Pacific Islands RHD Genetics Network: Elemental Dataset

This page provides access to an elemental dataset sufficient to reproduce the key finding in our submitted manuscript: Parks et al. 2016 A common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania.

Downloads

Name File Description
Ancestries and phenotypes Ancestries_and_phenotypes.zip Text files intended for use in PLINK or GCTA coded 1 for unaffected and 2 for affected.
Kinship patrices Kinship_matrices.zip Kinship matrices for each ancestry in GCTA format for use in linear mixed model analyses.
GWAS format genotypes GWAS_format.zip Imputed genotype probabilities in GWAS format (aka Oxford format) for use in various programmes.
MACH format genotypes MACH_format.zip Imputed genotype probabilities in MACH format for use in GCTA.