Our research comes under the broad heading of the chemistry of Carbohydrates and Proteins. The reactions and manipulation of sugars and proteins have fascinated organic chemists for over a century and this work is culminating today in a host of new drugs for treating diseases.
It is becoming increasingly clear that oligosaccharides (carbohydrates in small clusters) and alterations in proteins (modifications) are examples of chemically complex biological markers that can act in important recognition processes such as microbial infection, cancer metastasis and cellular adhesion in inflammation, in addition to many intracellular communication events. Their remarkable structural diversity means that they can often mediate highly specific and therefore complex processes. The application of an understanding of such systems on a fundamental level leads to the design, synthesis and modification of potential therapeutic and biotechnologically applicable systems.
In January 2004 we moved from the historical Dyson Perrins Laboratory to the new Chemistry Research Laboratory. You can explore the Virtual Tour of the CRL, in particular the 360° paroramas of our write-up area and one of our lab (Quicktime software required).
Last updated: 07-10-09
Latest publication
News
Work by Justin Chalker, Angel Lin and Omar Boutureira from the group on protein cross metathesis that appears in Chem. Commun. as a hot article has been highlighted by the RSC's popular science news magazine Chemical Science.
Keriann Backus, a 2nd year student from the group and part of the joint NIH-Oxford programme, was awarded the 'Pfizer Outstanding Poster Prize' at the Bioorganic Gordon Conference held at the Proctor Academy, June 14-19, 2009. Samantha Shanley, a 4th year student from the group was also awarded the Jeremy R. Knowles Memorial Travel Scholarship to attend the same GRC.
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Prof Ben G. Davis
University of Oxford
Chemistry Research Laboratory
Mansfield Road
Oxford, OX1 3TA, UK
Phone: + 44 (0)1865 275652
Fax: + 44 (0)1865 275674
Ben.Davis@chem.ox.ac.uk
