O’Connor, T Sardharwala, Tetrahedron Lett. 1998, 39, 669
Oxasilacyclopentanes as Intermediates for Silicon Tethered Ene Cyclisations
16) J Robertson, J Pillai, Abstr. Pap. Am. Chem. Soc. 1998, 215(2), 310-ORGN
Heterocycle Synthesis by Hydrogen Atom Abstraction and Cyclisation [abstract]
15) J Robertson, J N Burrows, Synthesis 1998, 63
Preparation and Reactivity of 2-Cyclodecynone
14) J Robertson, J N Burrows, P A Stupple, Tetrahedron 1997, 53, 14807
Bicyclo[10.2.1]pentadecenone Derivatives by Free Radical Macrocyclisation
13) J Robertson, G O’Connor, Abstr. Pap. Am. Chem. Soc. 1997, 213(2), 461-ORGN
Silicon Tethered Ene Cyclisations [abstract]
12) K Tchabanenko, J Robertson, Abstr. Pap. Am. Chem. Soc. 1997, 213(2), 113-ORGN
Studies Towards the Total Synthesis of Nagstatin [abstract]
11) J Robertson, M A Peplow, J Pillai, Tetrahedron Lett. 1996, 37, 5825
The Synthesis of (±)-Heliotridane and (6S,7S)-Dihydroxyheliotridane via Sequential Hydrogen Atom Abstraction and Cyclisation
10) J Robertson, G O’Connor, D S Middleton, Tetrahedron Lett. 1996, 37, 3411
Silicon Tethered Type II Ene Cyclisations
9) J Robertson, J N Burrows, Abstr. Pap. Am. Chem. Soc. 1996, 211(2), 448-ORGN
Studies Towards the Total Synthesis of Roseophilin [abstract]
8) J Robertson, J N Burrows, Tetrahedron Lett. 1994, 35, 3777
Free Radical Rearrangement of Alkenyl Epoxy Silanes. Isolation of α-Trimethylsilyl Aldehydes
• Postdoctoral research
7) T Doi, J Robertson, G Stork, A Yamashita, Tetrahedron Lett. 1994, 35, 1481
Regiospecificity in the Cyclization of 6-(1-Hydroxyalkyl) Geraniol Derivatives. A Simple Route to the Taxol A-ring System
• Graduate research
6) J E Baldwin, R M Adlington, J Robertson, Tetrahedron 1991, 47, 6795
Carbocyclic Ring Expansion Reactions via Radical Chain Processes. Part II
5) J E Baldwin, R M Adlington, M B Mitchell, J Robertson, Tetrahedron 1991, 47, 5901
Intramolecular SH2’ Macrocyclisations
4) J E Baldwin, R M Adlington, M B Mitchell, J Robertson, J. Chem. Soc., Chem. Commun. 1990, 1574
Radical Reactions in Organic Synthesis: Intramolecular SH2’ Macrocyclisations
3) J E Baldwin, R M Adlington, J Robertson, Tetrahedron 1989, 45, 909
Carbocyclic Ring Expansion Reactions via Radical Chain Processes
2) J E Baldwin, R M Adlington, J Robertson, J. Chem. Soc., Chem. Commun. 1988, 1404
Carbocyclic Ring Expansion Reactions via Radical Chain Processes
• Undergraduate research
1) L M Harwood, J Robertson, Tetrahedron Lett. 1987, 28, 5175
Preparation of Cyclic Ethers via Oxidative Cyclisation of 2-(4-Hydroxyalkyl)- and (5-Hydroxyalkyl)furans with DDQ