Photo-Induced, Family-Specific, Site-Selective Cleavage of TIM-barrel Proteins

Thiyl-Glycosylation of Olefinic Proteins: S-linked Glycoconjugate Synthesis

Accessible Sugars as Asymmetric Olefin Epoxidation Organocatalysts: Glucosaminide Ketones in the Synthesis of Terminal Epoxides

A Potent Fluoro-Oligosaccharide Probe of Toxoplasmosis Adhesion

Saturation Transfer Difference NMR Reveals Functionally Essential Kinetic Differences for a Sugar Binding Repressor Protein

Detailed Insights from Microarray and Crystallographic Studies into Carbohydrate Recognition By Microneme Protein 1 (MIC1) of Toxoplasma gondii

The Building Blocks of Cellulose: The Intrinsic Conformational Structures of Cellobiose, Its Epimer, Lactose, and Their Singly Hydrated Complexes

Site-Selective Chemical Protein Glycosylation Protects from Autolysis and Proteolytic Degradation

Sugar Synthesis in a Protocellular Model Leads to a Cell Signalling response in Bacteria

Enabling Olefin Metathesis on Proteins: Chemical Methods for Installation of S-Allyl Cysteine

Rewritable Glycochips

Conformational Change and Selectivity in Explicitly Hydrated Carbohydrates

A Silver-Lined Anniversary of Fleet Iminosugars: 1984-2009, from DIM to DRAM to LABNAc

The Linear Assembly of a Pure Glycoenzyme

Olefin Metathesis for Site-Selective Protein Modification

Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology

Systemic Inflammatory Response Reactivates Immune-Mediated Lesions in Rat Brain

Carbohydrate-Aromatic Interactions: A Computational and IR Spectroscopic Investigation of the Complex, Methyl &alpha-L-Fucopyranoside·Toluene, Isolated in the Gas Phase

Sugars & Proteins: New Strategies in Synthetic Biology

Peptide Secondary Structures in the Gas Phase: Consensus Motif of N-linked Glycoproteins

High Purity Discrete PEG Oligomer Crystals Allow Structural Insight

Core-Shell PbI2@WS2 Nanotubes from Capillary Wetting

Glyconanoparticles Allow Pre-symptomatic In Vivo Imaging of Brain Disease

Glycoprotein Synthesis: An Update

Probing the Glycosidic Linkage: Secondary Structures in the Gas Phase

Conformational Choice and Selectivity in Singly and Multiply Hydrated Monosaccharides in the Gas Phase

Glycomimetic Inhibitors of Mycobacterial Glycosyltransferases: Targeting the TB Cell Wall

Solvent Interactions and Conformational Choice in a Core N-Glycan Segment: Gas Phase Conformation of the Central, Branching Trimannose Unit and its Singly Hydrated Complex

Allyl Sulfides are Privileged Substrates in Aqueous Cross-Metathesis: Application to Site-Selective Protein Modification

Reagent Switchable Stereoselective β(1,2) Mannoside Mannosylation: OH-2 of Mannose is a Privileged Acceptor

Chemical Site-Selective Prenylation of Proteins

Facile Conversion of Cysteine and Alkyl Cysteines to Dehydroalanine on Protein Surfaces: Versatile and Switchable Access to Functionalized Proteins

Chemical Approaches to Mapping the Function of Post-Translational Modifications

From Disulfide- to Thioether-linked Glycoproteins

Site-Selective Glycosylation of Proteins: Creating Synthetic Glycoproteins

Removal of Amorphous Carbon for the Efficient Sidewall Functionalisation of Single-Walled Carbon Nanotubes

Atomic-Scale Detection of Organic Molecules Coupled to Single-Walled Carbon Nanotubes

Enzymatic Glycosynthesis GeTs Better

A Trisulfide-linked Glycoprotein

Chemical and Chemoezymatic Synthesis of Glycosyl-Amino Acids and Glycopeptides Related to Trypanosoma cruzi Mucins

Carbohydrate Molecular Recognition: A Spectroscopic Investigation of Carbohydrate-Aromatic Interactions

Discovery of a Glycosynthase-Catalyst for Synthesis of Flavonoid Glycosides

IR-Spectral Signatures of Aromatic-Sugar Complexes: Probing Carbohydrate-Protein Interactions

Expanding the Diversity of Chemical Protein Modification Allows Post-Translational Mimicry

Folding of an MHC class II-restricted Tumor Antigen Controls its Antigenicity via MHC-guided Processing

The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity

The Imitation Game—A Computational Chemical Approach to Recognizing Life

Direct Formation of Glycosyl Thiols from Reducing Sugars Allows One-pot Protein Glycoconjugation

Unique Regulation of the Active site of the Serine Esterase S-Formylglutathione Hydrolase

The Expanding Roles of Biocatalysis and Biotransformation

Direct Deprotected Glycosyl-Asparagine Ligation

Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification

Building Up Key Segments of N-Glycans in the Gas Phase: Intrinsic Structural Preferences of the α(1,3) and α(1,6) Dimannosides

Carbohydrate-Derived Amino-Alcohol Ligands for Asymmetric Alkynylation of Aldehydes

Exploring and Exploiting the Therapeutic Potential of Glycoconjugates

Spectral Signatures of Structural Motifs in Isolated and Hydrated Monosacharides: phenyl α- and β-L-fucopyranoside

Glycosyldisulfides: Novel Glycosylating Reagents with Flexible Aglycon Alteration

Diversification in Substrate Usage by Glutathione Synthetases from Soya Bean (Glycine max), wheat (Triticum aestivum) and maize (Zea mays)

A Carbohydrate-Antioxidant Hybrid Polymer Reduces Oxidative Damage in Spermatozoa and Enhances Fertility

Ligand Amplification in a Dynamic Combinatorial Glycopeptide Library

Hydrogen Bonding and Cooperativity in Isolated and Hydrated Sugars: Mannose, Galactose, Glucose, and Lactose

Structural Dissection and High-Throughput Screening of Mannosylglycerate Synthase

Probing the Breadth of Glycosyltransferases: In Vitro Remodeling of a Polyketide Antibiotic Creates Active Bacterial Uptake and Enhances Potency

Adding Water to Sugar: A Spectroscopic and Computational Study of α- and β-Phenylxyloside in the Gas Phase

A Tuneable Method for N-Debenzylation of Benzylamino Alcohols

Lectins: Tools for the Molecular Understanding of the Glycocode

Developing Promiscuous Glycosidases for Glycoside Synthesis: Residues W433 and E432 in Sulfolobus solfataricus β-Glycosidase are Important Glucoside- and Galactoside-Specificity Determinants

Investigation of the Interaction Between Peanut Agglutinin and Synthetic Glycopolymeric Multivalent Ligands

Glycoviruses: Chemical Glycosylation Retargets Adenoviral Gene Transfer

High-Throughput Mass-Spectroscopy Monitoring for Substrate Enzymes: Determining the Kinetic Parameters and Catalytic Activities of Glycosyltransferases

Glyco- and Peptidomimetics from Three-Component Jouillé-Ugi Coupling Show Selective Antiviral Activity

"Polar Patch" Proteases as Glycopeptiligases

Carbohydrate-derived Aminoalcohol Ligands for Asymmetric Reformatsky Reactions

LEAPT: Lectin-directed Enzyme Activated Prodrug Therapy

Selective Electrochemical Glycosylation by Reactivity Tuning

Plasmachemical Surface Functionalised Beads: Versatile Tailored Supports for Polymer Assisted Organic Synthesis

Modular Control of Lectin Function: Redox-Switchable Agglutination

Glycodendriproteins: a Synthetic Glycoprotein Mimic Enzyme with Branched Sugar-display Potently Inhibits Bacterial Aggregation

Comparison of the Effect of Pore Architecture and Bead Size on the Extent of Plasmachemical Amine Functionalisation of Poly(styrene-co-divinylbenzene) Permanently Porous Resins

Mimicking Posttranslational Modifications of Proteins

Glyco-SeS: Selenenylsulfide-Mediated Protein Glycoconjugation - A New Stategy in Posttranslational Modification

Synthetic Methods: Part (III) Enzyme Methods

Precise Structure Activity Relationships in Asymmetric Catalysis Using Carbohydrate-Scaffolds to Allow Ready Fine Tuning: Dialkylzinc-Aldehyde Additions

Glycosyl Phenylthiosulfonates (Glyco-PTS): Novel Reagents for Glycoprotein Synthesis

Nitrogen Inversion as a Diastereomeric Relay in Azasugar Synthesis: the First Synthesis of Adenophorine

Chemical Modification of Biocatalysts

Highly Diastereoselective Additions to Polyhydroxylated Pyrrolidine Cyclic Imines: Ready Elaboration of Aza-Sugar Scaffolds to Create Diverse Carbohydrate-Processing Enzyme Probes

Selective Receptor Degradation by Ligand-Targeted Enzymes: Towards the Creation of Catalytic Antagonists

Solid Phase Peptide Templated Glycosidic Bond Formation

Plasmachemical Amine Functionalization of Porous Polystyrene Spheres: The Importance of Particle Size

Synthetic Methods: Part (V) Enzyme Methods

Plasmachemical Amine Functionalization of Porous Polystyrene Beads: The Importance of Pore Architecture

Chemically Modified "Polar Patch" Mutants of Subtilisin in Peptide Synthesis with Remarkably Broad Substrate Acceptance: Designing Combinatorial Biocatalysts

Functional Divergence in the Glutathione Transferase Super-Family in Plants: Identification of Two Classes with Putative Functions in Redox Homeostasis in Arabidopsis Thaliana

Towards an Unprotected Self-Activating Glycosyl Donor System: Bromobutyl Glycosides

Drug Delivery Systems Based on Sugar-Macromolecule Conjugates

The Synthesis of Glycoproteins

Novel Cyclic Sugar Imines: Carbohydrate Mimics and Easily Elaborated Scaffolds for Aza-Sugars

Influence of Preparation Procedure on Polymer Composition: Synthesis and Characterisation of Polymethacrylates Bearing β-D-Glucopyranoside and β-D-Galactopyranoside Residues

Tailoring the Substrate Specificity of the β-Glycosidase from the Thermophilic Archeon Sulfolobus solfataricus

Biocatalysis and Enzymes in Organic Synthesis

A Simple Method for the Quantitative Analysis of Resin Bound Thiol Groups

Ready Protease-Catalyzed Synthesis of Carbohydrate-Peptide Conjugates

Glycosylation of the Primary Binding Pocket of a Subtilisin Protease Causes a Remarkable Broadening in Stereospecificity in Peptide Synthesis

Expanding the Utility of Proteases in Synthesis: Broadening the Substrate Acceptance in Non-Coded Amide Bond Formation Using Chemically Modified Mutants of Subtilisin

The Controlled Glycosylation of a Protein with a Bivalent Glycan: Towards a New Class of Glycoconjugates, Glycodendriproteins

Glycosyldisulfides: a New Class of Solution and Solid Phase Glycosyl Donors

Site-Selective Glycosylation of Subtilisin Bacillus lentus Causes Dramatic Increases in Esterase Activity

Controlled Site-Selective Protein Glycosylation for Precise Glycan Structure-Catalytic Activity Relationships

Recent Developments in Oligosaccharide Synthesis

Hand in Glove - Investigating Glycocode

Glycomethanethiosulfonates: Powerful Reagents for Protein Glycosylation

Peptide Templated Glycosylation Reactions

Recent Developments in Glycoconjugates

Altering the Specificity of subtilisin Bacillus lentus Through the Introduction of Positive Charge at Single Amino Acid Sites

The Controlled Introduction of Multiple Negative Charge at Single Amino Acid Sites in Subtilisin Bacillus lentus

Glycoprotein Synthesis: From Glycobiological Tools to Tailor-made Catalysts

Peptide Templated Glycosidic Bond Formation: a New Strategy for Oligosaccharide Synthesis

Tetrazoles of Manno- and Rhamno- Furanoses

Tetrazoles of Manno- and Rhamno- Pyranoses: Contrasting Inhibition of Mannosidases by [4.3.0] but of Rhamnosidase by [3.3.0] Bicyclic Tetrazoles

Controlled Site-Selective Glycosylation of Proteins by a Combined Site-Directed Mutagenesis and Chemical Modification Approach

5-epi-Deoxyrhamnojirimycin is a Potent Inhibitor of an α-L-Rhamnosidase: 5-epi-Deoxymannojirimycin is Not a Potent Inhibitor of an α-D-Mannosidase

Caesium Trifluoroacetate Displacement of Triflates in the Inversion of Alcohols

Inhibition of Naringinase (L-Rhamnosidase) by Piperidine Analogues of L-Rhamnose - Scaffolds for Libraries Incorporating Trihydroxypipecolic Acids

L-(+)-Swainsonine and Other Pyrrolidine Inhibitors of Naringinase - Through an Enzymatic Looking-Glass from D-Mannosidase To L-Rhamnosidase

Kinetic and Thermodynamic Azides from a-O-Triflates of g-Lactones: Intermediates for the Incorporation of Polyhydroxylated D- and L-α-Aminoacids into Combinatorial Libraries

Tetrazoles of Manno- and Rhamno- Pyranoses: Inhibition of Glycosidases by Tetrazoles and other Mannose Mimics

Tetrazoles of Manno- and Rhamno- Furanoses