Our research comes under the broad heading of the chemistry of Carbohydrates and Proteins. The reactions and manipulation of sugars and proteins have fascinated organic chemists for over a century and this work is culminating today in a host of new drugs for treating diseases.
It is becoming increasingly clear that oligosaccharides (carbohydrates in small clusters) and alterations in proteins (modifications) are examples of chemically complex biological markers that act critcially in important extracellular and organismal processes such as immune response, microbial infection, cancer metastasis and cellular adhesion, inflammation, in addition to vital intracellular communication events such as epigenetics and signalling cascades. Their remarkable structural diversity means that they can often mediate highly specific and therefore complex processes. The application of an understanding of such systems on a fundamental level leads to the design, synthesis and modification of potential therapeutic and biotechnologically applicable systems.
In January 2004 we moved from the Dyson Perrins Laboratory to the new Chemistry Research Laboratory. You can explore the Virtual Tour of the CRL, in particular the 360° paroramas of our write-up area and one of our lab (Quicktime software required).
Our research is supported by the EPSRC, the BBSRC, the MRC, the Gates Foundation, UCB-Celltech, Pfizer, AstraZeneca, the EU, Glycovaxyn, Cancer Research UK, and the Royal Society.
Last updated: 11-11-2014
Matt Bilyard has been given a Lilly Prize for his 1st year Graduate Defence / PRS Transfer
Costi Giurgiu has been given a GSK Prize in Practical Organic Chemistry
The group CLICK-gong was featured on Lewis Episode 1, Series 8.
Ben Davis gave the 2014 Bender Distinguished Summer Lectures at Northwestern University.
Lingbing Kong's paper on a new antibiotic strategy was the cover of Nature Chemistry.News archives
Prof Ben G. Davis
University of Oxford
Chemistry Research Laboratory
Oxford, OX1 3TA, UK
Phone: + 44 (0)1865 275652
Fax: + 44 (0)1865 275674