Books
Carbohydrate Chemistry: OUP Chemistry Primer No. 99

B. G. Davis and A. J. Fairbanks
Oxford University Press, Oxford, 2002, ISBN: 0198558333

Publications
2014
Dissecting the Reaction of Phase II metabolites of Ibuprofen and Other NSAIDS with Human Plasma Protein
R.N. Monrad, J.C. Errey, C.S. Barry, M. Iqbal, X. Meng, L. Iddon, J.A. Perrie, J.R. Harding, I.D. Wilson, A.V. Stachulski, B.G. Davis
Chem. Sci. 2014, 5, 3789-3794 | pdf | DOI
Selective Chemical Protein Modification
C.D. Spicer, B.G. Davis
Nat. Commun. 2014, 5, 5740 | pdf | DOI
The Three Mycobacterium Tuberculosis Antigen 85 Isoforms have Unique Substrates and Activities Determined by Non-active Site Regions
K.M. Backus, M.A. Dolan, C.S. Barry, M. Joe, P. McPhie, H.I. Boshoff, T.L. Lowary, B.G. Davis, C.E. Barry
J. Biol. Chem. 2014, 289, 25041-25053 | pdf | DOI
Creation of a Gated Antibody as a Conditionally Functional Synthetic Protein
S.B. Gunnoo, H.M. Finney, T.S. Baker, A.D. Lawson, D.C. Anthony, B.G. Davis
Nat. Commun. 2014, 5, 4388 | pdf | DOI
Most Human Proteins Made in Both Nucleus and Cytoplasm Turn Over within Minutes
S. Baboo, B. Bhushan, H. Jiang, C.R. Grovenor, P. Pierre, B.G. Davis, P.R. Cook
PLoS ONE 2014, 9, e99346 | pdf | DOI
Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity
K.P. Chooi, S.R.G. Galan, R. Raj, J. McCullagh, S. Mohammed, L.H. Jones, B.G. Davis
J. Am. Chem. Soc. 2014, 136, 1698–1701 | pdf | DOI
Rationally Designed Short Polyisoprenol-Linked PglB Substrates for Engineered Polypeptide and Protein N-Glycosylation
F. Liu, B. Vijayakrishnan, A. Faridmoayer, T.A. Taylor, T.B. Parsons, G.J.L. Bernardes, M. Kowarik, B.G. Davis
J. Am. Chem. Soc. 2014, 136, 566-569 | pdf | DOI
2013
‘Naked’ and Hydrated Conformers of the Conserved Core Pentasaccharide of N-linked Glycoproteins and Its Building Blocks
C.S. Barry, E.J. Cocinero, P. Carcabal, D.P. Gamblin, E.C. Stanca-Kaposta, S.M. Remmert, M.C. Fernandez-Alonso, S. Rudic, J.P. Simons, B.G. Davis
J. Am. Chem. Soc. 2013, 135, 16895-16903 | pdf | DOI
DNA Modification under Mild Conditions by Suzuki–Miyaura Cross-Coupling for the Generation of Functional Probes
L. Lercher, J.F. McGouran, B.M. Kessler, C.J. Schofield, B.G. Davis
Angew. Chem. Intl Ed. 2013, 52, 10553-10558 | pdf | DOI
This article was selected as a 'Very Important Paper' (VIP) by the referees at Angewandte Chemie and featured in the Faculty of 1000.
Enhanced Aqueous Suzuki–Miyaura Coupling Allows Site-Specific Polypeptide 18F-Labeling
Z. Gao , V. Gouverneur, B.G. Davis
J. Am. Chem. Soc. 2013, 135, 13612-13615 | pdf | DOI
Glycomimetic Affinity-Enrichment Proteomics Identifies Partners for a Clinically-Utilized Iminosugar
I.N. Cruz, C.S. Barry, H.B. Kramer, C.C. Chuang, S. Lloyd, A.C. van der Spoel, F.M. Platt, M. Yang, B.G. Davis
Chem. Sci. 2013, 4, 3442-3446 | pdf | DOI
Realizing the Promise of Chemical Glycobiology
L.-X. Wang, B.G. Davis
Chem. Sci. 2013, 4, 3381-3394 | pdf | DOI
Rapid Cross-Metathesis for Reversible Protein Modifications via Chemical Access to Se-Allyl-selenocysteine in Proteins
Y.A. Lin, O. Boutureira , L. Lercher, B. Bhushan, R.S. Paton, B.G. Davis
J. Am. Chem. Soc. 2013, 135, 12156–12159 | pdf | DOI
This article was featured in the Faculty of 1000.
Single-Molecule Interrogation of a Bacterial Sugar Transporter Allows the Discovery of an Extracellular Inhibitor
L. Kong, L. Harrington, Q. Li, S. Cheley, B.G. Davis, H. Bayley
Nat. Chem. 2013, 5, 651-659 | pdf | DOI
This article was featured in News and Views in Nature Chemistry, in Chemistry World, in Chemical and Engineering News and in the Faculty of 1000.
‘Multicopy Multivalent’ Glycopolymer-Stabilized Gold Nanoparticles as Potential Synthetic Cancer Vaccines
A.L. Parry, N.A. Clemson, J. Ellis, S.S.R. Bernhard, B.G. Davis, N.R. Cameron
J. Am. Chem. Soc. 2013, 135, 9362–9365 | pdf | DOI
Self-Liganded Suzuki-Miyaura Coupling for Site-Selective Protein PEGylation
A. Dumas, C.D. Spicer, Z. Gao, T. Takehana, Y.A. Lin, T. Yasukohchi, B.G. Davis
Angew. Chem. Intl Ed. 2013, 52, 3916-3921 | pdf | DOI
This article was featured as a Hot Paper in Angewandte Chemie.
QuaNCAT: Quantitating Proteome Dynamics in Primary Cells
A.J.M. Howden, V. Geoghegan, K. Katsch, G. Efstathiou, B. Bhushan, O. Boutureira, B. Thomas, D.C Trudgian, B.M Kessler, D.C Dieterich, B.G. Davis, O. Acuto
Nat. Methods 2013, 10, 343-348 | pdf | DOI
Rewriting the Bacterial Glycocalyx via Suzuki–Miyaura Cross-coupling
C.D. Spicer, B.G. Davis
Chem. Commun. 2013, 49, 2747-2749 | pdf | DOI
Free Fructose Is Conformationally Locked
E.J. Cocinero, A. Lesarri, P. Écija, A. Cimas, B.G. Davis, F.J. Basterretxea, J.A. Fernández, F. Castaño
J. Am. Chem. Soc. 2013, 135, 2845–2852 | pdf | DOI
Control of Phosphoryl Migratory Transesterifications Allows Regioselecive Access to Sugar Phosphates
M.K. Patel, B.G. Davis
Org. Lett. 2013, 15, 346-349 | pdf | DOI
Inhibition of SnRK1 by Metabolites: Tissue-dependent Effects and Cooperative Inhibition by Glucose 1-phosphate in Combination with Trehalose 6-phosphate
C. Nunes, L.F. Primavesi, M.K. Patel, E. Martinez-Barajas, S.J. Powers, R. Sagar, P.S. Fevereiro, B.G. Davis, M.J. Paul
Plant Physiol. Biochem. 2013, 63, 89-98 | pdf | DOI
2012
Virus-like Glycodendrinanoparticles Displaying Quasi-equivalent Nested Polyvalency upon Glycoprotein Platforms Potently Block Viral Infection
R. Ribeiro-Viana, M. Sánchez-Navarro, J. Luczkowiak, J.R. Koeppe, R. Delgado, J. Rojo, B.G. Davis
Nat. Commun. 2012, 3, 1303 | pdf | DOI
Creation of an α-Mannosynthase from a Broad Glycosidase Scaffold
K. Yamamoto, B.G. Davis
Angew. Chem. Intl Ed. 2012, 51, 7449–7453 | pdf | DOI
Biosynthesis of the Tunicamycin Antibiotics Proceeds via Unique Exo-Glycal Intermediates
F.J. Wyszynski, S. Seo Lee, T. Yabe, H. Wang, J.P. Gomez-Escribano, M.J. Bibb, S. Jae Lee, G.J. Davies, B.G. Davis
Nat. Chem. 2012, 4, 539-546 | pdf | DOI
This article was featured in News and Views in Nature Chemistry and by the Faculty of 1000.
Conformational Effects in Sugar Ions: Spectroscopic Investigations in the Gas Phase and in Solution
R. Sagar, S. Rudić, D.P. Gamblin, E.M. Scanlan, T.D. Vaden, B. Odell, T.D.W. Claridge, J.P. Simons, B.G. Davis
Chem. Sci. 2012, 3, 2307-2313 | pdf | DOI
An Endoglycosidase with Alternative Glycan Specificity allows Broadened Glycoprotein Remodelling
J.J. Goodfellow, K. Baruah, K. Yamamoto, C. Bonomelli, B. Krishna, D.J. Harvey, M. Crispin, C.N. Scanlan, B.G. Davis
J. Am. Chem. Soc. 2012, 134, 8030-8033 | pdf | DOI
This article was featured in J. Am. Chem. Soc., as a JACS Spotlight, and also selected for "The Chemistry-Glycobiology Frontier" issue of JACS Select.
Phosphine-Free Suzuki-Miyaura Cross-Coupling in Aqueous Media Enables Access to 2-C-Aryl-Glycosides
I. Cobo, M.I. Matheu, S. Castillon, O. Boutureira, B.G. Davis
Org. Lett. 2012, 14, 1728-1731 | pdf | DOI
Conversion of Cysteine into Dehydroalanine Enables Access to Synthetic Histones Bearing Diverse Post-Translational Modifications
J.M. Chalker, L. Lercher, N.R. Rose, C.J. Schofield, B.G. Davis
Angew. Chem. Intl Ed. 2012, 51, 1835-1839 | pdf | DOI
This article was featured as a Hot Paper in Angewandte Chemie.
Palladium-mediated Cell Surface Labeling
C.D. Spicer, T. Triemer, B.G. Davis
J. Am. Chem. Soc. 2012, 134, 800-803 | pdf | DOI
This article was featured in a Highlight Article on the Use of Palladium in Biology (Suzuki Biology) in ChemBioChem.
Selenenylsulfide-Linked Homogeneous Glycopeptides and Glycoproteins: Synthesis of Human 'Hepatic Se Metabolite A'
O. Boutureira, G.J.L. Bernardes, M. Fernandez-Gonzalez, D.C. Anthony, B.G. Davis
Angew. Chem. Intl Ed. 2012, 51, 1432-1436 | pdf | DOI
2011
Carbohydrate Hydration: Heavy Water Complexes of alpha and beta Anomers of Glucose, Galactose, Fucose And Xylose
N. Mayorkas, S. Rudic, E.J. Cocinero, B.G. Davis, J.P. Simons
Phys. Chem. Chem. Phys. 2011, 13, 18671-18678 | pdf | DOI
Multi-Molecule Reaction of Serum Albumin can occur through Thiol-Yne Coupling
M. Lo Conte, S. Staderini, A. Marra, M. Sanchez-Navarro, B.G. Davis, A. Dondoni
Chem. Commun. 2011, 47, 11086-11088 | pdf | DOI
High Throughput Discovery of Heteroaromatic-Modifying Enzymes Allows Enhancement of Novobiocin Selectivity
S.M. Patel, M. de la Fuente, S. Ke, A.M.R. Guimaraes, A.O. Oliyide, X. Ji, P. Stapleton, A. Osbourn, Y. Pan, D.J. Bowles, B.G. Davis, A. Schatzlein, M. Yang
Chem. Commun. 2011, 47, 10569-10571 | pdf | DOI
Synthetic Polymers for Simultaneous Bacterial Sequestration and Quorum Sense Interference
X. Xue, G. Pasparakis, N. Halliday, K. Winzer, S.M. Howdle, C.J. Cramphorn, N.R. Cameron, P. Gardner, B.G. Davis, F. Fernandez-Trillo, C. Alexander
Angew. Chem. Intl Ed. 2011, 50, 9852-9856 | pdf | DOI
Surface Plasmon Resonance Imaging of Glycoarrays Identifies Novel and Unnatural Carbohydrate-Based Ligands for Potential Ricin Sensor Development
M. Fais, R. Karamanska, S. Allman, S.A. Fairhurst, P. Innocenti, A.J. Fairbanks, T.J. Donohoe, B.G. Davis, D.A. Russell, R.A. Field
Chem. Sci., 2011, 2, 1952-1959 | pdf | DOI
A 'Tag-and-Modify' Approach to Site-Selective Protein Modification
J.M. Chalker, G.J.L. Bernardes, B.G. Davis
Acc. Chem. Res., 2011, 44, 730-41 | pdf | DOI
Mechanistic Evidence for a Front-Side, SNi-type Reaction in a Retaining Glycosyltransferase
S. Seo Lee, S. You Hong, J.C. Errey, A. Izumi, G.J Davies and B.G Davis
Nat. Chem. Biol. 2011, 7, 631-638 | pdf | DOI
ESI-MS Assay of M. tuberculosis Cell Wall Antigen 85 Enzymes Permits Substrate Profiling and Design of a Mechanism-based Inhibitor
C.S. Barry, K.M. Backus, C.E. Barry III and B.G. Davis
J. Am. Chem. Soc. 2011, 133, 13232-13235 | pdf | DOI
Isotopic Hydration of Cellobiose: Vibrational Spectroscopy and Dynamical Simulations
M. Pincua, E.J. Cocinero, N. Mayorkas, B. Brauerd, B.G. Davis, R.B. Gerber and J.P. Simons
J. Phys. Chem. A 2011, 115, 9498-9509 | pdf | DOI
Direct Radiolabelling of Proteins at Cysteine Using [18F]-Fluorosugars
O. Boutureira, G.J.L. Bernardes, F. D'Hooge and B.G. Davis
Chem. Commun. 2011, 47, 10010-10012 | pdf | DOI
Methods for Converting Cysteine to Dehydroalanine on Peptides and Proteins
J.M. Chalker, S.B. Gunnoo, O. Boutureira, S.C. Gerstberger, M. Fernández-González, G.J.L. Bernardes, L. Griffin, H. Hailu, C.J. Schofield and B.G. Davis
Chem. Sci. 2011, 2, 1666-1676 | pdf | DOI
Site-Selective Traceless Staudinger Ligation for Glycoprotein Synthesis Reveals Scope and Limitations
G.J.L. Bernardes, L. Linderoth, K.J. Doores, O. Boutureira and B.G. Davis
ChemBioChem 2011, 12, 1383-1386 | pdf | DOI
Heavy Water Hydration of Mannose: The Anomeric Effect in Solvation, Laid Bare
N. Mayorkas, S. Rudić, B.G. Davis and J.P. Simons
Chem. Sci. 2011, 2, 1128-1134 | pdf | DOI
A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates
E.J. Grayson, G.J.L. Bernardes, J.M. Chalker, O. Boutureira, J.R. Koeppe and B.G. Davis
Angew. Chem. Intl Ed. 2011, 50, 4127-4132 | pdf | DOI
Substrate and Metal-Ion Promiscuity in Mannosylglycerate Synthase
M.M. Nielsen, M. D. L. Suits, M. Yang, C.S. Barry, C. Martinez-Fleites, L.E. Tailford, J.E. Flint, C. Dumon, B.G. Davis, H.J. Gilbert, G.J. Davies
J. Biol. Chem. 2011, 286, 15155-15164 | pdf | DOI
Uptake of Unnatural Trehalose Analogs as a Reporter for Mycobacterium tuberculosis
K.M. Backus, H.I. Boshoff, C.S. Barry, O. Boutureira, M.K Patel, F. D'Hooge, S. Seo Lee, L.E. Via, K. Tahlan, C.E. Barry III and B.G Davis
Nat. Chem. Biol. 2011, 7, 228-235 | pdf | DOI
This article was featured in Chemistry World, the University of Oxford Science Blog by the Faculty of 1000, and was highlighted in Nature and in a full Highlight Article in ChemBioChem.
Exploring Carbohydrate-Peptide Interactions in the Gas Phase: Structure and Selectivity in Complexes of Pyranosides with N-Acetylphenylalanine Methylamide
E.J. Cocinero, P. Carcabal, T.D. Vaden, B.G. Davis and J.P. Simons
J. Am. Chem. Soc. 2011, 133, 4548-4557 | pdf | DOI
Chemical Modification in the Creation of Novel Biocatalysts
A. Diaz-Rodriguez, B.G. Davis
Curr. Opin. Chem. Biol. 2011, 15, 211-219 | pdf | DOI
Palladium-Mediated Site-selective Suzuki-Miyaura Protein Modification at Genetically Encoded Aryl Halides
C.D. Spicer, B.G. Davis
Chem. Commun. 2011, 47, 1698-1700 | pdf | DOI This article was featured by the Faculty of 1000 and in a Highlight Article on the Use of Palladium in Biology (Suzuki Biology) in ChemBioChem.
Tuning the Cavity of of Cyclodextrins: Altered Sugar Adaptors in Protein Pores
W-W. Li, T.D.W. Claridge, Q. Li, M.R. Wormald, B.G. Davis and H. Bayley
J. Am. Chem. Soc. 2011, 113, 1987-2001 | pdf | DOI
Sensing the Anomeric Effect in a Solvent-Free Environment
E.J. Cocinero, P. Carcabal, T.D. Vaden, J.P. Simons and B.G. Davis
Nature 2011, 469, 76-79 | pdf | DOI
This article was featured in a Nature commentary on the future of Chemistry in the 2011 International Year of Chemistry, on the University website, and in Chemical and Engineering News.
2010
Chemical Mutagenesis: Selective Post-Expression Interconversion of Protein Amino Acid Residues
J.M. Chalker and B.G. Davis
Curr. Opin. Chem. Biol. 2010, 14, 781-789 | pdf | DOI
The Allylic Chalcogen Effect in Olefin Metathesis
Y.A. Lin and B.G. Davis
Beilstein J. Org. Chem. 2010, 6, 1219-1228 | pdf | DOI
Olefin Cross-Metathesis on Proteins: Investigation of Allylic Chalcogen Effects and Guiding Principles in Metathesis Partner Selection
Y.A. Lin, J.M. Chalker and B.G. Davis
J. Am. Chem. Soc. 2010, 132, 16805-16811 | pdf | DOI
Analysis of the Dispersity in Carbohydrate Loading of Synthetic Glycoproteins Using MALDI-TOF Mass Spectrometry
M.K. Patel, B. Vijayakrishnan, J.R. Koeppe, J.M. Chalker, K.J. Doores, B.G. Davis
Chem. Commun. 2010, 46, 9119-9121 | pdf | DOI
Site-Selective Chemoenzymatic Construction of Synthetic Glycoproteins Using Endoglycosidases
M. Fernandez-Gonzalez, O. Boutureira, G.J.L. Bernardes, J.M. Chalker, M.A. Young, J.C. Errey, B.G. Davis
Chem. Sci. 2010, 1, 709-715 | pdf | DOI
A Nonself Sugar Mimic of the HIV Glycan Shield Shows Enhanced Antigenicity
K.J. Doores, Z. Fulton, V. Hong, M.K. Patel, C.N. Scanlan, M.R. Wormald, M.G. Finn, D.R. Burton, I.A. Wilson, B.G. Davis
Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 17107-17112 | pdf | DOI
This article was highlighted in Nature Glycomics
Dissecting Tunicamycin Biosynthesis by Genome Mining: Cloning and Heterologous Expression of a Minimal Gene Cluster
F.J. Wyszynski, A.R. Hesketh, M.J. Bibb, B.G. Davis
Chem. Sci. 2010, 1, 581-589 | pdf | DOI
Fluoroglycoproteins: Ready Chemical Site-Selective Incorporation of Fluorosugars into Proteins
O. Boutureira, F. D'Hooge, M. Fernandez-Gonzalez, G.J.L. Bernardes, M. Sanchez-Navarro, J.R. Koeppe, B.G. Davis
Chem. Commun. 2010, 46, 8142-8144 | pdf | DOI
Lectin-directed Enzyme Activated Prodrug Therapy (LEAPT): Synthesis and Evaluation of Rhamnose-capped Prodrugs
P. Garnier, X.-T. Wang, M.A. Robinson, S. van Kasteren, A.C. Perkins, M. Frier, A.J. Fairbanks, B.G. Davis
J. Drug Target. 2010, 18, 794-802 | pdf | DOI
Inverted Regioselectivity of C-H Amination: Unexpected Oxidation at β- rather than γ-C-H
F.J. Wyszynski, A.L. Thompson, B.G. Davis
Org. Biomol. Chem. 2010, 8, 4246-4248 | pdf | DOI
Flow Chemistry Kinetic Studies Reveal Reaction Conditions for Ready Access to Unsymmetrical Trehalose Analogues
M.K. Patel, B.G. Davis
Org. Biomol. Chem. 2010, 8, 4232-4235 | pdf | DOI
Synthesis and Solution Phase Conformation of the RG1 Fragment of the Plant Polysaccharide Pectin Reveals a Modification-Modulated Assembly Mechanism
E.M. Scanlan, M.M. Mackeen, M.R. Wormald and B.G. Davis
J. Am. Chem. Soc. 2010, 132, 7238-7239 | pdf | DOI
Filled and Glycosylated Carbon Nanotubes for In Vivo Radioemitter Localization and Imaging
S.Y Hong, G. Tobias, K.T. Al-Jamal, B. Ballesteros, H. Ali-Boucetta, S. Lozano-Perez, P.D. Nellist, R.B. Sim, C. Finucane, S.J. Mather, M.L.H. Green, K. Kostarelos and B.G. Davis
Nat. Materials 2010, 9, 485-490 | pdf | DOI
This article was highlighted in Nature Chemistry and Nature Materials and was the feature of a cartoon in Phenotype (Oxford University Biochemical Society)
Safe and Scalable Preparation of Barluenga's Reagent (Bis(Pyridine)Iodonium(I) Tetrafluoroborate)
J.M. Chalker, A.L. Thompson and B.G. Davis
Org. Synth. 2010, 87, 288-298 | pdf
Synthesis and Characterization of CsI encapsulated/intercalated WS2 Inorganic Nanotubes
R. Popovitz-Biro, G. Tobias, B. Ballesteros, B.G. Davis, M.L.H. Green and R. Tenne
Nano Res. 2010, 3, 170-173 | pdf | DOI
Mechanistic Insight into Enzymatic Glycosyl Transfer with Retention of Configuration through Analysis of Glycomimetic Inhibitors
J.C. Errey, S.S. Lee, R.P. Gibson, C.M. Fleites, C.S. Barry, P.M.J. Jung, A. O'Sullivan, B.G. Davis and G.J. Davies
Angew. Chem. Intl Ed. 2010, 49, 1234-1237 | pdf | DOI
Group Epitope Mapping Considering Relaxation of the Ligand (GEM-CRL): Including Longitudinal Relaxation Rates in the Analysis of Saturation Transfer Difference (STD) Experiments
S. Kemper, M.K. Patel, J.C. Errey, B.G. Davis, J.A. Jones and T.D.W. Claridge
J. Magn. Reson. 2010, 203, 1-10 | pdf | DOI
Sweet Flexibility
B.G. Davis
Nat. Chem. 2010, 2, 85-86 | pdf | DOI
Controlled Polymer Synthesis - From Biomimicry Towards Synthetic Biology
G. Pasparakis, N. Krasnogor, L. Cronin, B.G. Davis and C. Alexander
Chem. Soc. Rev. 2010, 39, 286-300 | pdf | DOI
2009
Hydration of Sugars in The Gas Phase: Regioselectivity and Conformational Choice In N-Acetyl Glucosamine and Glucose
E.J. Cocinero, E.C. Stanca-Kaposta, M. Dethlefsen, B. Liu, D.P. Gamblin, B.G. Davis and J.P. Simons
Chem. Eur. J. 2009, 15, 13427-13434 | pdf | DOI
A Convenient Catalyst for Aqueous and Protein Suzuki-Miyaura Cross-Coupling
J.M. Chalker, C.S.C. Wood and B.G. Davis
J. Am. Chem. Soc. 2009, 131, 16346-16347 | pdf | DOI
This article was highlighted in Chemical & Engineering News (Nov 2009), by the Faculty of 1000, in ChemCatChem and in a Highlight Article on the Use of Palladium in Biology (Suzuki Biology) in ChemBioChem.
Photo-Induced, Family-Specific, Site-Selective Cleavage of TIM-barrel Proteins
N. Floyd, N.J. Oldham, C.J. Eyles, S. Taylor, D.A. Filatov, M. Brouard, B.G. Davis
J. Am. Chem. Soc. 2009, 131, 12518-12519 | pdf | DOI
Thiyl-Glycosylation of Olefinic Proteins: S-linked Glycoconjugate Synthesis
N. Floyd, B. Vijayakrishnan, J.R. Koeppe, B.G. Davis
Angew. Chem. Intl Ed. 2009, 48, 7798-7802 | pdf | DOI
Accessible Sugars as Asymmetric Olefin Epoxidation Organocatalysts: Glucosaminide Ketones in the Synthesis of Terminal Epoxides
O. Boutureira, J.F. McGouran, R.L. Stafford, D.P.G. Emmerson, B.G. Davis
Org. Biomol. Chem. 2009, 7, 4285-4288 | pdf | DOI
Potent Fluoro-Oligosaccharide Probe of Toxoplasmosis Adhesion
S.A. Allman, H.H. Jensen, B. Vijayakrishnan, J.A. Garnett, E. Leon, Y. Liu, D.C. Anthony, N.R. Sibson, T. Feizi, S. Matthews, B.G. Davis
ChemBioChem 2009, 10 2522-2529 | pdf | DOI
Saturation Transfer Difference NMR Reveals Functionally Essential Kinetic Differences for a Sugar Binding Repressor Protein
I. Perez-Victoria, S. Kemper, M.K. Patel, J. Edwards, J.C. Errey, L.F. Primavesi, M.J. Paul, T.D.W. Claridge, B.G. Davis
Chem. Commun. 2009, 5862-5864 | pdf | DOI
Detailed Insights from Microarray and Crystallographic Studies into Carbohydrate Recognition By Microneme Protein 1 (MIC1) of Toxoplasma gondii
J.A. Garnett, Y. Liu, E. Leon, S.A. Allman, N. Friedrich, S. Saouros, S. Curry, D. Soldati-Favre, B.G. Davis, T. Feizi, S. Matthews
Protein Sci. 2009, 18, 1935-1947 | pdf | DOI
The Building Blocks of Cellulose: The Intrinsic Conformational Structures of Cellobiose, Its Epimer, Lactose, and Their Singly Hydrated Complexes
E.J. Cocinero, D.P. Gamblin, B.G. Davis, J.P. Simons
J. Am. Chem. Soc. 2009, 131, 11117-11123 | pdf | DOI
Site-Selective Chemical Protein Glycosylation Protects from Autolysis and Proteolytic Degradation
D. Russell, N.J. Oldham, B.G. Davis
Carbohydr. Res. 2009, 344, 1508-1514 | pdf | DOI
Sugar Synthesis in a Protocellular Model Leads to a Cell Signalling response in Bacteria
P.M. Gardner, K. Winzer, B.G. Davis
Nat. Chem. 2009, 1, 377-383 | pdf | DOI
This article was highlighted in Nature Chemistry and in New Scientist.
Enabling Olefin Metathesis on Proteins: Chemical Methods for Installation of S-Allyl Cysteine
J.M. Chalker, Y.A. Lin, O. Boutureira, B.G. Davis
Chem. Commun. 2009, 3714-3716 | pdf | DOI
Rewritable Glycochips
L.G. Harris, W.C. Schofield, K.J. Doores, B.G. Davis, J.P. Badyal
J. Am. Chem. Soc. 2009, 131, 7755-7761 | pdf | DOI
Conformational Change and Selectivity in Explicitly Hydrated Carbohydrates
J.P. Simons, B.G. Davis, E.J. Cocinero, D.P. Gamblin, E.C. Stanca-Kaposta
Tetrahedron: Asymmetry 2009, 20, 718-722 | pdf | DOI
A Silver-Lined Anniversary of Fleet Iminosugars: 1984-2009, from DIM to DRAM to LABNAc
B.G. Davis
Tetrahedron: Asymmetry 2009, 20, 652-671 | pdf | DOI
The Linear Assembly of a Pure Glycoenzyme
B.G. Davis
Angew. Chem. Intl Ed. 2009, 48, 4674-4678 | pdf | DOI
Olefin Metathesis for Site-Selective Protein Modification
Y.A. Lin, J.M. Chalker, B.G. Davis
ChemBioChem 2009, 10, 959-969 | pdf | DOI
This article was one of the top most accessed articles in 2009.
Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology
J.M. Chalker, G.J.L. Bernardes, Y.A. Lin, B.G. Davis
Chem. Asian J. 2009, 4, 630-640 | pdf | DOI
This article was one of the top most accessed articles in 2009.
Systemic Inflammatory Response Reactivates Immune-Mediated Lesions in Rat Brain
S. Serres, D.C. Anthony, Y. Jiang, K.A. Broom, S.J. Campbell, D.J. Tyler, S.I. van Kasteren, B.G. Davis, N.R. Sibson
J. Neurosci. 2009, 29, 4820-4828 | pdf | DOI
Carbohydrate-Aromatic Interactions: A Computational and IR Spectroscopic Investigation of the Complex, Methyl alpha-L-Fucopyranoside·Toluene, Isolated in the Gas Phase
Z. Su, E.J. Cocinero, E.C. Stanca-Kaposta, B.G. Davis, J.P. Simons
Chem. Phys. Lett. 2009, 471, 17-21 | pdf | DOI
Sugars & Proteins: New Strategies in Synthetic Biology
B.G. Davis
Pure Appl. Chem. 2009, 81, 285-298 | pdf | DOI
Peptide Secondary Structures in the Gas Phase: Consensus Motif of N-linked Glycoproteins
E.J. Cocinero, E.C. Stanca-Kaposta, D.P. Gamblin, B.G. Davis and J.P. Simons
J. Am. Chem. Soc. 2009, 131, 1282-1287 | pdf | DOI
High Purity Discrete PEG Oligomer Crystals Allow Structural Insight
A.C. French, A.L. Thompson and B.G. Davis
Angew. Chem. Intl Ed. 2009, 48, 1248-1252 | pdf | DOI
Core-Shell PbI2@WS2 Nanotubes from Capillary Wetting
R. Kreizman, S.Y. Hong, J. Sloan, R. Popovitz-Biro, A. Albu-Yaron, G. Tobias, B. Ballesteros, B.G. Davis, M.L.H. Green, R. Tenne
Angew. Chem. Intl Ed. 2009, 48, 1230-1233 | pdf | DOI
Glyconanoparticles Allow Pre-symptomatic In Vivo Imaging of Brain Disease
S.I. van Kasteren, S.J. Campbell, S. Serres, D.C. Anthony, N.R. Sibson, B.G. Davis
Proc. Natl Acad. Sci. U.S.A. 2009, 106, 18-23 | pdf | DOI
This article was highlighted in PNAS and in Chemical and Engineering News.
Glycoprotein Synthesis: An Update
D.P. Gamblin, E.M. Scanlan, and B.G. Davis
Chem. Rev. 2009, 109, 131-163 | pdf | DOI
2008
Probing the Glycosidic Linkage: Secondary Structures in the Gas Phase
J.P Simons, E.C. Stanca-Kaposta, E.J. Cocinero, B. Liu, B.G. Davis, D.P Gamblin, R.T Kroemer
Phys. Scr. 2008, 89, 058124 | pdf | DOI
Conformational Choice and Selectivity in Singly and Multiply Hydrated Monosaccharides in the Gas Phase
E.J. Cocineroa, E.C. Stanca-Kaposta, D.P. Gamblin, B.G. Davis, J.P. Simons
Chem. Eur. J. 2008, 14, 8947-8955 | pdf | DOI
Glycomimetic Inhibitors of Mycobacterial Glycosyltransferases: Targeting the TB Cell Wall
R. Lucas, P. Balbuena, M. Squire, S.S. Gurcha, M. McNeil, G.S. Besra, B.G. Davis
ChemBioChem 2008, 9, 2197-2199 | pdf | DOI
Solvent Interactions and Conformational Choice in a Core N-Glycan Segment: Gas Phase Conformation of the Central, Branching Trimannose Unit and its Singly Hydrated Complex
E.C. Stanca-Kaposta, D.P. Gamblin, E.J. Cocinero, J. Frey, R.T. Kroemer, A.J. Fairbanks, B.G. Davis, J.P. Simons
J. Am. Chem. Soc. 2008, 130, 10691-10696 | pdf | DOI
Allyl Sulfides are Privileged Substrates in Aqueous Cross-Metathesis: Application to Site-Selective Protein Modification
Y.A. Lin, J.M. Chalker, N. Floyd, G.J.L. Bernardes, B.G. Davis
J. Am. Chem. Soc. 2008, 130, 9642-9643 | pdf | DOI
This article was highlighted in Chemical & Engineering News (July 2008): html,
by the Faculty of 1000, and in Nature Chemical Biology: pdf
Reagent Switchable Stereoselective β(1,2) Mannoside Mannosylation: OH-2 of Mannose is a Privileged Acceptor
K.J. Doores, B.G. Davis
Org. Biomol. Chem. 2008, 8, 2692-2696 | pdf | DOI
Chemical Site-Selective Prenylation of Proteins
D.P. Gamblin, S.I. van Kasteren, G.J.L. Bernardes, J.M. Chalker, N.J. Oldham, A.J. Fairbanks, B.G. Davis
Mol. Biosyst. 2008, 4, 558-561 | pdf | DOI
Facile Conversion of Cysteine and Alkyl Cysteines to Dehydroalanine on Protein Surfaces: Versatile and Switchable Access to Functionalized Proteins
G.J.L. Bernardes, J.M. Chalker, J.C. Errey, B.G. Davis
J. Am. Chem. Soc. 2008, 130, 5052-5053 | pdf | DOI
This article was highlighted in Chemical & Engineering News (March 2008): html
and in Nature Chemical Biology: pdf
Chemical Approaches to Mapping the Function of Post-Translational Modifications
D.P. Gamblin, S.I. van Kasteren, J.M. Chalker, B.G. Davis
FEBS J. 2008, 275, 1949-1959 | pdf | DOI
From Disulfide- to Thioether-linked Glycoproteins
G.J.L. Bernardes, E.J. Grayson, S. Thompson, J.M. Chalker, J. C. Errey, F. El Oualid, T.D.W. Claridge, B.G. Davis
Angew. Chem. Int. Ed. 2008, 47, 2244-2247 | pdf | DOI
2007
Site-Selective Glycosylation of Proteins: Creating Synthetic Glycoproteins
S.I. van Kasteren, H.B. Kramer, D.P. Gamblin, B.G. Davis
Nat. Protoc. 2007, 2, 3185-3194 | pdf | DOI
Removal of Amorphous Carbon for the Efficient Sidewall Functionalisation of Single-Walled Carbon Nanotubes
L. Shao, G. Tobias, C.G. Salzmann, B. Ballesteros, S.Y. Hong, A. Crossley, B.G. Davis, M.L.H. Green
Chem. Commun. 2007, 5090-5092 | pdf | DOI
Atomic-Scale Detection of Organic Molecules Coupled to Single-Walled Carbon Nanotubes
S.Y. Hong, G. Tobias, B. Ballesteros, F. El Oualid, J.C. Errey, K.J. Doores, A.I. Kirkland, P.D. Nellist, M.L.H. Green , B.G. Davis
J. Am. Chem. Soc. 2007, 129, 10966-10967 | pdf | DOI
Enzymatic Glycosynthesis GeTs Better
B.G. Davis
Nat. Chem. Biol. 2007, 3, 604-605 | pdf | DOI
A Trisulfide-linked Glycoprotein
G.J.L. Bernardes, J.P. Marston, A.S. Batsanov, J.A.K. Howard, B.G. Davis
Chem. Commun. 2007, 3145-3147 | pdf | DOI
Chemical and Chemoezymatic Synthesis of Glycosyl-Amino Acids and Glycopeptides Related to Trypanosoma cruzi Mucins
V.L. Campo, I. Carvalho, S. Allman, B.G. Davis, R.A. Field
Org. Biomol. Chem. 2007, 5, 2645-2657 | pdf | DOI
Carbohydrate Molecular Recognition: A Spectroscopic Investigation of Carbohydrate-Aromatic Interactions
E.C. Stanca-Kaposta, D.P. Gamblin, J. Screen, B. Liu, L.C. Snoek, B.G. Davis, J.P. Simons
Phys. Chem. Chem. Phys. 2007, 9, 4444-4451 | pdf | DOI
A Glycosynthase-Catalyst for Synthesis of Flavonoid Glycosides
M. Yang, G.J. Davies, B.G. Davis
Angew. Chem. Int. Ed. 2007, 46, 3885-3888 | pdf | DOI
IR-Spectral Signatures of Aromatic-Sugar Complexes: Probing Carbohydrate-Protein Interactions
J. Screen, E.C. Stanca-Kaposta, D.P. Gamblin, B. Liu, N.A. Macleod, L.C. Snoek, B.G. Davis, J.P.Simons
Angew. Chem. Int. Ed. 2007, 46, 3644-3648 | pdf | DOI
Expanding the Diversity of Chemical Protein Modification Allows Post-Translational Mimicry
S.I. van Kasteren, H.B. Kramer, H.H. Jensen, S.J. Campbell, J. Kirkpatrick, N.J. Oldham, D.C. Anthony, B.G. Davis
Nature 2007, 446, 1105-1109 | pdf | DOI
Folding of an MHC class II-restricted Tumor Antigen Controls its Antigenicity via MHC-guided Processing
Y. Mimura, Y. Mimura-Kimura, K.J. Doores, D. Golgher, B.G. Davis, R.A. Dwek, P.M. Rudd, T. Elliott
Proc. Natl. Acad. Sci. USA 2007, 104, 5983-5988 | pdf | DOI
The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity
D.N. Bolam, S. Roberts, M.R. Proctor, J.P. Turkenburg, E.J. Dodson, C. Martinez-Fleites, M. Yang, B.G. Davis, G.J. Davies, H.J. Gilbert
Proc. Natl. Acad. Sci. USA 2007, 104, 5336-5341 | pdf | DOI
This article was highlighted by the Faculty of 1000.
2006
The Imitation Game—A Computational Chemical Approach to Recognizing Life
L. Cronin, N. Krasnogor, B.G. Davis, C. Alexander, N. Robertson, J.H.G. Steinke, S.L.M. Schroeder, A.N. Khlobystov, G. Cooper, P.M. Gardner, P. Siepmann, B.J. Whitaker, D. Marsh
Nat. Biotech. 2006, 24, 1203-1206 | pdf | DOI
Direct Formation of Glycosyl Thiols from Reducing Sugars Allows One-pot Protein Glycoconjugation
G. Bernardes, D.P. Gamblin, B.G. Davis
Angew. Chem. Int. Ed. 2006, 45, 4007-4011 | pdf | DOI
Unique Regulation of the Active site of the Serine Esterase S-Formylglutathione Hydrolase
I. Cummins, K. McAuley, A. Fordham-Skelton, R. Schwoerer, P.G. Steel, B.G. Davis, R. Edwards
J. Mol. Biol. 2006, 359, 422-432 | pdf | DOI
The Expanding Roles of Biocatalysis and Biotransformation
G. DeSantis, B.G. Davis
Curr. Opin. Chem. Biol. 2006, 10, 139-140 | pdf | DOI
Direct Deprotected Glycosyl-Asparagine Ligation
K.J. Doores, Y. Mimura, R.A. Dwek, P.M. Rudd, T, Elliott, B.G. Davis
Chem. Commun. 2006, 1401-1403 | pdf | DOI
Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification
W. Offen, C. Martinez-Fleites, M. Yang, E. Kiat-Lim, B.G. Davis, C.A. Tarling, C.M. Ford, D.J. Bowles, G.J. Davies
EMBO J. 2006, 25, 1396-1405 | pdf | DOI
Building Up Key Segments of N-Glycans in the Gas Phase: Intrinsic Structural Preferences of the α(1,3) and α(1,6) Dimannosides
P. Çarçabal, I. Hünig, D.P. Gamblin, B. Liu, R.A. Jockusch, R.T. Kroemer, L.C. Snoek, A.J. Fairbanks, B.G. Davis, J.P. Simons
J. Am. Chem. Soc. 2006, 128, 1976-1981 | pdf | DOI
Carbohydrate-Derived Amino-Alcohol Ligands for Asymmetric Alkynylation of Aldehydes
D.P.G. Emmerson, W.P. Hems, B.G. Davis
Org. Lett. 2006, 8, 207-210 | pdf | DOI
Exploring and Exploiting the Therapeutic Potential of Glycoconjugates
K.J. Doores, D.P. Gamblin, B.G. Davis
Chem. Eur. J. 2006, 12, 656-665 | pdf | DOI
Spectral Signatures of Structural Motifs in Isolated and Hydrated Monosacharides: phenyl α- and β-L-fucopyranoside
P. Çarçabal, T. Patsias I. Hünig, B. Liu, C. Kaposta, L.C. Snoek, D.P. Gamblin, B.G. Davis, J.P. Simons
Phys. Chem. Chem. Phys. 2006, 8, 129-136 | pdf | DOI
2005
Glycosyldisulfides: Novel Glycosylating Reagents with Flexible Aglycon Alteration
E.J. Grayson, S.J. Ward, A.L. Hall, P.M. Rendle, D.P. Gamblin, A.S. Batsanov, B.G. Davis
J. Org. Chem. 2005, 70, 9740-9754 | pdf | DOI
Diversification in Substrate Usage by Glutathione Synthetases from Soya Bean (Glycine max), wheat (Triticum aestivum) and maize (Zea mays)
M. Skipsey, B.G. Davis, R. Edwards
Biochem. J. 2005, 391, 567-574 | pdf | DOI
A Carbohydrate-Antioxidant Hybrid Polymer Reduces Oxidative Damage in Spermatozoa and Enhances Fertility
C. Fleming, A. Maldjian, D. Da Costa, P. Penny, R.C. Noble, N.R. Cameron, B.G. Davis
Nat. Chem. Biol. 2005, 1, 270-274 | pdf | DOI
Ligand Amplification in a Dynamic Combinatorial Glycopeptide Library
T. Hotchkiss, H.B. Kramer, K.J. Doores, D.P. Gamblin, N.J. Oldham, B.G. Davis
Chem. Commun. 2005, 4264-4266 | pdf | DOI
Hydrogen Bonding and Cooperativity in Isolated and Hydrated Sugars: Mannose, Galactose, Glucose, and Lactose
P. Çarçabal, R.A. Jockusch, I. Hünig, L.C. Snoek, R.T. Kroemer, B.G. Davis, D.P. Gamblin, I. Compagnon, J. Oomens, J.P. Simons
J. Am. Chem. Soc. 2005, 127, 11414-11425 | pdf | DOI
Structural Dissection and High-Throughput Screening of Mannosylglycerate Synthase
J. Flint, E. Taylor, M. Yang, D.N. Bolam, L.E. Tailford, C. Martinez-Fleites, E.J. Dodson, B.G. Davis, H.J. Gilbert, G.J. Davies
Nat. Struct. Mol. Biol. 2005, 12, 608-614 | pdf | DOI
Probing the Breadth of Glycosyltransferases: In Vitro Remodeling of a Polyketide Antibiotic Creates Active Bacterial Uptake and Enhances Potency
M. Yang, M.R. Proctor, D.N. Bolam, J.C. Errey, R.A. Field, H.J. Gilbert, B.G. Davis
J. Am. Chem. Soc. 2005, 127, 9336-9337 | pdf | DOI
This article was highlighted by the Faculty of 1000.
Adding Water to Sugar: A Spectroscopic and Computational Study of α- and β-Phenylxyloside in the Gas Phase
I. Hünig, A.J. Painter, R.A. Jockusch, P. Çarçabal, E.M. Marzluff, L.C. Snoek, D.P. Gamblin, B.G. Davis, J.P. Simons
Phys. Chem. Chem. Phys. 2005, 7, 2474-2480 | pdf | DOI
A Tuneable Method for N-Debenzylation of Benzylamino Alcohols
E.J. Grayson, B.G. Davis
Org. Lett. 2005, 7, 2361-2364 | pdf | DOI
Lectins: Tools for the Molecular Understanding of the Glycocode
M. Ambrosi, N.R. Cameron, B.G. Davis
Org. Biomol. Chem. 2005, 3, 1593-1608 | pdf | DOI
Developing Promiscuous Glycosidases for Glycoside Synthesis: Residues W433 and E432 in Sulfolobus solfataricus β-Glycosidase are Important Glucoside- and Galactoside-Specificity Determinants
S.M. Hancock, K. Corbett, A.P. Fordham-Skelton, J.A. Gatehouse, B.G. Davis
ChemBioChem 2005, 6, 866-875 | pdf | DOI
Investigation of the Interaction Between Peanut Agglutinin and Synthetic Glycopolymeric Multivalent Ligands
M. Ambrosi, N.R. Cameron, B.G. Davis, S. Stolnik
Org. Biomol. Chem. 2005, 3, 1476-1480 | pdf | DOI
Glycoviruses: Chemical Glycosylation Retargets Adenoviral Gene Transfer
O.M.T. Pearce, K.D. Fisher, J. Humphries, L.W. Seymour, A. Smith, B.G. Davis
Angew. Chem. Int. Ed. 2005, 44, 1057-1061 | pdf | DOI
High-Throughput Mass-Spectroscopy Monitoring for Substrate Enzymes: Determining the Kinetic Parameters and Catalytic Activities of Glycosyltransferases
M. Yang, M. Brazier, R. Edwards, B.G. Davis
ChemBioChem 2005, 6, 346-357 | pdf | DOI
Glyco- and Peptidomimetics from Three-Component Jouillé-Ugi Coupling Show Selective Antiviral Activity
T.M. Chapman, I.G. Davies, B. Gu, T.M. Block, D.I.C. Scopes, P.A. Hay, S.M. Courtney, L.A. McNeill, C.J. Schofield, B.G. Davis
J. Am. Chem. Soc. 2005, 127, 506-507 | pdf | DOI
"Polar Patch" Proteases as Glycopeptiligases
K.J. Doores, B.G. Davis
Chem. Commun. 2005, 168-170 | pdf | DOI
Carbohydrate-derived Aminoalcohol Ligands for Asymmetric Reformatsky Reactions
D.P.G. Emmerson, W.P. Hems, B.G. Davis
Tetrahedron: Asymmetry 2005, 16, 213-222 | pdf | DOI
This article was in the top 25 downloaded from Tetrahedron: Asymmetry in 2005.
2004
LEAPT: Lectin-directed Enzyme Activated Prodrug Therapy
M.A. Robinson, S.T. Charlton, P. Garnier, X. Wang, S.S. Davis, A.C. Perkins, M. Frier, R. Duncan, T.J. Savage, D.A. Wyatt, S.A. Watson, B.G. Davis
Proc. Natl. Acad. Sci. USA 2004, 101, 14527-14532 | pdf | DOI
This article is featured in Nature Reviews Drug Discovery (November 2004): html, pdf
Selective Electrochemical Glycosylation by Reactivity Tuning
R.R. France, R.G. Compton, B.G. Davis, A.J. Fairbanks, N.V. Rees, J.D. Wadhawan
Org. Biomol. Chem. 2004, 2, 2195-2002 | pdf | DOI
Plasmachemical Surface Functionalised Beads: Versatile Tailored Supports for Polymer Assisted Organic Synthesis
J.P. Badyal, A.M. Cameron, N.R. Cameron, D.M. Coe, R. Cox, B.G. Davis, L. J. Oates, G. Øye, C. Spanos, P.G. Steel
Chem. Commun. 2004, 1402-1403 | pdf | DOI
Modular Control of Lectin Function: Redox-Switchable Agglutination
R.E. McDonald, D.J. Hughes, B.G. Davis
Angew. Chem. Int. Ed. 2004, 43, 3025-3029 | pdf | DOI
Glycodendriproteins: a Synthetic Glycoprotein Mimic Enzyme with Branched Sugar-display Potently Inhibits Bacterial Aggregation
P.M. Rendle, A. P. Seger, J. Rodrigues, N.J. Oldham, R.R. Bott, J.B. Jones, M.M. Cowan, B.G. Davis
J. Am. Chem. Soc. 2004, 126, 4750-4751 | pdf | DOI
This article was featured in Nature (29 April 2004): html | pdf
and in the Financial Times: pdf
Comparison of the Effect of Pore Architecture and Bead Size on the Extent of Plasmachemical Amine Functionalisation of Poly(styrene-co-divinylbenzene) Permanently Porous Resins
J.P. Badyal, A.M. Cameron, N.R. Cameron, L.J. Oates, G. Øye, P.G. Steel, B.G. Davis, D.M. Coe, R.A. Cox
Polymer 2004, 45, 2185-2192 | pdf | DOI
Mimicking Posttranslational Modifications of Proteins
B.G. Davis
Science 2004, 303, 480-482 | pdf | DOI
Glyco-SeS: Selenenylsulfide-Mediated Protein Glycoconjugation - A New Stategy in Posttranslational Modification
D.P. Gamblin, P. Garnier, S. van Kasteren, N.J. Oldham, A.J. Fairbanks, B.G. Davis
Angew. Chem. Int. Ed. 2004, 43, 828-833 | pdf | DOI
2003
Synthetic Methods: Part (III) Enzyme Methods
B.G. Davis
Annu. Rep. Prog. Chem. Sect. B 2003, 98, 49-62 | pdf
Precise Structure Activity Relationships in Asymmetric Catalysis Using Carbohydrate-Scaffolds to Allow Ready Fine Tuning: Dialkylzinc-Aldehyde Additions
D.P.G. Emmerson, R. Villard, C. Mugnaini, A. Batsanov, J.A.K. Howard, W.P. Hems, R.P. Tooze, B.G. Davis
Org. Biomol. Chem. 2003, 1, 3826-3838 | pdf | DOI
Glycosyl Phenylthiosulfonates (Glyco-PTS): Novel Reagents for Glycoprotein Synthesis
D.P. Gamblin, P. Garnier, S.J. Ward, N.J. Oldham, A.J. Fairbanks, B.G. Davis
Org. Biomol. Chem. 2003, 1, 3642-3644 | pdf | DOI
Nitrogen Inversion as a Diastereomeric Relay in Azasugar Synthesis: the First Synthesis of Adenophorine
M.A.T. Maughan, I.G. Davies, T.D.W. Claridge, S. Courtney, P. Hay, B.G. Davis
Angew. Chem. Int. Ed. 2003, 42, 3788-3792 | pdf | DOI
Chemical Modification of Biocatalysts
B.G. Davis
Curr. Opin. Biotechnol. 2003, 14, 379-386 | pdf | DOI
Highly Diastereoselective Additions to Polyhydroxylated Pyrrolidine Cyclic Imines: Ready Elaboration of Aza-Sugar Scaffolds to Create Diverse Carbohydrate-Processing Enzyme Probes
T.M. Chapman, S. Courtney, P. Hay, B.G. Davis
Chem. Eur. J. 2003, 9, 3397-3414 | pdf | DOI
Selective Protein Degradation by Ligand-Targeted Enzymes: Towards the Creation of Catalytic Antagonists
B.G. Davis, R.F. Sala, D.R.W. Hodgson, A. Ullman, K. Khumtaveeporn, D.A. Estell, K. Sanford, R.R. Bott, J.B. Jones
ChemBioChem 2003, 4, 533-537 | pdf | DOI
Solid Phase Peptide Templated Glycosidic Bond Formation
R.J. Tennant-Eyles, B.G. Davis, A.J. Fairbanks
Tetrahedron: Asymmetry 2003, 14, 1201-1210 | pdf | DOI
Plasmachemical Amine Functionalization of Porous Polystyrene Spheres: The Importance of Particle Size
G. Øye, V. Roucoules, L.J. Oates, A.M. Cameron, N.R. Cameron, P.G. Steel, J.P.S. Badyal, B.G. Davis, D.M. Coe, R.A. Cox
J. Phys. Chem. B 2003, 107, 3496-3499 | pdf | DOI
2002
Synthetic Methods: Part (V) Enzyme Methods
B.G. Davis
Annu. Rep. Prog. Chem. Sect. B 2002, 98, 91-122
Plasmachemical Amine Functionalization of Porous Polystyrene Beads: The Importance of Pore Architecture
G. Øye, V. Roucoules, A. M. Cameron, L. J. Oates, N. R. Cameron, P. G. Steel, J. P. S. Badyal, B. G. Davis, D. Coe, R. Cox
Langmuir 2002, 18, 8996-8999 | pdf | DOI
Chemically Modified "Polar Patch" Mutants of Subtilisin in Peptide Synthesis with Remarkably Broad Substrate Acceptance: Designing Combinatorial Biocatalysts
K. Matsumoto, B.G. Davis, J.B. Jones
Chem. Eur. J. 2002, 8, 4129-4137 | pdf | DOI
Functional Divergence in the Glutathione Transferase Super-Family in Plants: Identification of Two Classes with Putative Functions in Redox Homeostasis in Arabidopsis Thaliana
D.P. Dixon, B.G. Davis, R. Edwards
J. Biol. Chem. 2002, 277, 30859-30869 | pdf | DOI
Towards an Unprotected Self-Activating Glycosyl Donor System: Bromobutyl Glycosides
B.G. Davis, S.D. Wood, M.A.T. Maughan
Can. J. Chem. 2002, 80, 555-558 | pdf
Drug Delivery Systems Based on Sugar-Macromolecule Conjugates
B.G. Davis, M.A. Robinson
Curr. Opin. Drug Discovery Develop. 2002, 5, 279-288 | pdf
Synthesis of Glycoproteins
B.G. Davis
Chem. Rev. 2002, 102, 579-601 | pdf | DOI
Novel Cyclic Sugar Imines: Carbohydrate Mimics and Easily Elaborated Scaffolds for Aza-Sugars
B.G. Davis, M.A.T. Maughan, T.M. Chapman, R. Villard, S. Courtney
Org. Lett. 2002, 4, 103-106 | pdf | DOI
Influence of Preparation Procedure on Polymer Composition: Synthesis and Characterisation of Polymethacrylates Bearing β-D-Glucopyranoside and β-D-Galactopyranoside Residues
M. Ambrosi, A.S. Batsanov, N.R. Cameron, B.G. Davis, J.A.K. Howard, R. Hunter
J. Chem. Soc., Perkin Trans. 1 2002, 45-52 | pdf | DOI
2001
Tailoring the Substrate Specificity of the β-Glycosidase from the Thermophilic Archeon Sulfolobus solfataricus
K. Corbett, A.P. Fordham-Skelton, J.A. Gatehouse, B.G. Davis
FEBS Lett. 2001, 509, 355-360 | pdf | DOI
Biocatalysis and Enzymes in Organic Synthesis
V. Boyer, B.G. Davis
Natural Prod. Rep. 2001, 18, 618-640 | pdf | DOI
A Simple Method for the Quantitative Analysis of Resin Bound Thiol Groups
J.P. Badyal, A.M. Cameron, N.R. Cameron, D.M. Coe, R. Cox, B.G. Davis, L.J. Oates, G. Oye, P.G. Steel
Tetrahedron Lett. 2001, 42, 8531-8533 | pdf | DOI
Ready Protease-Catalyzed Synthesis of Carbohydrate-Peptide Conjugates
V. Boyer, M. Stanchev, A.J. Fairbanks, B.G. Davis
Chem. Commun. 2001, 1908-1910 | pdf | DOI
Glycosylation of the Primary Binding Pocket of a Subtilisin Protease Causes a Remarkable Broadening in Stereospecificity in Peptide Synthesis
K. Matsumoto, B.G. Davis, J.B. Jones
Chem. Commun. 2001, 903-904 | pdf | DOI
Expanding the Utility of Proteases in Synthesis: Broadening the Substrate Acceptance in Non-Coded Amide Bond Formation Using Chemically Modified Mutants of Subtilisin
K. Khumatveeporn, A. Ullman, K. Matsumoto, B.G. Davis, J.B. Jones
Tetrahedron: Asymmetry 2001, 12, 249-261 | pdf | DOI
The Controlled Glycosylation of a Protein with a Bivalent Glycan: Towards a New Class of Glycoconjugates, Glycodendriproteins
B.G. Davis
Chem. Commun. 2001, 351-352 | pdf | DOI
Glycosyldisulfides: a New Class of Solution and Solid Phase Glycosyl Donors
B.G. Davis, S.J. Ward and P.M. Rendle
Chem. Commun. 2001, 189-190 | pdf | DOI
2000
Site-Selective Glycosylation of Subtilisin Bacillus lentus Causes Dramatic Increases in Esterase Activity
R.C. Lloyd, B.G. Davis, J.B. Jones
Bioorg. Med. Chem. 2000, 8, 1537-1544 | pdf | DOI
Controlled Site-Selective Protein Glycosylation for Precise Glycan Structure-Catalytic Activity Relationships
B.G. Davis, R.C. Lloyd, J.B. Jones
Bioorg. Med. Chem. 2000, 8, 1527-1535 | pdf | DOI
Recent Developments in Oligosaccharide Synthesis
B.G. Davis
J. Chem. Soc., Perkin Trans. 1 2000, 2137-2160 | pdf | DOI
Hand in Glove - Investigating Glycocode
B.G. Davis
Chem. Ind. 2000, 134-138 | pdf
Glycomethanethiosulfonates: Powerful Reagents for Protein Glycosylation
B.G. Davis, M.A.T. Maughan, M.P. Green, A. Ullman, J.B. Jones
Tetrahedron: Asymmetry 2000, 11, 245-262 | pdf | DOI
Peptide Templated Glycosylation Reactions
R.J. Tennant-Eyles, B.G. Davis, A.J. Fairbanks
Tetrahedron: Asymmetry 2000, 11, 231-244 | pdf | DOI
1999
Recent Developments in Glycoconjugates
B.G. Davis
J. Chem. Soc., Perkin Trans. 1 1999, 3215-3237 | pdf | DOI
Altering the Specificity of subtilisin Bacillus lentus Through the Introduction of Positive Charge at Single Amino Acid Sites
B.G. Davis, K. Khumtaveepron, R.R. Bott, J.B. Jones
Bioorg. Med. Chem. 1999, 7, 2303-2312 | pdf | DOI
The Controlled Introduction of Multiple Negative Charge at Single Amino Acid Sites in Subtilisin Bacillus lentus
B.G. Davis, X. Shang, G. DeSantis, R.R. Bott, J. B. Jones
Bioorg. Med. Chem. 1999, 7, 2293-2302 | pdf | DOI
Glycoprotein Synthesis: From Glycobiological Tools to Tailor-made Catalysts
B.G. Davis, J.B. Jones
SynLett 1999, 1495-1507 | pdf | DOI
Peptide Templated Glycosidic Bond Formation: a New Strategy for Oligosaccharide Synthesis
R.J. Tennant-Eyles, B.G. Davis, A.J. Fairbanks
Chem. Commun. 1999, 1037-1038 | pdf | DOI
Tetrazoles of Manno- and Rhamno- Furanoses
B.G. Davis, R.J. Nash, A.A. Watson, C. Smith, G.W.J. Fleet
Tetrahedron 1999 55, 4501-4520 | pdf | DOI
Tetrazoles of Manno- and Rhamno- Pyranoses: Contrasting Inhibition of Mannosidases by [4.3.0] but of Rhamnosidase by [3.3.0] Bicyclic Tetrazoles
B.G. Davis, T.W. Brandstetter, L. Hackett, B.G. Winchester, R.J. Nash, AA. Watson, R.C. Griffiths, C. Smith, G.W.J. Fleet
Tetrahedron 1999, 55, 4489-4500 | pdf | DOI
1998
Controlled Site-Selective Glycosylation of Proteins by a Combined Site-Directed Mutagenesis and Chemical Modification Approach
B.G. Davis, R.C. Lloyd, J.B. Jones
J. Org. Chem. 1998, 63, 9614-9615 | pdf | DOI
5-epi-Deoxyrhamnojirimycin is a Potent Inhibitor of an α-L-Rhamnosidase: 5-epi-Deoxymannojirimycin is Not a Potent Inhibitor of an α-D-Mannosidase
B.G. Davis, A. Hull, C. Smith, R.J. Nash, A.A. Watson, D.A. Winkler, R.C. Griffiths, G.W.J. Fleet
Tetrahedron: Asymmetry 1998, 9, 2947-2960 | pdf | DOI
1997
Caesium Trifluoroacetate Displacement of Triflates in the Inversion of Alcohols
A.A. Bell, L. Pickering, M. Finn, C. de la Fuente, T.M. Krülle, B.G. Davis, G.W.J. Fleet
SynLett 1997, 1077-1078 | DOI
1996
Inhibition of Naringinase (L-Rhamnosidase) by Piperidine Analogues of L-Rhamnose - Scaffolds for Libraries Incorporating Trihydroxypipecolic Acids
J.P. Shilvock, J.R. Wheatley, B. Davis, R.J. Nash, R.C. Griffiths, M.G.  Jones, M. Muller, S. Crook, D.J. Watkin, C. Smith, G.S. Besra, P.J. Brennan, G.W.J Fleet
Tetrahedron Lett. 1996, 37, 8569-8572 | DOI
L-(+)-Swainsonine and Other Pyrrolidine Inhibitors of Naringinase - Through an Enzymatic Looking-Glass from D-Mannosidase To L-Rhamnosidase
B. Davis, A.A. Bell, R.J. Nash, A.A. Watson, R.C. Griffiths, M.G. Jones, C. Smith, G.W.J. Fleet
Tetrahedron Lett. 1996, 37, 8565-8568 | DOI
Kinetic and Thermodynamic Azides from α-O-Triflates of γ-Lactones: Intermediates for the Incorporation of Polyhydroxylated D- and L-α-Aminoacids into Combinatorial Libraries
T.M. Krülle, B. Davis, H. Ardron, D.D. Long, N.A. Hindle, C. Smith, D. Brown, A.L. Lane, D.J. Watkin, D. Marquess, G.W.J. Fleet
J. Chem. Soc., Chem. Commun. 1996, 1271-1272 | DOI
1995
2
Tetrazoles of Manno- and Rhamno- Pyranoses: Inhibition of Glycosidases by Tetrazoles and other Mannose Mimics
T.W. Brandstetter, B. Davis, D. Hyett, C. Smith, L. Hackett, B.G. Winchester, G.W.J. Fleet
Tetrahedron Lett. 1995, 36, 7511-7514 | DOI
Tetrazoles of Manno- and Rhamno- Furanoses
B. Davis, T.W. Brandstetter, C. Smith, L. Hackett, B.G. Winchester, G.W.J. Fleet
Tetrahedron Lett. 1995, 36, 7507-7510 | DOI


Non-Peer Reviewed
Is Nurturing the Research Environment an Alternative Perspective?

B. G. Davis
Science in Parliament 2012, 69, 22-24 | pdf


Last updated: 09-09-14

NatChem 2013
ChemCommun 2013
ChemSci 2011
ChemCommun2010
JACS2010
CarbRes2010
Angew 2009
Nature Protocol 2007
Angewandte 2007
Chem Eur J, issue 3, 2006
Angewandte Chemie, issue 7, 2005

Prof Ben G. Davis
University of Oxford
Chemistry Research Laboratory
Mansfield Road
Oxford, OX1 3TA, UK
Phone: + 44 (0)1865 275652
Fax: + 44 (0)1865 275674
Ben.Davis@chem.ox.ac.uk