Ashcroft, S.J.H. & Randle,P.J. (1970) Glucose
phosphorylation and glucose oxidation in mouse pancreatic
islets and the release of insulin. In "The Structure and
Metabolism of the pancreatic islets' Vol.2, Ed. by
Falkner,S., Hellman,B. & Taljedal,I-B. pp.225-232,
Pergamon Press, Oxford
Ashcroft, S.J.H., Hedeskov, C.J., Randle, P.J. (1970)
Glucose metabolism in mouse pancreatic islets. Biochem.J.
118, 143-154 PDF file
Ashcroft, S.J.H., Randle, P.J. (1970) Mechanisms in the
control of insulin release by glucose and other substrates.
In 'Early diabetes' Ed. by Camerini-Davalos,R. &
Role,H.S. pp.51-57, Academic Press, London
Ashcroft, S.J.H. & Randle,P.J. (1970) Enzymes of
glucose metabolism in normal mouse islets. Biochem.J. 119,
5-15 PDF file
Ashcroft, S.J.H. & Randle ,P.J. (1970) Bioenergetics of
islet function: islet glucose metabolism. Acta Diabet.Lat.
7, (Suppl.1), 159-175
Ashcroft, S.J.H., Bassett, J.M., Randle,P.J. (1971)
Isolation of human pancreatic islets capable of releasing
insulin and metabolizing glucose in vitro. Lancet 1,
888-889 PDF file
Ashcroft, S.J.H., Hedeskov, C.J., Randle, P.J. (1971) Islet
metabolism and insulin release: studies on normal mouse
pancreatic islets in vitro. Mem. Soc. Endocrin. 19, 503-518
Ashcroft, S.J.H., Bassett, J.M., Randle, P.J. (1972)
Insulin secretion mechanisms and glucose metabolism in
isolated islets. Diabetes 21, (Suppl.2), 538-545 PDF file
Ashcroft, S.J.H., Weerasinghe, L.C.C., Bassett, J.M.,
Randle, P.J. (1972) The pentose cycle and insulin release
in mouse pancreatic islets. Biochem.J. 126, 525-532
PDF file
Ashcroft, S.J.H., Randle, P.J., Taljedal, I-B. (1972)
Cyclic nucleotide phosphidiesterase activity in normal
mouse pancreatic islets. FEBS Letts. 20, 263-266 PDF file
Ashcroft, S.J.H., Capito, K., Hedeskov, C.J. (1973) Time
course studies of glucose-induced changes in glucose
6-phosphate and fructose 1:6-diphosphate content of mouse
and rat pancreatic islets. Diabetologia 9, 299-302 PDF file
Ashcroft, S.J.H., Weerasinghe, L.C.C., Randle, P.J. (1973)
Inter-relationships of islet metabolism, adenosine
triphosphate content and insulin release. Biochem.J. 132,
223-231 PDF file
Cooper, R.H., Ashcroft, S.J.H., Randle, P.J. (1973)
Concentration of adenosine 3',5'-cyclic monophosphate in
mouse pancreatic islets measured by a protein-binding
radioassay. Biochem.J. 132, 599-605 PDF file
Dormer, R.L., Kerbey, A.L., McPherson, M., Manley, S.,
Ashcroft, S.J.H., Schofield, J.G., Randle,P.J. (1974) The
effect of nickel on secretory systems. Studies on the
release of amylase, insulin and growth hormone. Biochem.J.
140, 135-142 PDf file
Dormer, R.L. & Ashcroft, S.J.H. (1974) Studies on the
role of calcium ions in the stimulation by adrenaline of
amylase release from rat parotid. Biochem.J. 144, 543-550
PDf file
Randle, P.J. & Ashcroft, S.J.H. (1975) The pancreas and
insulin release. In: "The physiological and biochemical
basis of diabetes'. Ed. by Vallance-Owen,J., pp 31-62,
Medical & Technical Publishing Co.Ltd., Lancaster
Ashcroft, S.J.H. & Crossley, J.R. (1975) The effect of
glucose, N-acetylglucosamine, glyceraldehyde and other
sugars on insulin release in vivo. Diabetologia 11, 279-284
PDF file
Findlay, J.R. & Ashcroft, S.J.H. (1975) Cells of the
islets of Langerhans. in: 'The cell in medical science' Ed.
by Lloyd,J. & Beck,F.C. pp 243-306, Academic Press,
London
Ashcroft, S.J.H., Crossley, J.R., Crossley, P.C. (1976) The
effect of N-acylglucosamines on the biosynthesis and
secretion of insulin in rat pancreatic islets. Biochem.J.
154, 701-707 PDF file
Ashcroft,S.J.H. (1976) The control of insulin release by
sugars. Ciba Fdn. Symposium 41 (new series) pp 117-139.
Sugden,M.C. & Ashcroft,S.J.H. (1977)
Phosphoenol-pyruvate in rat pancreatic islets: a possible
intracellular trigger of insulin release. Diabetologia 13,
481-486 PDF file
Ashcroft,S.J.H. & Nino,S. (1978) Effects of phloretin
and dextran-linked phloretin on pancreatic islet metabolism
and insulin release. Biochim.Biophys.Acta 528, 334-342 PDF file
Williams, I-H., & Ashcroft, S.J.H. (1978)
N-acetylglucosamine and the substrate-site hypothesis for
the control of insulin biosynthesis and secretion. FEBS
Letts. 87, 115-120 PDf file
Ashcroft, S.J.H. (1978) The use of glucose and analogues in
the elucidation of the mechanisms of insulin release and
biosynthesis. FEBS 11th Meeting, Vol.42, Symposium A1, pp
227-236
Sugden, M.C. & Ashcroft, S.J.H. (1978) Effects of
phosphoenol pyruvate, other glycolytic intermediates and
methylxanthines on calcium uptake by a mitochondrial
fraction from rat pancreatic islets. Diabetologia 15,
173-180 PDf file
Ashcroft, S.J.H., Bunce, J., Lowry, M., Hensen, S.E.,
Hedeskov, C.J. (1978) The effect of sugars on (pro)insulin
biosynthesis. Biochem.J. 174, 517-526 PDF file
Sugden, M.C., Ashcroft, S.J.H., Sugden, P.H. (1979) Protein
kinase activities in rat pancreatic islets of Langerhans.
Biochem.J. 180, 219-229 PDf file
Sugden, M.C., Christie, M.R., Ashcroft,S.J.H. (1979)
Presence and possible role of calcium-dependent regulator
(calmodulin) in rat islets of Langerhans. FEBS Letts. 105,
95-100 PDf file
Ashcroft, S.J.H. & Lowry, M. (1979) ß-Cell recognition
of steroisomers of D-glucose. Diabetologia 17, 165-168
PDf file
Ashcroft, S.J.H. & Christie, M.R. (1979) Effects of
glucose on the cytosolic ratio of reduced/oxidized
NADP+ in rat islets of Langerhans. Biochem. J.
184, 697-700 PDf file