University of Oxford
Home     Research     Publications     The Group     Opportunities     News     Teaching     Contact
 
 
Publications
 
         
  Books  
         
    Oxidation and Reduction in Organic Synthesis: OUP Chemistry Primer No. 6  
     
Primer No. 6
 
    Timothy J. Donohoe
 
    Oxford University Press, 2000, ISBN 0198556640.  
       
       
       
  Independent Publications  
       
  113 Ruthenium catalysed isomerization of terminal Olefins: applications to synthesis  
    Timothy J. Donohoe, Timothy J.C. O'Riordan and Carla P. Rosa  
    Angew. Chem. Int. Ed., 2008, in the press [link to journal]  
       
  112 Quantitative voltammetry of the reduction of methyl benzoate in THF reveals strong ion pairing of the radical anion with tetra-n-butyl cations  
    Ronan Baron, Neil M. Kershaw, Timothy J. Donohoe and Richard G. Compton  
    Journal of Phys. Org. Chem., 2008, in the press [link to journal]  
       
  111 Synthesis of (+)-DGDP and (-)-7-Epialexine  
    Timothy J. Donohoe, Matthew D. Cheeseman, Timothy J.C. O'Riordan and Jessica A. Kershaw  
    Organic and Biomolecular Chemistry, 2008, 6(21), 3896-3898 [link to journal]  
       
  110 Alkali metal reductions of organic molecules: why mediated electron transfer from Lithium is faster than direct reduction  
    Neil Rees, Ronan Baron, Neil Kershaw, Timothy J. Donohoe, Richard J. Compton  
    J. Am. Chem. Soc., 2008, 130, 12256-12257 [link to journal]  
       
  109 Hydrogen bonding mediated directed Osmium dihydroxylation  
    Timothy J. Donohoe, Carole J.R. Bataille and Paolo Innocenti  
    Organic Reactions, 2008, in the press [link to journal]  
       
  108 A flexible strategy for the synthesis of pyrrolizidine alkaloids  
    Timothy J. Donohoe, Rhian Thomas, Matthew Cheeseman, Caroline Rigby, Ian Linney and Gurdip Bhalay  
    Organic Letters, 2008, 10, 3615-3618 [link to journal]  
       
  107 Synthesis of (­–)-(/Z/)-deoxypukalide: application of ring closing metathesis to the construction of complex aromatic heterocyclic natural products  
    Timothy J. Donohoe, Alan Ironmonger and Neil M. Kershaw  
    Angew. Chem. Int. Ed., 2008, 47, 7314-7316 [link to journal]  
       
  106 Ring-closing metathesis as a key step in the synthesis of 2-pyridones and pyridine triflates  
    Timothy J. Donohoe, Lisa P. Fishlock and Panayiotis A. Procopiou  
    Synthesis, 2008, 129, 2665-2667 (Practical Synthetic Procedure) [link to journal]  
       
  105 Ring-closing metathesis: novel routes to aromatic heterocycles  
    Timothy J. Donohoe, Lisa P. Fishlock and Pan A. Procopiou  
    Chemistry: A European Journal, 2008, 14, 5716-5726 [link to journal]  
       
  104 Pyridine-N-Oxide as a mild reoxidant which transforms Osmium catalysed oxidative cyclisation  
    Timothy J. Donohoe, Katherine M.P. Wheelhouse (née) Gosby, Peter J. Lindsay-Scott, Paul A. Glossop, Ian A. Nash and Jeremy S. Parker  
    Angew. Chem. Int. Ed., 2008, 47, 2872 [link to journal]  
       
  103 Hydride shift generated oxonium ions: evidence for mechanism and intramolecular trapping experiments to form trans THFs  
    Timothy J. Donohoe, Oliver Williams and Gwydion H. Churchill  
    Angew. Chem. Int. Ed., 2008, 47, 2869 [link to journal]  
       
  102 A metathesis-based approach to the synthesis of 2-Pyridones and Pyridines  
    Timothy J. Donohoe, Lisa P. Fishlock and Pan A. Procopiou  
    Organic Letters, 2008, 10, 285-288 [link to journal]  
       
  101 Flexible metathesis-based approaches to highly functionalised furans and pyrroles
 
    Timothy J. Donohoe*, Neil M. Kershaw, Allan J. Orr, Katherine M. P. Wheelhouse (née Gosby), Lisa P. Fishlock, Adam R. Lacy, Matilda Bingham and Panayiotis A. Procopiou  
    Tetrahedron, 2008, 64, 809-820 [link to journal]  
       
  100 Electrosynthetic reduction of 1-iodoadamantane forming 1,1'-biadamantane and adamantane in aprotic solvents: Insonation switches the mechanism from dimerisation to exclusive monomer formation  
    Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton  
    Ultrasonics Sonochemistry, 2007, 14(5), 502-508 [link to journal]  
       
  99 Cryoelectrochemical reduction of a phenyl sulfide in tetrahydrofuran: mediated reduction gives different products compared to direct reduction  
    Alexander V. Burasov, Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton  
    J. Phys. Org. Chem., 2007, 20(2), 144-150 [link to journal]  
       
  98 Electrocatalytic reduction of alkyl iodides in tetrahydrofuran at silver electrodes  
    Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton  
    J. Phys. Org. Chem., 2007, 20(2), 115-121 [link to journal]  
       
  97 Kinetics and thermodynamics of the Li/Li+ couple in tetrahydrofuran at low temperatures (195-295 K)  
    Christoper A. Paddon, Sarah E. Ward Jones, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton  
    J. Phys. Org. Chem., 2007, 20, 677-684 [link to journal]  
       
  96 A concise and efficient synthesis of (-)-Allosamizoline  
    Timothy J. Donohoe and Carla P. Rosa  
    Organic Letters, 2007, 9, 5509-5511 [link to journal]  
       
  95 Mediated electron transfer from lithium investigated voltammetrically in tetrahydrofuran: why are some mediators more effective reducing reagents than others?  
    Natasha C.L. Wood, Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton  
    J. Phys. Org. Chem., 2007, 20, 732-742 [link to journal]  
       
  94 The partial reduction of electron-deficient pyrroles: procedures describing both
Birch (Li/NH3) and ammonia-free (Li/DBB) conditions
 
    Timothy J. Donohoe*, Rhian E. Thomas  
    Nature: Protocols, 2007, 2, 1888-1895 (plus cover picture for this issue) [link to journal]  
       
  93 The Tethered Aminohydroxylation: Dramatic Improvements to the Process  
    Timothy J. Donohoe*, Carole J. R. Bataille, William Gattrell, Johannes Kloesges and Emilie Rossignol  
    Organic Letters, 2007, 9, 1725-1728 [link to journal]  
       
  92 A Metathesis Based Approach to the Synthesis of Furans  
    Timothy J. Donohoe*, Lisa P. Fishlock, Adam R. Lacy, and Panayiotis A. Procopiou  
    Organic Letters, 2007, 9, 953-956 [link to journal]  
       
  91 Coulometry on the Voltammetric Timescale: Microdisk Potential-Step Chronoamperometry in Aprotic  
    Solvents Reliably Measures the Number of Electrons Transferred in an Electrode Process  
    Simultaneously with the Diffusion Coefficients of the Electroactive species  
    Christopher A. Paddon, Debbie S. Silvester, Farrah L. Bhatti, Timothy J. Donohoe, Richard G. Compton  
    Electroanalysis 2007, 19, 11-22. [link to journal]  
       
  90 Partial Reduction of Pyrroles: Application to Natural Product Synthesis  
    Timothy J. Donohoe*, and Rhian E. Thomas  
    The Chemical Record, 2007, 7, 180-190. [link to journal]  
   

 

 
  89 Synthesis of the Pyrrolidinone Core of KSM-2690 B  
    Timothy J. Donohoe,* Jessica Chiu, Rhian E Thomas  
    Organic Letters 2007, 9, 421-424. [link to journal]  
 
 
   
 
88
Total Synthesis of cis-Sylvaticin: Double Oxidative Cyclisation Reactions Catalysed by Osmium  
 
 
Timothy J. Donohoe,* Robert M. Harris, Jeremy Burrows and Jeremy Parker  
 
 
J. Am. Chem. Soc. 2006, 128, 13704-13705. [link to journal]  
 
 
   
 
87
Stereoselective Synthesis of Pyrrolidines: Catalytic Oxidative Cyclisations Mediated by Osmium  
 
 
Timothy J. Donohoe,* Gwydion H. Churchill, Katherine M. P. Wheelhouse (née Gosby) and Paul A. Glossop  
 
 
Angewandte Chemie Int Ed. Engl. 2006, 45, 8025-8028. [link to journal]  
 
 
   
 
86
Cryo-electrochemistry in tetrahydrofuran: The regioselective electrochemical reduction of a phenyl sulfone: Fast-scan cyclic voltammetry investigations  
 
 
Nicole Fietkaua, Christopher A. Paddon, Farrah L. Bhattib, Timothy J. Donohoe* and Richard G. Compton*  
 
 
Journal of Electroanalytical Chemistry, 2006, 593, 131-141. [link to journal]  
 
 
   
 
85
Cryovoltammetrically probing functional group reductive cleavage: Alkyl-sulfur versus aryl-sulfur bond cleavage in an alkyl naphthyl thioether under single electron transfer is temperature switchable  
 
 
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe* and Richard G. Compton*  
 
 
Chemical Communications, 2006, 3402-2404. [link to journal]  
 
 
   
 
84 
Highlights of Natural Product Synthesis  
 
 
Timothy J. Donohoe,* Carole J. R. Bataille and Gwydion H. Churchill,  
 
 
Annual Rep. Prog. Chem. Sect. B, 2006, 102, 98-122. [link to journal]  
 
 
   
 
83
An Enzymatic Approach to the Desymmetrisation of Disubstituted Pyrrolines  
 
 
Timothy J. Donohoe,* Caroline L. Rigby, Rhian E. Thomas, William F. Nieuwenhuys, Farrah L. Bhatti, Andrew R. Cowley, Gurdip Bhalay and Ian D. Linney  
 
 
Journal of Organic Chemistry, 2006, 71, 6298-6301. [link to journal]  
 
 
   
 
82
Cryo-electrochemistry in tetrahydrofuran: The electrochemical reduction of a phenyl thioether: [(3-{[ trans -4-(Methoxymethoxy)cyclohexyl]oxy}propyl)thio]benzene  
 
 
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe* and Richard G. Compton*  
 
 
Journal of Electroanalytical Chemistry, 2006, 589, 187-194. [link to journal]  
 
 
   
 
81
A New Osmium-Based Reagent for the Dihydroxylation of Alkenes  
 
 
Timothy J. Donohoe,* Robert M. Harris, Sam Butterworth, Jeremy N. Burrows, Andrew Cowley, and Jeremy S. Parker  
 
 
Journal of Organic Chemistry, 2006, 71, 4481-4489. [link to journal]  
 
 
   
 
80
 N-Sulfonyloxy Carbamates as Re-oxidants for the Tethered Aminohydroxylation (TA) Reaction  
 
 
 Timothy J. Donohoe,* Majid J. Chughtai, David J. Klauber, David Griffin and Andrew D. Campbell  
 
 
 J. Am. Chem. Soc. 2006, 128, 2514-2515. [link to journal]  
 
 
   
 
79
The Ammonia-Free Partial Reduction of Substituted Pyridinium Salts  
 
 
Timothy J. Donohoe,* Dale J. Johnson, Laura H. Mace, Rhian E. Thomas, Jessica Y. K. Chiu, Jason S. Rodrigues, Richard G. Compton, Craig E. Banks, Peter Tomcik, Mark J. Bamford and Osamu Ichihara  
 
 
Organic and Biomolecular Chemistry, 2006, 4, 1071-1084. [link to journal]  
 
 
   
 
78
Ring Closing Metathesis as a Basis for the Construction of Aromatic Compounds  
 
 
Timothy J. Donohoe,* Allan J. Orr and Matilda Bingham  
 
 
Angewandte Chemie Int Ed. Engl. 2006, 45, 2664-2670. [link to journal]  
 
 
   
 
77
A non-carbohydrate based approach to polyhydroxylated pyrrolidizines; total syntheses of the natural products hyacinthacine A1 and 1-epiaustraline  
 
 
Timothy J. Donohoe*, Herman O. Sintim and Jackie Hollinshead  
 
 
Journal of Organic Chemistry, 2005, 70, 7297-7304. [link to journal]  
 
 
   
 
76
Oxidative cyclisations of diols derived from 1,5-dienes: formation of enantiopure cis-tetrahydrofurans using catalytic osmium tetroxide and a formal synthesis of (+)-cis-solamin  
 
 
 Timothy J. Donohoe* and Sam Butterworth  
 
 
 Angewandte Chemie Int Ed. Engl. 2005, 44, 4766-4768. [link to journal]  
 
 
   
 
75
A Metathesis Approach to Aromatic Heterocycles  
 
 
Timothy J. Donohoe,* Allan J. Orr, Katherine Gosby and Matilda Bingham  
 
 
European Journal of Organic Chemistry, 2005, 1969-1971. [link to journal]  
 
 
   
 
74
A Concise and Enantioselective Synthesis of the Aminocyclitol Core of Hygromycin A  
 
 
Timothy J. Donohoe,* Peter D. Johnson, Richard J. Pye and Martine Keenan  
 
 
 Organic Letters, 2005, 7, 1275-1277. [link to journal]  
 
 
   
 
73

Utility of the ammonia-free Birch reduction of electron-deficient pyrroles: total synthesis of the 20S proteasome inhibitor, clasto-lactacystin beta-lactone

 
 
 
Timothy J. Donohoe,* Herman O. Sintim, Leena Sisangia, Karl W. Ace, Paul M. Guyo, Andrew Cowley and John D. Harling  
 
 
 Chemistry: A European Journal, 2005, 11, 4227-4238. [link to journal]  
 
 
   
 
72
Partial Reduction of Pyridinium Salts as a Versatile Route to Dihydropyridones  
 
 
Timothy J. Donohoe,* D. Johnson, L. H. Mace, O. Ichihara and M. Bamford  
 
 
Organic Letters, 2005, 7, 453-437. [link to journal]  
 
 
   
 
71
 
Cryoelectrochemistry: Electrochemical reduction of 2(RS)-Methyl 1-(tert-butoxycarbonyl)-2-iodomethyl-2,5-dihydropyrrole-2-carboxylate  
 
 
Craig E. Banks, Russell G. Evans, Jason Rodrigues, Peter G. Turner, Timothy J. Donohoe* and Richard G. Compton,*  
 
 
Tetrahedron, 2005, 61, 2365-2372 [link to journal]  
 
 
   
 
70 
Enantioselective Partial Reduction of 2,5-Disubstituted Pyrroles via a Chiral Protonation Approach  
 
 
Timothy J. Donohoe,* Catherine E. Headley, Caroline L. Rigby, Graeme C. Freestone, Rick P. C. Cousins and Gurdip Bhlay  
 
 
Organic Letters, 2004, 6, 3055-3058. [link to journal]  
 
 
   
 
69 
Efficient Acyclic Stereocontrol Using the Tethered Aminohydroxylation (TA) Reaction  
 
 
Timothy J. Donohoe,* Peter D. Johnson, Martine Keenan and Richard J. Pye  
 
 
Organic Letters, 2004, 6, 2583-2585. [link to journal]  
 
 
   
 
68 
An Efficient Synthesis of (±)-1 Epiaustraline  
 
 
Timothy J. Donohoe* and Herman O. Sintim,  
 
 
Organic Letters, 2004, 6, 2003-2006. [link to journal]  
 
 
   
 
67 
Rearrangement of Pyrrolines Derived from the Birch Reduction of Electron-Deficient Pyrroles: Radical Ring-Expansion to Substituted Tetrahydropyridines  
 
 
Timothy J. Donohoe,* Rick P. C. Cousins and Peter Turner  
 
 
Chemical Communications, 2004, 1422-1423. [link to journal]  
 
 
   
 
66
Low Temperature Electrochemistry as a Mechanistic Probe for the Partial Reduction of Heterocycles  
 
 
Timothy J. Donohoe,* Richard Compton,* Dale Johnson and Jay D. Wadhawan  
 
 
Tetrahedron, 2004, 60, 5945-5952. [link to journal]  
       
  65
An Efficient Synthesis of Lactacysin ß-Lactone  
 
Timothy J. Donohoe,* Leena Sisangia, Herman O. Sintim and John D. Harling  
 
Angewandte Chemie Int Ed. Engl. 2004, 43, 2293-2296. [link to journal]  
 
   
 
64
Enantiopure Oxazolidinones as Chiral Acids in the Asymmetric Protonation of N-Boc Pyrrole Derived Enolates  
 
Timothy J. Donohoe* and David Carbery  
 
Chemical Communications, 2004, 722-723. [link to journal]  
 
   
 
63
Synthesis of (±)-Secosyrin 1 and a Formal Synthesis of (-)-Secosyrin 1  
 
Timothy J. Donohoe,* John W. Fisher and Paul J. Edwards  
 
Organic Letters, 2004, 6, 465-467. [link to journal]  
 
   
 
62
Trichloro-oxazolines as activated donors for aminosugar coupling  
 
Timothy J. Donohoe,* James G. Logan and David D. P. Laffan  
 
Organic Letters, 2003, 5, 4995 - 4998. [link to journal]  
 
   
 
61
CCK secretion in STC-1 cells induced by analogues of dodecanoic acid: evidence that a specific fatty acid receptor is not involved  
 
S. Kazmi, R. S. P. Benson, T. J. Donohoe, M. N. Jones, M. Wickham, D. G. Thompson, R. M. Case  
 
Journal of Physiology, 2003, 553, 759-773. [link to journal]  
 
   
 
60
Osmium Tetroxide  
 
Timothy J. Donohoe, Robert Harris and Majid Chugtai  
 
Encyclopedia of Reagents for Organic Synthesis, 2003.  
 
   
 
59
Scope of the Reductive Aldol Reaction: Application to Aromatic Carbocycles and Heterocycles  
 
Timothy J. Donohoe,* David House and K. W. Ace  
 
Organic and Biomolecular Chemistry, 2003, 3749 - 3757. [link to journal]  
 
   
 
58
The Tethered Aminohydroxylation (TA) Reaction  
 
Timothy J. Donohoe,* Peter D. Johnson and Richard J. Pye  
 
Organic and Biomolecular Chemistry, 2003, 1, 2025-2028. [link to journal]  
 
   
 
57
Scope of the Directed Dihydroxylation: Application to Cyclic Homoallylic Alcohols and Trihaloacetamides  
 
Timothy J. Donohoe,* Lee Mitchell, Michael J. Waring, Madeleine Helliwell, Andrew Bell, and Nicholas J. Newcombe  
 
Organic and Biomolecular Chemistry, 2003, 1, 2173-2186. [link to journal]  
 
   
 
56
Flexibility in the Partial Reduction of 2,5-Disubstituted Pyrroles: Application to the Synthesis of DMDP  
 
Timothy J. Donohoe,* Catherine E. Headley, Rick P. C. Cousins and Andrew Cowley  
 
Organic Letters, 2003, 5, 999-1002. [link to journal]  
 
   
  55 A General Oxidative Cyclisation of 1,5-Dienes Using Catalytic Osmium Tetroxide  
 
Timothy J. Donohoe* and Sam Butterworth  
 
Angewandte Chemie Int Ed. Engl. 2003, 42, 948-951. [link to journal]  
 
   
 
54
Diastereoselective reductive aldol reactions of BOC-protected electron deficient pyrroles  
 
Timothy J. Donohoe* and David House  
 
Tetrahedron Letters, 2003, 44, 1095-1098. [link to journal]  
 
   
 
53
The Directed Dihydroxylation of Cyclic Allylic Alcohols and Trichloroacetamides Using OsO4/TMEDA  
 
Timothy J. Donohoe,* Kevin Blades, Peter R. Moore, Michael J. Waring, Jon J. G. Winter, Madeleine Helliwell, Nicholas J. Newcombe and Geoffrey Stemp  
 
Journal of Organic Chemistry, 2002, 67, 7946-7956. [link to journal]  
 
   
 
52

The Tethered Aminohydroxylation (TA) of Cyclic Allylic Carbamates

 
 
Timothy J. Donohoe,* Peter D. Johnson, Andrew Cowley and Martine Keenan  
 
Journal of the American Chemical Society, 2002, 124, 12934-12935. [link to journal]  
 
   
 
51
Synthesis of enantiopure dihydropyranones: aldol-based ring expansion of dihydrofurans  
 
Timothy J. Donohoe,* Ali Raoof, Graeme C. Freestone, Ian D. Linney, Andrew Cowley and Madeleine Helliwell  
 
Organic Letters, 2002, 4, 3059-3062. [link to journal]  
 
   
 
50
Partial reduction of 3-heteroatom substituted 2-furoic acids: the role of an ortho group on viability and stereoselectivity  
 
Timothy J. Donohoe,* Andrew A. Calabrese, Jean-Baptiste Guillermin, Christopher. S. Frampton and Daryl Walter  
 
J. Chem. Soc. Perkin Transactions 1, 2002, 1748-1756. [link to journal]  
 
   
 
49

Ammonia Free Reduction of Aromatic Compounds Using Lithium Di-tert-butylbiphenyl (LiDBB)

 
 
Timothy J. Donohoe* and David House  
 
Journal of Organic Chemistry, 2002, 67, 5015-5018. [link to journal]  
 
   
 
48
Preparation of (+)-Nemorensic Acid and Approaches to Nemorensine using the Partial Reduction of Electron Deficient Furans  
 
Timothy J. Donohoe,* Jean-Baptiste Guillermin and Daryl S. Walter  
 
J. Chem. Soc. Perkin Transactions 1, 2002, 1369-1375. [link to journal]  
 
   
 
47
Development of the Directed Dihydroxylation Reaction  
 
Timothy J. Donohoe  
 
Synlett, 2002, 1223. [link to journal]  
 
   
 
46
Transformations of 3,4-disubstituted pyridines under dissolving metal conditions-partial reduction followed by radical cyclisation  
 
Timothy J Donohoe,* Laura Mace, Madeleine Helliwell and Osamu Ichihara  
 
Synlett, 2002, 331-333. [link to journal]  
 
   
 
45
Homoallylic alcohols and trichloroacetamides as hydrogen bond donors for directed dihydroxylation  
 
Timothy J. Donohoe, L. Mitchell, M. J. Waring, M. Helliwell, A. Bell and N. J. Newcombe  
 
Tetrahedron Letters, 2001, 42, 8951-8954. [link to journal]  
 
   
 
44

The Regioselective Aminohydroxylation of Allylic Carbamates

 
 
Timothy J. Donohoe,* Peter D. Johnson, Madeleine Helliwell, and Martine Keenan,  
 
Chemical Communications, 2001, 2078. [link to journal]  
 
   
 
43
Silyl substituted furans in the stereoselective Birch reduction  
 
Timothy J Donohoe,* Andrew A. Calabrese, Jean-Baptiste Guillermin and Daryl S. Walter  
 
Tetrahedron Letters, 2001, 42, 5841. [link to journal]  
 
   
 
42
Use of Dissolving Metals in the Partial Reduction of Pyridines: Formation of 2-Alkyl-1,2-Dihydropyridines  
 
T. J. Donohoe,* Andrew J. McRiner, Madeleine Helliwell and Peter Sheldrake  
 
J. Chem. Soc. Perkin Transactions 1, 2001, 1435-1445. [link to journal]  
 
   
 
41
The partial reduction of annulated heterocycles as a general route to medium rings containing oxygen and nitrogen  
 
Timothy J. Donohoe,* Ali Raoof, Ian D. Linney and Madeleine Helliwell  
 
Organic Letters, 2001, 3, 861-864. [link to journal]  
 
   
 
40

Hydrogen bonding control in the oxidative cyclisation of 1,5-dienes

 
 
Timothy J. Donohoe,* Jonathan J. G. Winter, M. Helliwell and Geoffrey Stemp  
 
Tetrahedron Letters, 2001, 42, 971-974 [link to journal].  
 
   
 
39
Partial reduction of electron deficient pyridines  
 
T. J. Donohoe,* A. J. McRiner and P. Sheldrake  
 
Organic Letters, 2000, 2, 3861-3863. [link to journal]  
 
   
 
38
Stereoselective Reduction of Chiral 2-Furoic Acid Derivatives Using Group I Metals in Ammonia  
 
Timothy J. Donohoe,* Andrew A. Calabrese, Clare A. Stevenson and Tamara Ladduwahetty  
 
J. Chem. Soc. Perkin Transactions 1, 2000, 3724. [link to journal]  
 
   
 
37
Oxidation and Reduction in Organic Synthesis: OUP Chemistry Primer No. 6  
 
Timothy J. Donohoe  
 
Oxford University Press, 2000, ISBN 0198556640.  
 
   
 
36
A Syn Selective Dihydroxylation of Cyclic Allylic Trichloroacetamides Using Catalytic Osmium Tetroxide  
 
Kevin Blades, Timothy J. Donohoe,* Jonathan J. G. Winter and Geoffrey Stemp  
 
Tetrahedron Letters, 2000, 41, 4701-4704. [link to journal]  
 
   
 
35
The Synthesis of (+)-Nemorensic Acid  
 
Timothy J. Donohoe,* J. -B. Guillermin, C. Frampton and D. S. Walters  
 
J. Chem Soc., Chemical Communications, 2000, 465-466. [link to journal]  
 
   
 
34
The Partial Reduction of Hetereocycles: An Alternative to the Birch Reduction  
 
Timothy J. Donohoe,* Rakesh R. Harji and Rick P. C. Cousins  
 
Tetrahedron Letters, 2000, 41, 1331-1334. [link to journal]  
 
   
 
33
Stereoselective Reductive Alkylation of 2,5-disubstituted Pyrroles: A Role for Naphthalene in the Partial Reduction of Heterocycles  
 
Timothy J. Donohoe,* Rakesh R. Harji and Rick P. C. Cousins  
 
Tetrahedron Letters, 2000, 41, 1327-1330. [link to journal]  
 
   
 
32
Reductive Aldol Reactions on Aromatic Heterocycles  
 
Timothy J. Donohoe,* Karl W. Ace, Paul M. Guyo, Madeleine Helliwell and Jeffrey McKenna  
 
Tetrahedron Letters, 2000, 41, 989-993. [link to journal]  
 
   
 
31
Enhanced Stereoselectivity in the Catalytic Dihydroxylation of Acyclic Allylic Alcohols  
 
Timothy J. Donohoe,* Michael J. Waring, and Nicholas J. Newcombe  
 
Synlett, 2000, 149-151. [link to journal]  
 
   
 
30
1H- and 2H-Isoindoles  
 
Timothy J. Donohoe  
 
Science of Synthesis, Georg Thieme Verlag, 2000, Volume 10, 653-692. (Review).  
 
   
 
29
Birch Reduction of Aromatic Heterocycles  
 
Timothy J. Donohoe,* P. M. Guyo and A. Raoof  
 
Targets in Heterocyclic Systems, Italian Society of Chemistry, 1999, 3, 117-145 (Review).  
 
   
 
28
Syn Stereocontrol in the Directed Dihydroxylation of Ayclic Allylic Alcohols  
 
Timothy J. Donohoe,* Michael J. Waring and Nicholas J. Newcombe  
 
Tetrahedron Letters, 1999, 40, 6881-6884. [link to journal]  
 
   
 
27
The Synthesis of (-)-cis and (-)-trans-Crobarbatic Acid  
 
Timothy J. Donohoe,* C. A. Stevenson M. Helliwell, R. Irshad and T. Ladduwahetty  
 
Tetrahedron: Asymmetry, 1999, 10, 1315-1320. [link to journal]  
 
   
 
26
The Directed Dihydroxylation of Allylic Trichloroacetamides  
 
Timothy J. Donohoe,* Kevin Blades, Peter R. Moore, Jonathan J. G. Winter, Madeleine Helliwell and Geoffrey Stemp  
 
J. Org. Chem., 1999, 64, 2980-2981. [link to journal]  
 
   
 
25
Stereoselectivity in the double reductive alkylation of pyrroles: synthesis of cis-3,4-disubstituted pyrrolidines  
 
Timothy J. Donohoe,* Rakesh R. Harji and Rick P. C. Cousins  
 
J. Chem Soc., Chemical Communications, 1999, 141-142. [link to journal]  
 
   
 
24
The Stereoselective Birch Reduction of Pyrroles  
 
Timothy J. Donohoe*, P. M. Guyo and M. Helliwell  
 
Tetrahedron Letters, 1999, 40, 435-438. [link to journal]  
 
   
 
23
Synthesis of Amino-Sugars Using the Directed Dihydroxylation Reaction  
 
Timothy J. Donohoe,* Kevin Blades and Madeleine Helliwell  
 
J. Chem Soc., Chemical Communications, 1999, 1733-1734. [link to journal]  
 
   
 
22
The Synthesis of (+)-Pericosine B  
 
Timothy J. Donohoe*, K. Blades, M. Helliwell, M. J. Waring, and N. J. Newcombe  
 
Tetrahedron Lett., 1998, 39, 8755-8758. [link to journal]  
 
   
 
21
The Birch Reduction of 3-Substituted Pyrroles  
 
Timothy J. Donohoe*, P. M. Guyo, R. R. Harji and R. P. C. Cousins  
 
Tetrahedron Lett., 1998, 39, 3075-3078. [link to journal]  
 
   
 
20
Stereoselectivity in the Birch Reduction of 2-Furoic Acid Derivatives  
 
Timothy J. Donohoe*, M. Helliwell, C. A. Stevenson and T. Ladduwahetty  
 
Tetrahedron Lett., 1998, 39, 3071-3074. [link to journal]  
 
   
 
19
Applications of Stoichiometric Organotransition Metal Complexes in Organic Synthesis  
 
Timothy J. Donohoe,* Rakesh R. Harji, Peter R. Moore and Michael J. Waring  
 
J. Chem. Soc. Perkin Transactions 1, 1998, 819-859. (Review) [link to journal]  
 
   
 
18
The Reduction of Electron-Deficient Pyrroles Using Group I and II Metals in Ammonia  
 
Timothy J. Donohoe,* P. M. Guyo, R. L. Beddoes and M. Helliwell  
 
J. Chem. Soc. Perkin Transactions 1, 1998, 667-672. [link to journal]  
 
   
 
17
The Directed Dihydroxylation of Allylic Alcohols  
 
Timothy J. Donohoe,* Peter R. Moore, Michael J. Waring and Nicholas J. Newcombe  
 
Tetrahedron Lett., 1997, 38, 5027-5030. [link to journal]  
 
   
 
16
Applications of Stoichiometric Organotransition Metal Complexes in Organic Synthesis  
 
Timothy J. Donohoe,* Paul M. Guyo, Peter R. Moore and Clare A. Stevenson  
 
Cont. Org. Syn., 1997, 4, 22-39. (Review) [link to journal]  
 
   
 
15
Studies on the Role of Conformation and of Hydrogen-Bonding on the Dihydroxylation of Cyclic Allylic Alcohols: Application to the Synthesis of Conduritol D  
 
Timothy J. Donohoe,* Peter R. Moore and Roy L. Beddoes  
 
J. Chem. Soc. Perkin Transactions 1, 1997, 43-51. [link to journal]  
 
   
 
14
Birch Reduction of Electron-Deficient Pyrroles  
 
Timothy J. Donohoe* and Paul M. Guyo  
 
J. Org. Chem., 1996, 61, 7664-7665. [link to journal]  
 
   
 
13
On the Dihydroxylation of Cyclic Allylic Alcohols  
 
Timothy J. Donohoe,* Rina Garg and Peter R. Moore  
 
Tetrahedron Lett., 1996, 37, 3407-3410. [link to journal]  
 
   
 
12
Prospects for Stereocontrol in the Reduction of Aromatic Compounds  
 
Timothy J. Donohoe,* Rina Garg and Clare A. Stevenson  
 
Tetrahedron: Asymmetry, 1996, 7, 317-344. (Review) [link to journal]  
 
   
 
11
Stoichiometric Organotransition Metals in Organic Synthesis  
 
Timothy J. Donohoe  
 
Cont. Org. Syn., 1996, 3, 1-18. (Review) [link to journal]  
 
   
 
Publications
 
 
   
 
10
Taxane Diterpenes 3: Formation of the Eight-Membered B-Ring by Semi-Pinacol Rearrangement  
 
Philip Magnus, Louis Diorazio, Timothy J. Donohoe, Melvyn Giles, Philip Pye, James Tarrant and Stephen Thom  
 
Tetrahedron, 1996, 52, 14147-14176. [link to journal]  
 
   
 
9
Taxane Diterpenes 2: Synthesis of the 7-Deoxy ABC Taxane Skeleton, and Reactions of the A-Ring  
 
Philip Magnus, John Booth, Louis Diorazio, Timothy J. Donohoe, Vince Lynch, Nicholas Magnus, José Mendoza, Philip Pye and James G. Tarrant  
 
Tetrahedron, 1996, 52, 14103-14146. [link to journal]  
 
   
 
8
Taxane Diterpenes 1: Control of Relative and Absolute Stereochemistry in Intramolecular Pyrylium Ylide-Alkene Cyclizations for the Synthesis of Taxol Precursors  
 
William E. Bauta, John Booth, Mary E. Bos, Mark DeLuca, Louis Diorazio, Timothy J. Donohoe, Christopher Frost, Nicholas Magnus, Philip Magnus, José Mendoza, Philip Pye, James G. Tarrant, Stephen Thom and Feroze Ujjainwalla  
 
Tetrahedron, 1996, 52, 14081-14102. [link to journal]  
 
   
 
7
New Strategy for the Synthesis of the Taxane Diterpenes: Formation of the Eight-membered B-ring of Taxol by Semi-pinacol Rearrangement  
 
P. Magnus, L. Diorazio, T. J. Donohoe, M. Giles, P. Pye, J. Tarrant and S. Thom  
 
J. Chem. Soc., Chemical Communications, 1995, 1935-1936. [link to journal]  
 
   
 
6
New Strategy for the Synthesis of the Taxane Diterpenes: [5+2]- Pyrylium Ylide-Alkene Cyclisation, Ring Expansion Strategy  
 
W. Bauta, J. Booth, M. Bos, M. DeLuca, L. Diorazio, T. J. Donohoe, N. Magnus, P. Magnus, J. Mendoza, P. Pye, J. Tarrant, S. Thom and F. Ujjainwalla  
 
Tetrahedron Lett., 1995, 36, 5327-5330. [link to journal]  
 
   
 
5
Chromium Tricarbonyl Stabilised Benzylic Carbocations  
 
Stephen G. Davies and Timothy J. Donohoe  
 
Synlett, 1993, 323-332. [link to journal]  
 
   
 
4
Asymmetric Synthesis via Homochiral o-Anisaldehyde Chromium Tricarbonyl  
 
Stephen G. Davies and Timothy J. Donohoe  
 
H. Werner, A. G. Griesbeck, W. Adam, G. Bringmann, and W. Kiefer (Eds) Selective Reactions of Metal-Activated Molecules, Vieweg, Braunschweig 1992, 9-17. (Review)  
 
   
 
3

Stereoselective Manipulation of Acetals Derived from o-Substituted Benzaldehyde Chromium Tricarbonyl Complexes

 
 
Stephen G. Davies, Timothy J. Donohoe and J. M. J. Williams  
 
Pure and Appl. Chem., 1992, 64, 379-386. (Review) [link to journal]  
 
   
 
2

Asymmetric Synthesis of 2-Aryl-Tetrahydropyrans via Arene Chromium Tricarbonyl Methodology 2: 2-Aryl-3-Ethyl-4-Chloro-Tetrahydropyrans

 
 
Stephen. G. Davies, Timothy J. Donohoe and M. Anne Lister  
 
Tetrahedron: Asymmetry, 1991, 2, 1089-1092. [link to journal]  
 
   
 
1
Asymmetric Synthesis of 2-Aryl-Tetrahydropyrans via Arene Chromium Tricarbonyl Methodology 1: cis-2-Aryl-4-Chloro-Tetrahydropyrans  
 
 
Stephen G. Davies, Timothy J. Donohoe and M. Anne Lister  
 
 
Tetrahedron: Asymmetry, 1991, 2, 1085-1088. [link to journal]